Gharby S, Harhar H, Guillaume D, Roudani A, Boulbaroud S, Ibrahimi M, Charrouf, Z (2015).
Chemical investigation of Nigella sativa L. seed oil produced in Morocco. Journal of the Saudi
Society of Agricultural Sciences, 14(2):172–177
Ghonime M, Eldomany R, Abdelaziz A, Soliman H (2011) Evaluation of immunomodulatory effect
of three herbal plants growing in Egypt. Immunopharmacol Immunotoxicol 33(1):141–145
Gilhotra N, Dhingra D (2011) Thymoquinone produced antianxiety-like effects in mice through
modulation of GABA and NO levels. Pharmacol Rep 63(3):660–669
Halamova K, Kokoska L, Flesar J, Sklenickova O, Svobodova B, Marsik P (2010) In vitro
antifungal effect of black cumin seed quinones against dairy spoilage yeasts at different acidity
levels. J Food Prot 73(12):2291–2295
Halawani E (2009) Antibacterial activity of thymoquinone and thymohydroquinone of Nigella
sativa L. and their interaction with some antibiotics. Adv Biol Res 3(5–6):148–152
Hanafy MS, Hatem ME (1991) Studies on the antimicrobial activity of Nigella sativa seed (black
cumin). J Ethnopharmacol 34(2–3):275–278
Hannan A, Saleem S, Chaudhary S, Barkaat M, Arshad MU (2008) Anti bacterial activity of Nigella
sativa against clinical isolates of methicillin resistant Staphylococcus aureus. J Ayub Med Coll
Abbottabad 20(3):72–74
Heshmati J, Namazi N (2015) Effects of black seed (Nigella sativa) on metabolic parameters in
diabetes mellitus: a systematic review. Complement Ther Med 23(2):275–282
Heshmati J, Namazi N, Memarzadeh MR, Taghizadeh M, Kolahdooz F (2015) Nigella sativa oil
affects glucose metabolism and lipid concentrations in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Food Res Int 70:87–93
Hossein BM, Nasim V, Sediqa A (2008). The protective effect of nigella sativa on lung injury of
sulfur mustard–exposed guinea pigs. Experimental Lung Research, 34(4):183-194
Hosseini MS, Mirkarimi SA, Amini M, Mohtashami R, Kianbakht S, Fallah HH (2013) Effects of
Nigella sativa L. seed oil in type II diabetic Patients: a randomized, double-blind, placebocontrolled clinical trial. J Med Plants 3(47):93–99
Hosseinzadeh H, Fazly Bazzaz BS, Haghi MM (2007) Antibacterial activity of total extracts and
essential oil of Nigella sativa L. seeds in mice. Pharmacology 2:429–435
Iriti M, Varoni EM (2017) Pulses, healthy, and sustainable food sources for feeding the planet. Int J
Mol Sci 18(3):640
Islam MT, Guha B, Hosen S, Riaz TA, Shahadat S (2017) Nigellalogy: a review on Nigella sativa.
MOJ Bioequiv Availab 3(6):00056
Javed S, Shahid AA, Haider MS, Umeera A, Ahmad R, Mushtaq S (2012) Nutritional, phytochemical potential and pharmacological evaluation of Nigella sativa (Kalonji) and Trachyspermum
ammi (Ajwain). J Med Plants Res 6(5):768–775
Kanter M, Coskun O, Budancamanak M (2005) Hepatoprotective effects of Nigella sativa L and
Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon
tetrachloride-treated rats. World J Gastroenterol: WJG 11(42):6684
Kanter M, Akpolat M, Aktas C (2009) Protective effects of the volatile oil of Nigella sativa seeds on
β-cell damage in streptozotocin-induced diabetic rats: a light and electron microscopic study. J
Mol Histol 40(5–6):379–385
Karna SKL (2013). Phytochemical screening and gas chromatography mass spectrometry and
analysis of seed extract of Nigella sativa Linn. Int J Chem Studies, 1(4):183–188
Khalife R, Hodroj MH, Fakhoury R, Rizk S (2016) Thymoquinone from Nigella sativa seeds
promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer
cells in vitro. Planta Med 82:312–321
Khan MAU, Ashfaq MK, Zuberi HS, Mahmood MS, Gilani AH (2003) The in vivo antifungal
activity of the aqueous extract from Nigella sativa seeds. Phytother Res 17(2):183–186
Khan A, Chen HC, Tania M, Zhang DZ (2011) Anticancer activities of Nigella sativa (black
cumin). Afr J Tradit Complement Altern Med 8(5S):226–232
Khare CP (2004) Encyclopedia of Indian medicinal plants. Springer-Verlag Berlin Heidelberg,
New York
13 Nigella (Nigella sativa) Seed
347
Chemical investigation of Nigella sativa L. seed oil produced in Morocco. Journal of the Saudi
Society of Agricultural Sciences, 14(2):172–177
Ghonime M, Eldomany R, Abdelaziz A, Soliman H (2011) Evaluation of immunomodulatory effect
of three herbal plants growing in Egypt. Immunopharmacol Immunotoxicol 33(1):141–145
Gilhotra N, Dhingra D (2011) Thymoquinone produced antianxiety-like effects in mice through
modulation of GABA and NO levels. Pharmacol Rep 63(3):660–669
Halamova K, Kokoska L, Flesar J, Sklenickova O, Svobodova B, Marsik P (2010) In vitro
antifungal effect of black cumin seed quinones against dairy spoilage yeasts at different acidity
levels. J Food Prot 73(12):2291–2295
Halawani E (2009) Antibacterial activity of thymoquinone and thymohydroquinone of Nigella
sativa L. and their interaction with some antibiotics. Adv Biol Res 3(5–6):148–152
Hanafy MS, Hatem ME (1991) Studies on the antimicrobial activity of Nigella sativa seed (black
cumin). J Ethnopharmacol 34(2–3):275–278
Hannan A, Saleem S, Chaudhary S, Barkaat M, Arshad MU (2008) Anti bacterial activity of Nigella
sativa against clinical isolates of methicillin resistant Staphylococcus aureus. J Ayub Med Coll
Abbottabad 20(3):72–74
Heshmati J, Namazi N (2015) Effects of black seed (Nigella sativa) on metabolic parameters in
diabetes mellitus: a systematic review. Complement Ther Med 23(2):275–282
Heshmati J, Namazi N, Memarzadeh MR, Taghizadeh M, Kolahdooz F (2015) Nigella sativa oil
affects glucose metabolism and lipid concentrations in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Food Res Int 70:87–93
Hossein BM, Nasim V, Sediqa A (2008). The protective effect of nigella sativa on lung injury of
sulfur mustard–exposed guinea pigs. Experimental Lung Research, 34(4):183-194
Hosseini MS, Mirkarimi SA, Amini M, Mohtashami R, Kianbakht S, Fallah HH (2013) Effects of
Nigella sativa L. seed oil in type II diabetic Patients: a randomized, double-blind, placebocontrolled clinical trial. J Med Plants 3(47):93–99
Hosseinzadeh H, Fazly Bazzaz BS, Haghi MM (2007) Antibacterial activity of total extracts and
essential oil of Nigella sativa L. seeds in mice. Pharmacology 2:429–435
Iriti M, Varoni EM (2017) Pulses, healthy, and sustainable food sources for feeding the planet. Int J
Mol Sci 18(3):640
Islam MT, Guha B, Hosen S, Riaz TA, Shahadat S (2017) Nigellalogy: a review on Nigella sativa.
MOJ Bioequiv Availab 3(6):00056
Javed S, Shahid AA, Haider MS, Umeera A, Ahmad R, Mushtaq S (2012) Nutritional, phytochemical potential and pharmacological evaluation of Nigella sativa (Kalonji) and Trachyspermum
ammi (Ajwain). J Med Plants Res 6(5):768–775
Kanter M, Coskun O, Budancamanak M (2005) Hepatoprotective effects of Nigella sativa L and
Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon
tetrachloride-treated rats. World J Gastroenterol: WJG 11(42):6684
Kanter M, Akpolat M, Aktas C (2009) Protective effects of the volatile oil of Nigella sativa seeds on
β-cell damage in streptozotocin-induced diabetic rats: a light and electron microscopic study. J
Mol Histol 40(5–6):379–385
Karna SKL (2013). Phytochemical screening and gas chromatography mass spectrometry and
analysis of seed extract of Nigella sativa Linn. Int J Chem Studies, 1(4):183–188
Khalife R, Hodroj MH, Fakhoury R, Rizk S (2016) Thymoquinone from Nigella sativa seeds
promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer
cells in vitro. Planta Med 82:312–321
Khan MAU, Ashfaq MK, Zuberi HS, Mahmood MS, Gilani AH (2003) The in vivo antifungal
activity of the aqueous extract from Nigella sativa seeds. Phytother Res 17(2):183–186
Khan A, Chen HC, Tania M, Zhang DZ (2011) Anticancer activities of Nigella sativa (black
cumin). Afr J Tradit Complement Altern Med 8(5S):226–232
Khare CP (2004) Encyclopedia of Indian medicinal plants. Springer-Verlag Berlin Heidelberg,
New York
13 Nigella (Nigella sativa) Seed
347