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Branched polyethylene glycol for protein precipitation.
Biotechnol
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24343
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Macromolecular crowding and protein stability. J Am Chem Soc 134(40):16614–16618.
https://doi.org/10.1021/ja305300m
52. Lewis GD, Metcalf TG (1988) Polyethylene
glycol precipitation for recovery of pathogenic
viruses, including hepatitis A virus and human
rotavirus, from oyster, water, and sediment
samples. Appl Environ Microbiol 54
(8):1983–1988
53. Ludwig A-K, de Miroschedji K, Doeppner TR
et al (2018) Precipitation with polyethylene
glycol followed by washing and pelleting by
ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small
and large scales. J Extracell Vesicles 7
(1):1528109.
https://doi.org/10.1080/
20013078.2018.1528109
54. Gagnon P, Toh P, Lee J (2014) High productivity purification of immunoglobulin G monoclonal antibodies on starch-coated magnetic
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https://doi.org/10.1016/j.chroma.2013.11.
039
55. Tao S-P, Zheng J, Sun Y (2015) Grafting zwitterionic polymer onto cryogel surface enhances
protein retention in steric exclusion chromatography on cryogel monolith. J Chromatogr
A 1389:104–111. https://doi.org/10.1016/j.
chroma.2015.02.051
56. Wang C, Bai S, Tao S-P et al (2014) Evaluation
of steric exclusion chromatography on cryogel
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Chromatogr A 1333:54–59. https://doi.org/
10.1016/j.chroma.2014.01.059
57. Marichal-Gallardo P, Pieler MM, Wolff MW
et al (2017) Steric exclusion chromatography
for purification of cell culture-derived influenza
A virus using regenerated cellulose membranes
and polyethylene glycol. J Chromatogr A
1483:110–119. https://doi.org/10.1016/j.
chroma.2016.12.076
58. Lothert K, Sprick G, Beyer F et al (2019)
Membrane-based steric exclusion chromatography for the purification of a recombinant
baculovirus and its application for cell therapy.
J Virol Methods 275:113756. https://doi.
org/10.1016/j.jviromet.2019.113756
59. (1998) WHO Expert Committee on biological
standardization. World Health Organ Tech
Rep Ser 878: i–vi, 1–101
60. Sheng-Fowler L, Lewis AM, Peden K (2009)
Issues associated with residual cell-substrate
DNA in viral vaccines. Biologicals 37
(3):190–195.
https://doi.org/10.1016/j.
biologicals.2009.02.015
61. Akpinar F, Yin J (2015) Characterization of
vesicular stomatitis virus populations by tunable resistive pulse sensing. J Virol Methods
218:71–76.
https://doi.org/10.1016/j.
jviromet.2015.02.006
62. Yang L, Yamamoto T (2016) Quantification of
virus particles using nanopore-based resistivepulse sensing techniques. Front Microbiol
7:1500.
https://doi.org/10.3389/fmicb.
2016.01500
63. Murphy RM (1997) Static and dynamic light
scattering of biological macromolecules: what
can we learn? Curr Opin Biotechnol 8
246
Keven Lothert et al.
Purification of new biologicals using
membrane-based processes. In: Basile A, Charcosset C (eds) Current trends and future developments on (bio-) membranes. Elsevier,
Amsterdam, pp 123–150
42. Transfiguracion J, Jorio H, Meghrous J et al
(2007) High yield purification of functional
baculovirus vectors by size exclusion chromatography. J Virol Methods 142(1–2):21–28.
https://doi.org/10.1016/j.jviromet.2007.
01.002
43. Kalbfuss B, Wolff M, Morenweiser R et al
(2007) Purification of cell culture-derived
human influenza A virus by size-exclusion and
anion-exchange chromatography. Biotechnol
Bioeng 96(5):932–944. https://doi.org/10.
1002/bit.21109
44. Lee J, Gan HT, Latiff SMA et al (2012) Principles and applications of steric exclusion chromatography. J Chromatogr A 1270:162–170.
https://doi.org/10.1016/j.chroma.2012.10.
