Pang X, Wu Y, Wu Y, Lu B, Chen J, Wang J, Yi Z, Qu W, Liu M (2011) (À)-Gossypol suppresses
the growth of human prostate cancer xenografts via modulating VEGF signaling–mediated
angiogenesis. Mol Cancer Ther 10(5):795–805
Polley KR, Oswell NJ, Pegg RB, Paton CM, Cooper JA (2018) A 5-day high-fat diet rich in
cottonseed oil improves cholesterol profiles and triglycerides compared to olive oil in healthy
men. Nutr Res 60:43–53
Price WD, Lovell RA, McChesney DG (1993) Naturally occurring toxins in feedstuffs: center for
veterinary medicine perspective. J Anim Sci 71(9):2556–2562
Puckhaber LS, Dowd MK, Stipanovic RD, Howell CR (2002) Toxicity of (+)-and (À)-gossypol to
the plant pathogen, Rhizoctonia solani. J Agric Food Chem 50(24):7017–7021
Quintana PJ, de Peyster A, Klatzke S, Park HJ (2000) Gossypol-induced DNA breaks in rat
lymphocytes are secondary to cytotoxicity. Toxicol Lett 117(1–2):85–94
Radcliffe JD, Czajka-Narins DM (2006) Lipids and tocopherols in serum and liver of female rats
fed diets containing corn oil or cottonseed oil. Plant Foods Hum Nutr 61:35–38
Radcliffe JD, King CC, Czajka-Narins DM, Imrhan V (2001) Serum and liver lipids in rats fed diets
containing corn oil, cottonseed oil, or a mixture of corn and cottonseed oils. Plant Foods Hum
Nutr 56:51–60
Radcliffe JD, Czajka-Narins DM, Imrhan V (2004) Fatty acid composition of serum, adipose tissue
and liver in rats fed diets containing corn oil or cottonseed oil. Plant Foods Hum Nutr 69:73–77
Randel RD, Chase CC Jr, Wyse SJ (1992) Effects of gossypol and cottonseed products on
reproduction of mammals. J Anim Sci 70(5):1628–1638
Randel RD, Willard ST, Wyse SJ, French LN (1996) Effects of diets containing free gossypol on
follicular development, embryo recovery and corpus luteum function in Brangus heifers treated
with bFSH. Theriogenology 45(5):911–922
Rikihisa Y, Lin YC (1989) Effect of gossypol on the thyroid in young rats. J Comp Pathol 100
(4):411–417
Roger V, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, Camethon MR, Dai S,
Simone G, Ford ES (2011) Heart disease and stroke statistics: 2011 update. Circulation 123:
e18–e209
Rogers GM, Poore MH, Paschal JC (2002) Feeding cotton products to cattle. Vet Clin Food Anim
Pract 18(2):267–294
Ryan JR, Kratzer FA, Grats GR, Vohrra P (1986) Glandless cottonseed cake for laying and breeding
hens and broiler chicks. Poult Sci 65:549–955
Sacks FM, Katan M (2002) Randomized clinical trials on the effects of dietary fat and carbohydrate
on plasma lipoproteins and cardiovascular disease. Am J Med 113(9):13–24
Sadique J, Begum VH, Thenmozhi V, Elango V (1987) Hypoglycemic effect of cotton seed
aqueous extract in alloxan-induced diabetes mellitus in rats. Biochem Med Metab Biol 38
(1):104–110
Sahin A, Duru M, Kaya S, Camci O (2006) Effects of raw material in finisher diet on broiler
performance I choice feeding system. Arch Geflugelk 70(1):8–13
Schwingshackl L, Hoffmann G (2012) Monounsaturated fatty acids and risk of cardiovascular
disease: synopsis of the evidence available from systematic reviews and meta-analyses. Nutrition 4(12):1989–2007
Sekhar SC, Rao BVK (2011) Cottonseed oil as health oil. Pertanika J Trop Agric Sci 34(1):17–24
Singh V, Soni A, Kumar S, Singh R (2014) Characterization of liquid product obtained by pyrolysis
of cottonseed de-oiled cake. J Biobased Mater Bio 8:338–343
Siri-Tarino PW, Sun Q, Hu FB, Krauss RM (2010) Saturated fat, carbohydrate and cardiovascular
disease. Am J Clin Nutr 91(3):502–509
Soto-Blanco B (2008) Gossipol e fatores antinutricionais da soja. Toxicologia Aplicada à
Veterinária. Manole, São Paulo, pp 531–545
Tang F, Wong PYD (1984) Serum potassium and aldosterone levels in gossypol-treated rats. Int J
Androl 7(2):149–153
