Pan A, Yu D, Demark-Wahnefried W, Franco OH, Lin X (2009) Meta-analysis of the effects of
flaxseed interventions on blood lipids. Am J Clin Nutr 90(2):288–297
Park JB, Velasquez MT (2012) Potential effects of lignan-enriched flaxseed powder on bodyweight,
visceral fat, lipid profile, and blood pressure in rats. Fitoterapia 83:941–946
Patade A, Devareddy L, Lucas EA, Korlagunta BPD, Arjmandi BH (2008) Flaxseed reduces total
and LDL cholesterol concentrations in native American postmenopausal women. J Womens
Health (Larchmt) 17:355–366
Payne TJ (2000) Promoting better health with flaxseed in bread. Cereal Foods World 45
(3):102–104
Paynel F, Pavlov A, Ancelin G, Rihouey C, Picton L, Lebrun L, Morvan C (2013) Polysaccharide
hydrolases are released with mucilages after water hydration of flax seeds. Plant Physiol
Biochem 62:54–62
Pellizzon M, Billheimer JT, Bloedon LT, Szapary PO, Rader DJ (2007) Flaxseed reduces plasma
cholesterol levels in Hypercholesterolemic mouse models. J Am Coll Nutr 26(1):66–75
Penttinen P, Jaehrling J, Damdimopoulos AE, Inzunza J, Lemmen JG, van der Saag P, Pettersson K,
Gauglitz G, Makela S, Pongratz I (2007) Diet-derived polyphenol metabolite enterolactone is a
tissue-specific estrogen receptor activator. Endocrinology 148(10):4875–4886
Pisani P (2008) Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies. Arch
Physiol Biochem 114(1):63–70
Power KA, Thompson LU (2007) Can the combination of flaxseed and its lignans with soy and its
isoflavones reduce the growth stimulatory effect of soy and its isoflavones on established breast
cancer. Mol Nutr Food Res 51(7):845–856
Prasad K (1997) Hydroxyl radical–scavenging property of secoisolariciresinol diglycoside (SDG)
isolated from flax-seed. Mol Cell Biochem 168(1–2):117–123
Prasad K (1999) Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits
by secoisolariciresinol diglucoside isolated from flaxseed. Circulation 99:1355–1362
Prasad K (2000) Flaxseed: a source of hypocholesterolemic and anti atherogenic agents. Drug News
Perspect 13(2):99
Prasad K (2002) Suppression of phosphoenolpyruvatecarboxykinase gene expression by
secoisolariciresinoldiglucoside (SDG), a new antidiabetic agent. Int J Angiol 11(2):107–109
Prasad K (2004) Antihypertensive activity of secoisolariciresinol diglucoside (SDG) isolated from
flaxseed: role of guanylate cyclase. Int J Angiol 13:7–14
Prasad K, Mantha SV, Muir AD, Westcott ND (1998) Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alphalinolenic acid. Atherosclerosis 136:367–375
Prim CR, Baroncini LA, Precoma LB, Caron PH, Winter G, Poletti MO, Precoma DB (2012)
Effects of linseed consumption for a short period of time on lipid profile and atherosclerotic
lesions in rabbits fed a hypercholesterolaemic diet. Br J Nutr 107(5):660–664
Pruthi S, Thompson SL, Novotny PJ, Barton DL (2007) Pilot evaluation of flaxseed for the
management of hot flashes. J Soc Integr Oncol 5(3):106–112
Rajiv J, Indrani D, Prabhasankar P, Rao GV (2012) Rheology, fatty acid profile and storage
characteristics of cookies as influenced by flax seed (Linum usitatissimum). J Food Sci Technol
49(5):587–593
Ramcharitar N, Badrie M, Mattfeldt-Beman M, Matsuo H, Ridley C (2005) Consumer acceptability
of muffins with flaxseed (Linum usitatissimum). J Food Sci 70(7):504–507
Ray S, Paynel F, Morvan C, Lerouge P, Driouich A, Ray B (2013) Characterization of mucilage
polysaccharides, arabinogalactanproteins and cell-wall hemicellulosic polysaccharides isolated
from flax seed meal: a wealth of structural moieties. Carbohydr Polym 93:651–660
Ridges L, Sunderland R, Moerman K, Meyer B, Astheimer L, Howe P (2001) Cholesterol lowering
benefits of soy and linseed enriched foods. Asia Pac J Clin Nutr 10:204–211
Riediger ND, Othman R, Fitz E, Pierce GN, Suh M, Moghadasian MH (2009) Low n6:n3 fatty acid
ratio, with fish or flaxseed oil, in high fat diet improves plasma lipids and beneficially alters
tissue fatty acid composition in mice. Eur J Nutr 47:153–160
