rate profiles point out that the order of the transfer hydrogenation kinetics of the
iminium ion depends on the enantioface of the iminium implied in the hydride
transfer, being first order when the R enantiomer is formed and zero order for the
S enantiomer. On this background, one catalytic species could be operative for the
Scheme 74 Catalytic cycle proposed by Xiao [212] for the TH of N-heterocycles: 1,4-addition
(top), 1,2-addition (bottom)
138
M. Pilar Lamata et al.
iminium ion depends on the enantioface of the iminium implied in the hydride
transfer, being first order when the R enantiomer is formed and zero order for the
S enantiomer. On this background, one catalytic species could be operative for the
Scheme 74 Catalytic cycle proposed by Xiao [212] for the TH of N-heterocycles: 1,4-addition
(top), 1,2-addition (bottom)
138
M. Pilar Lamata et al.