Ir
N
Cl
Ar
CN
Ir
N
O
Ar
CN
H
O
Ir
N
H
Ar
CN
+ HCOO- Cl
-
CO 2
NAr
Ph
H
+ HCOO
-
NAr
Ph
H
Ir
N
H
Ar
CN
Ir
N
O
Ar
CN
H
O
TS 1
TS
2
NAr
Ph
TS 2
TS 1
Scheme 75 Catalytic cycle and transition states proposed by Xiao [240] for the TH of imine
catalysed by iridacycles using formic acid as the hydrogen donor
Scheme 76 Catalytic cycle proposed by Stirling [241] for the TH of imines catalysed by an iridium
CATHy catalyst. The rate-determining steps (RDS) for the formation of the R and S enantiomers are
indicated
Recent Advances in Iridium-Catalysed Transfer Hydrogenation Reactions
139
N
Cl
Ar
CN
Ir
N
O
Ar
CN
H
O
Ir
N
H
Ar
CN
+ HCOO- Cl
-
CO 2
NAr
Ph
H
+ HCOO
-
NAr
Ph
H
Ir
N
H
Ar
CN
Ir
N
O
Ar
CN
H
O
TS 1
TS
2
NAr
Ph
TS 2
TS 1
Scheme 75 Catalytic cycle and transition states proposed by Xiao [240] for the TH of imine
catalysed by iridacycles using formic acid as the hydrogen donor
Scheme 76 Catalytic cycle proposed by Stirling [241] for the TH of imines catalysed by an iridium
CATHy catalyst. The rate-determining steps (RDS) for the formation of the R and S enantiomers are
indicated
Recent Advances in Iridium-Catalysed Transfer Hydrogenation Reactions
139