10 Flaxseed (Linum usitatissimum)
281
flaxseed interventions on blood lipids. Am J Clin Nutr 90(2):288–297
Park JB, Velasquez MT (2012) Potential effects of lignan-enriched flaxseed powder on bodyweight,
visceral fat, lipid profile, and blood pressure in rats. Fitoterapia 83:941–946
Patade A, Devareddy L, Lucas EA, Korlagunta BPD, Arjmandi BH (2008) Flaxseed reduces total
and LDL cholesterol concentrations in native American postmenopausal women. J Womens
Health (Larchmt) 17:355–366
Payne TJ (2000) Promoting better health with flaxseed in bread. Cereal Foods World 45
(3):102–104
Paynel F, Pavlov A, Ancelin G, Rihouey C, Picton L, Lebrun L, Morvan C (2013) Polysaccharide
hydrolases are released with mucilages after water hydration of flax seeds. Plant Physiol
Biochem 62:54–62
Pellizzon M, Billheimer JT, Bloedon LT, Szapary PO, Rader DJ (2007) Flaxseed reduces plasma
cholesterol levels in Hypercholesterolemic mouse models. J Am Coll Nutr 26(1):66–75
Penttinen P, Jaehrling J, Damdimopoulos AE, Inzunza J, Lemmen JG, van der Saag P, Pettersson K,
Gauglitz G, Makela S, Pongratz I (2007) Diet-derived polyphenol metabolite enterolactone is a
tissue-specific estrogen receptor activator. Endocrinology 148(10):4875–4886
Pisani P (2008) Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies. Arch
Physiol Biochem 114(1):63–70
Power KA, Thompson LU (2007) Can the combination of flaxseed and its lignans with soy and its
isoflavones reduce the growth stimulatory effect of soy and its isoflavones on established breast
cancer. Mol Nutr Food Res 51(7):845–856
Prasad K (1997) Hydroxyl radical–scavenging property of secoisolariciresinol diglycoside (SDG)
isolated from flax-seed. Mol Cell Biochem 168(1–2):117–123
Prasad K (1999) Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits
by secoisolariciresinol diglucoside isolated from flaxseed. Circulation 99:1355–1362
Prasad K (2000) Flaxseed: a source of hypocholesterolemic and anti atherogenic agents. Drug News
Perspect 13(2):99
Prasad K (2002) Suppression of phosphoenolpyruvatecarboxykinase gene expression by
secoisolariciresinoldiglucoside (SDG), a new antidiabetic agent. Int J Angiol 11(2):107–109
Prasad K (2004) Antihypertensive activity of secoisolariciresinol diglucoside (SDG) isolated from
flaxseed: role of guanylate cyclase. Int J Angiol 13:7–14
Prasad K, Mantha SV, Muir AD, Westcott ND (1998) Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alphalinolenic acid. Atherosclerosis 136:367–375
Prim CR, Baroncini LA, Precoma LB, Caron PH, Winter G, Poletti MO, Precoma DB (2012)
Effects of linseed consumption for a short period of time on lipid profile and atherosclerotic
lesions in rabbits fed a hypercholesterolaemic diet. Br J Nutr 107(5):660–664
Pruthi S, Thompson SL, Novotny PJ, Barton DL (2007) Pilot evaluation of flaxseed for the
management of hot flashes. J Soc Integr Oncol 5(3):106–112
Rajiv J, Indrani D, Prabhasankar P, Rao GV (2012) Rheology, fatty acid profile and storage
characteristics of cookies as influenced by flax seed (Linum usitatissimum). J Food Sci Technol
49(5):587–593
Ramcharitar N, Badrie M, Mattfeldt-Beman M, Matsuo H, Ridley C (2005) Consumer acceptability
of muffins with flaxseed (Linum usitatissimum). J Food Sci 70(7):504–507
Ray S, Paynel F, Morvan C, Lerouge P, Driouich A, Ray B (2013) Characterization of mucilage
polysaccharides, arabinogalactanproteins and cell-wall hemicellulosic polysaccharides isolated
from flax seed meal: a wealth of structural moieties. Carbohydr Polym 93:651–660
Ridges L, Sunderland R, Moerman K, Meyer B, Astheimer L, Howe P (2001) Cholesterol lowering
benefits of soy and linseed enriched foods. Asia Pac J Clin Nutr 10:204–211
Riediger ND, Othman R, Fitz E, Pierce GN, Suh M, Moghadasian MH (2009) Low n6:n3 fatty acid
ratio, with fish or flaxseed oil, in high fat diet improves plasma lipids and beneficially alters
tissue fatty acid composition in mice. Eur J Nutr 47:153–160
10 Flaxseed (Linum usitatissimum)
281