Asdadi A, Harhar H, Gharby S, Bouzoubaâ Z, Yadini AE, Moutaj R, Hadek ME, Chebli B, Hassani
LM (2014) Chemical composition and antifungal activity of Nigella sativa L. oil seed cultivated
in Morocco. Int J Pharm Sci Invent 3:9–15
Atta MB (2003) Some characteristics of nigella (Nigella sativa L.) seed cultivated in Egypt and its
lipid profile. Food Chem 83(1):63–68
Awad AB, Downie A, Fink CS, Kim U (2000) Dietary phytosterol inhibits the growth and
metastasis of MDA-MB-231 human breast cancer cells grown in SCID mice. Anticancer Res
20(2A):821–824
Babayan VK, Koottungal D, Halaby GA (1978) Proximate analysis, fatty acid and amino acid
composition of Nigella sativa L. seeds. J Food Sci 43(4):1314–1315
Badary OA, Taha RA, Gamal El-Din AM, Abdel-Wahab MH (2003) Thymoquinone is a potent
superoxide anion scavenger. Drug Chem Toxicol 26(2):87–98
Bamosa AO, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A (2010) Effect of Nigella sativa seeds
on the glycemic control of patients with type 2 diabetes mellitus. Indian J Physiol Pharmacol 54
(4):344–354
Bita A, Rosu AF, Calina D, Rosu L, Zlatian O, Dindere C, Simionescu A (2012) An alternative
treatment for Candida infections with Nigella sativa extracts. Eur J Hospital Pharma Science and
Pract 19(2):162
Boskabady MH, Javan H, Sajady M, Rakhshandeh H (2007). The possible prophylactic effect of
Nigella sativa seed extract in asthmatic patients. Fundamental & Clinical Pharmacology, 21
(5):559–566
Boudiaf K, Hurtado-Nedelec M, Belambri SA, Marie JC, Derradji Y, Benboubetra M, El-Benna J,
Dang PM (2016) Thymoquinone strongly inhibits fMLF-induced neutrophil functions and
exhibits anti-inflammatory properties in vivo. Biochem Pharmacol 104:62–73
Bourgou S, Ksouri R, Bellila A, Skandrani I, Falleh H, Marzouk B (2008) Phenolic composition
and biological activities of Tunisian Nigella sativa L. shoots and roots. C R Biol 331(1):48–55
Bourgou S, Pichette A, Marzouk B, Legault J (2012) Antioxidant, anti-inflammatory, anticancer
and antibacterial activities of extracts from Nigella sativa (black cumin) plant parts. J Food
Biochem 36(5):539–546
Canayakin D, Bayir Y, Kilic Baygutalp N, Sezen Karaoglan E, Atmaca HT, Kocak Ozgeris FB,
Keles MS, Halici Z (2016) Paracetamol-induced nephrotoxicity and oxidative stress in rats: the
protective role of Nigella sativa. Pharm Biol 54(10):2082–2091
Chehl N, Chipitsyna G, Gong Q, Yeo CJ, Arafat HA (2009) Anti-inflammatory effects of the
Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells. HPB 11(5):373–381
Cheikh-Rouhou S, Besbes S, Hentati B, Blecker C, Deroanne C, Attia H (2007) Nigella sativa L.:
chemical composition and physicochemical characteristics of lipid fraction. Food Chem 101
(2):673–681
Develi S, Evran B, Kalaz EB, Koçak-Toker N, Erata GÖ (2014) Protective effect of Nigella sativa
oil against binge ethanol-induced oxidative stress and liver injury in rats. Chin J Nat Med 12
(7):495–499
Edris AE (2010) Evaluation of the volatile oils from different local cultivars of Nigella sativa
L. grown in Egypt with emphasis on the effect of extraction method on thymoquinone. J Essent
Oil Bear Plants 13(2):154–164
El-Abhar HS, Abdallah DM, Saleh S (2003) Gastroprotective activity of Nigella sativa oil and its
constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in
rats. J Ethnopharmacol 84(2–3):251–258
El-Dakhakhny M, Mady NI, Halim MA (2000) Nigella sativa L. oil protects against induced
hepatotoxicity and improves serum lipid profile in rats. Arzneimittelforschung 50(09):832–836
El-Nagerabia SA, Al-Bahryb SN, Elshafieb AE, AlHilalib S (2012) Effect of Hibiscus sabdariffa
extract and Nigella sativa oil on the growth and aflatoxin B1 production of Aspergillus flavus
and Aspergillus parasiticus strains. Food Control 25:59–63
Ermumcu MŞ, Şanlıer N (2017) black cumin (Nigella sativa) and its active component of
thymoquinone: effects on health. J Food Health Sci 3(4):170–183
