263
Lactobacillus delbrueckii ssp. lactis CRL 581 protects against trinitrobenzene sulfonic acidinduced colitis in mice. Journal of Dairy Science, 95, 1108–1118.
Expósito, I. L., & Recio, I. (2006). Antibacterial activity of peptides and folding variants from milk
proteins. International Dairy Journal, 16(11), 1294–1305.
Fadini, G. P., & Avogaro, A. (2011). Cardiovascular effects of DPP-4 inhibition: Beyond GLP-1.
Vascular Pharmacology, 55, 10–16.
Fernández-Tomé, S., Martínez-Maqueda, D., Girón, R., Goicoechea, C., Miralles, B., & Recio,
I. (2016). Novel peptides derived from αs1-casein with opioid activity and mucin stimulatory
effect on HT29-MTX cells. Journal of Functional Foods, 25, 466–476.
Ferreira, I. M. P. L. V. O., Pinho, O., Mota, M. V., Tavares, P., Pereira, A., Goncalves, M. P.,
… Teixeira, J. A. (2007). Preparation of ingredients containing an ACE-inhibitory peptide by
tryptic hydrolysis of whey protein concentrates. International Dairy Journal, 17(5), 481–487.
FitzGerald, R. J., Murray, B. A., & Walsh, D. J. (2004). Hypotensive peptides from milk proteins.
The Journal of Nutrition, 134(4), 980S–988S.
Frid, A. H., Nilsson, M., Holst, J. J., & Björck, I. M. (2005). Effect of whey on blood glucose
and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects. The
American Journal of Clinical Nutrition, 82(1), 69–75.
Furlong, S. J., Mader, J. S., & Hoskin, D. W. (2010). Bovine lactoferricin induces caspaseindependent apoptosis in human B-lymphoma cells and extends the survival of immunedeficient mice bearing B-lymphoma xenografts. Experimental and Molecular Pathology, 88,
371–375.
Garcia-Palmieri, M. R., Costas, R., Cruz-Vidal, M., Sorlie, P. D., Tillotson, J., & Havlik, R. J.
(1984). Milk consumption, calcium intake, and decreased hypertension in Puerto Rico. Puerto
Rico Heart Health Program study. Hypertension, 6(3), 322–328.
Gaudel, C., Nongonierma, A. B., Maher, S., Flynn, S., Krause, M., Murray, B. A., … Newsholme,
P. (2013). A whey protein hydrolysate promotes insulinotropic activity in a clonal pancreatic β-cell line and enhances glycemic function in ob/ob mice. Journal of Nutrition, 143(7),
1109–1114.
Gobbetti, M., Minervini, F., & Rizzello, C. G. (2004). Angiotensin i‐converting‐enzyme‐inhibitory and antimicrobial bioactive peptides. International Journal of Dairy Technology, 57(2‐3),
173–188.
Gobbetti, M., Stepaniak, L., De Angelis, M., Corsetti, A., & Di Cagno, R. (2002). Latent bioactive
peptides in milk proteins: Proteolytic activation and significance in dairy processing. Critical
Reviews in Food Science and Nutrition, 42(3), 223–239.
Goldman, A. S., Goldblum, R. M., & Hanson, L. Å. (1990). Anti-inflammatory systems in human
milk. In Antioxidant nutrients and immune functions (pp. 69–76). Boston, MA: Springer.
Gunnarsson, P. T., Winzell, M. S. r., Deacon, C. F., Larsen, M. O., Jelic, K., