164
N. N. Win and H. Morita
HO
OH
O
HO
OH
O
HO
OH
O
HO
OH
O
HO
O
OH
five possible structures of 132 (1,4-dihydroxy-1,4-dimethyl-7(1-methylethylidene)octahydroazulen-6(1H)-one-methane)
O
O
R
3
R
2
HO
R
1
R
4
133 (5,8-dihydroxy-3,5,8-trimethyl-4a,5,6,7,7a,8,9,9aoctahydroazuleno[6,5-b]furan-2(4H)-one)
R
1 = R
2 = α-H, R
3 = OH, R
4 = Me
134 (5,8-dihydroxy-3,5,8-trimethyl-4a,5,6,7,7a,8,9,9aoctahydroazuleno[6,5-b]furan-2(4H)-one)
R
1 = R
2 = β-H, R
3 = Me, R
4 = OH
O
O
HO
4a,5,6,7,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2(4H)-one)
OH
OH
OH
OH
OH
136 (7-(1-hydroxy-1-methylethyl)-1,4-dimethyl1,2,3,3a,4,5,8,8a-octahydroazulene-1,4-diol)
OH
Fig. 29 Structures of new guaiane-type sesquiterpenoids 132–136 isolated from C. comosa
rhizomes
OH
OH
137 (7-isopropenyl-1,4a-dimethyldecahydro-naphthalene-1,4-diol)
OH
152 (bisacumol)
O
O
H
153 (curcumenone)
Fig. 30 Structures of the eudesmane-type sesquiterpenoid 137, bisabolane-type sesquiterpenoid
152, and carabrane-type sesquiterpenoid 153 isolated from C. comosa rhizomes