346
P. Sharma and T. Longvah
LM (2014) Chemical composition and antifungal activity of Nigella sativa L. oil seed cultivated
in Morocco. Int J Pharm Sci Invent 3:9–15
Atta MB (2003) Some characteristics of nigella (Nigella sativa L.) seed cultivated in Egypt and its
lipid profile. Food Chem 83(1):63–68
Awad AB, Downie A, Fink CS, Kim U (2000) Dietary phytosterol inhibits the growth and
metastasis of MDA-MB-231 human breast cancer cells grown in SCID mice. Anticancer Res
20(2A):821–824
Babayan VK, Koottungal D, Halaby GA (1978) Proximate analysis, fatty acid and amino acid
composition of Nigella sativa L. seeds. J Food Sci 43(4):1314–1315
Badary OA, Taha RA, Gamal El-Din AM, Abdel-Wahab MH (2003) Thymoquinone is a potent
superoxide anion scavenger. Drug Chem Toxicol 26(2):87–98
Bamosa AO, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A (2010) Effect of Nigella sativa seeds
on the glycemic control of patients with type 2 diabetes mellitus. Indian J Physiol Pharmacol 54
(4):344–354
Bita A, Rosu AF, Calina D, Rosu L, Zlatian O, Dindere C, Simionescu A (2012) An alternative
treatment for Candida infections with Nigella sativa extracts. Eur J Hospital Pharma Science and
Pract 19(2):162
Boskabady MH, Javan H, Sajady M, Rakhshandeh H (2007). The possible prophylactic effect of
Nigella sativa seed extract in asthmatic patients. Fundamental & Clinical Pharmacology, 21
(5):559–566
Boudiaf K, Hurtado-Nedelec M, Belambri SA, Marie JC, Derradji Y, Benboubetra M, El-Benna J,
Dang PM (2016) Thymoquinone strongly inhibits fMLF-induced neutrophil functions and
exhibits anti-inflammatory properties in vivo. Biochem Pharmacol 104:62–73
Bourgou S, Ksouri R, Bellila A, Skandrani I, Falleh H, Marzouk B (2008) Phenolic composition
and biological activities of Tunisian Nigella sativa L. shoots and roots. C R Biol 331(1):48–55
Bourgou S, Pichette A, Marzouk B, Legault J (2012) Antioxidant, anti-inflammatory, anticancer
and antibacterial activities of extracts from Nigella sativa (black cumin) plant parts. J Food
Biochem 36(5):539–546
Canayakin D, Bayir Y, Kilic Baygutalp N, Sezen Karaoglan E, Atmaca HT, Kocak Ozgeris FB,
Keles MS, Halici Z (2016) Paracetamol-induced nephrotoxicity and oxidative stress in rats: the
protective role of Nigella sativa. Pharm Biol 54(10):2082–2091
Chehl N, Chipitsyna G, Gong Q, Yeo CJ, Arafat HA (2009) Anti-inflammatory effects of the
Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells. HPB 11(5):373–381
Cheikh-Rouhou S, Besbes S, Hentati B, Blecker C, Deroanne C, Attia H (2007) Nigella sativa L.:
chemical composition and physicochemical characteristics of lipid fraction. Food Chem 101
(2):673–681
Develi S, Evran B, Kalaz EB, Koçak-Toker N, Erata GÖ (2014) Protective effect of Nigella sativa
oil against binge ethanol-induced oxidative stress and liver injury in rats. Chin J Nat Med 12
(7):495–499
Edris AE (2010) Evaluation of the volatile oils from different local cultivars of Nigella sativa
L. grown in Egypt with emphasis on the effect of extraction method on thymoquinone. J Essent
Oil Bear Plants 13(2):154–164
El-Abhar HS, Abdallah DM, Saleh S (2003) Gastroprotective activity of Nigella sativa oil and its
constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in
rats. J Ethnopharmacol 84(2–3):251–258
El-Dakhakhny M, Mady NI, Halim MA (2000) Nigella sativa L. oil protects against induced
hepatotoxicity and improves serum lipid profile in rats. Arzneimittelforschung 50(09):832–836
El-Nagerabia SA, Al-Bahryb SN, Elshafieb AE, AlHilalib S (2012) Effect of Hibiscus sabdariffa
extract and Nigella sativa oil on the growth and aflatoxin B1 production of Aspergillus flavus
and Aspergillus parasiticus strains. Food Control 25:59–63
Ermumcu MŞ, Şanlıer N (2017) black cumin (Nigella sativa) and its active component of
thymoquinone: effects on health. J Food Health Sci 3(4):170–183
346
P. Sharma and T. Longvah