062
45. Ingham KC (1978) Precipitation of proteins
with polyethylene glycol: characterization of
albumin. Arch Biochem Biophys 186
(1):106–1013
46. Atha DH, Ingham KC (1981) Mechanism of
precipitation of proteins by polyethylene glycols. J Biol Chem 256(23):12108–12117
47. Polson A (1977) A theory for the displacement
of proteins and viruses with polyethylene glycol. Prep Biochem 7:129–154
48. Arakawa T, Timasheff SN (1985) Mechanism
of poly(ethylene glycol) interaction with proteins. Biochemistry 24:6756–6762
49. Timasheff SN, Arakawa T (1988) Mechanism
of protein precipitation and stabilization by
co-solvents. J Cryst Growth 90:39–46
50. Sim S-L, He T, Tscheliessnig A et al (2012)
Branched polyethylene glycol for protein precipitation.
Biotechnol
Bioeng
109
(3):736–746. https://doi.org/10.1002/bit.
24343
51. Wang Y, Sarkar M, Smith AE et al (2012)
Macromolecular crowding and protein stability. J Am Chem Soc 134(40):16614–16618.
https://doi.org/10.1021/ja305300m
52. Lewis GD, Metcalf TG (1988) Polyethylene
glycol precipitation for recovery of pathogenic
viruses, including hepatitis A virus and human
rotavirus, from oyster, water, and sediment
samples. Appl Environ Microbiol 54
(8):1983–1988
53. Ludwig A-K, de Miroschedji K, Doeppner TR
et al (2018) Precipitation with polyethylene
glycol followed by washing and pelleting by
ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small
and large scales. J Extracell Vesicles 7
(1):1528109.
https://doi.org/10.1080/
20013078.2018.1528109
54. Gagnon P, Toh P, Lee J (2014) High productivity purification of immunoglobulin G monoclonal antibodies on starch-coated magnetic
nanoparticles by steric exclusion of polyethylene glycol. J Chromatogr A 1324:171–180.
https://doi.org/10.1016/j.chroma.2013.11.
039
55. Tao S-P, Zheng J, Sun Y (2015) Grafting zwitterionic polymer onto cryogel surface enhances
protein retention in steric exclusion chromatography on cryogel monolith. J Chromatogr
A 1389:104–111. https://doi.org/10.1016/j.
chroma.2015.02.051
56. Wang C, Bai S, Tao S-P et al (2014) Evaluation
of steric exclusion chromatography on cryogel
column for the separation of serum proteins. J
Chromatogr A 1333:54–59. https://doi.org/
10.1016/j.chroma.2014.01.059
57. Marichal-Gallardo P, Pieler MM, Wolff MW
et al (2017) Steric exclusion chromatography
for purification of cell culture-derived influenza
A virus using regenerated cellulose membranes
and polyethylene glycol. J Chromatogr A
1483:110–119. https://doi.org/10.1016/j.
chroma.2016.12.076
58. Lothert K, Sprick G, Beyer F et al (2019)
Membrane-based steric exclusion chromatography for the purification of a recombinant
baculovirus and its application for cell therapy.
J Virol Methods 275:113756. https://doi.
org/10.1016/j.jviromet.2019.113756
59. (1998) WHO Expert Committee on biological
standardization. World Health Organ Tech
Rep Ser 878: i–vi, 1–101
60. Sheng-Fowler L, Lewis AM, Peden K (2009)
Issues associated with residual cell-substrate
DNA in viral vaccines. Biologicals 37
(3):190–195.
https://doi.org/10.1016/j.
biologicals.2009.02.015
61. Akpinar F, Yin J (2015) Characterization of
vesicular stomatitis virus populations by tunable resistive pulse sensing. J Virol Methods
218:71–76.
https://doi.org/10.1016/j.
jviromet.2015.02.006
62. Yang L, Yamamoto T (2016) Quantification of
virus particles using nanopore-based resistivepulse sensing techniques. Front Microbiol
7:1500.
https://doi.org/10.3389/fmicb.
2016.01500
63. Murphy RM (1997) Static and dynamic light
scattering of biological macromolecules: what
can we learn? Curr Opin Biotechnol 8
246
Keven Lothert et al.