3 Cottonseed (Gossypium hirsutum)
9 1
the growth of human prostate cancer xenografts via modulating VEGF signaling–mediated
angiogenesis. Mol Cancer Ther 10(5):795–805
Polley KR, Oswell NJ, Pegg RB, Paton CM, Cooper JA (2018) A 5-day high-fat diet rich in
cottonseed oil improves cholesterol profiles and triglycerides compared to olive oil in healthy
men. Nutr Res 60:43–53
Price WD, Lovell RA, McChesney DG (1993) Naturally occurring toxins in feedstuffs: center for
veterinary medicine perspective. J Anim Sci 71(9):2556–2562
Puckhaber LS, Dowd MK, Stipanovic RD, Howell CR (2002) Toxicity of (+)-and (À)-gossypol to
the plant pathogen, Rhizoctonia solani. J Agric Food Chem 50(24):7017–7021
Quintana PJ, de Peyster A, Klatzke S, Park HJ (2000) Gossypol-induced DNA breaks in rat
lymphocytes are secondary to cytotoxicity. Toxicol Lett 117(1–2):85–94
Radcliffe JD, Czajka-Narins DM (2006) Lipids and tocopherols in serum and liver of female rats
fed diets containing corn oil or cottonseed oil. Plant Foods Hum Nutr 61:35–38
Radcliffe JD, King CC, Czajka-Narins DM, Imrhan V (2001) Serum and liver lipids in rats fed diets
containing corn oil, cottonseed oil, or a mixture of corn and cottonseed oils. Plant Foods Hum
Nutr 56:51–60
Radcliffe JD, Czajka-Narins DM, Imrhan V (2004) Fatty acid composition of serum, adipose tissue
and liver in rats fed diets containing corn oil or cottonseed oil. Plant Foods Hum Nutr 69:73–77
Randel RD, Chase CC Jr, Wyse SJ (1992) Effects of gossypol and cottonseed products on
reproduction of mammals. J Anim Sci 70(5):1628–1638
Randel RD, Willard ST, Wyse SJ, French LN (1996) Effects of diets containing free gossypol on
follicular development, embryo recovery and corpus luteum function in Brangus heifers treated
with bFSH. Theriogenology 45(5):911–922
Rikihisa Y, Lin YC (1989) Effect of gossypol on the thyroid in young rats. J Comp Pathol 100
(4):411–417
Roger V, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, Camethon MR, Dai S,
Simone G, Ford ES (2011) Heart disease and stroke statistics: 2011 update. Circulation 123:
e18–e209
Rogers GM, Poore MH, Paschal JC (2002) Feeding cotton products to cattle. Vet Clin Food Anim
Pract 18(2):267–294
Ryan JR, Kratzer FA, Grats GR, Vohrra P (1986) Glandless cottonseed cake for laying and breeding
hens and broiler chicks. Poult Sci 65:549–955
Sacks FM, Katan M (2002) Randomized clinical trials on the effects of dietary fat and carbohydrate
on plasma lipoproteins and cardiovascular disease. Am J Med 113(9):13–24
Sadique J, Begum VH, Thenmozhi V, Elango V (1987) Hypoglycemic effect of cotton seed
aqueous extract in alloxan-induced diabetes mellitus in rats. Biochem Med Metab Biol 38
(1):104–110
Sahin A, Duru M, Kaya S, Camci O (2006) Effects of raw material in finisher diet on broiler
performance I choice feeding system. Arch Geflugelk 70(1):8–13
Schwingshackl L, Hoffmann G (2012) Monounsaturated fatty acids and risk of cardiovascular
disease: synopsis of the evidence available from systematic reviews and meta-analyses. Nutrition 4(12):1989–2007
Sekhar SC, Rao BVK (2011) Cottonseed oil as health oil. Pertanika J Trop Agric Sci 34(1):17–24
Singh V, Soni A, Kumar S, Singh R (2014) Characterization of liquid product obtained by pyrolysis
of cottonseed de-oiled cake. J Biobased Mater Bio 8:338–343
Siri-Tarino PW, Sun Q, Hu FB, Krauss RM (2010) Saturated fat, carbohydrate and cardiovascular
disease. Am J Clin Nutr 91(3):502–509
Soto-Blanco B (2008) Gossipol e fatores antinutricionais da soja. Toxicologia Aplicada à
Veterinária. Manole, São Paulo, pp 531–545
Tang F, Wong PYD (1984) Serum potassium and aldosterone levels in gossypol-treated rats. Int J
Androl 7(2):149–153
3 Cottonseed (Gossypium hirsutum)
9 1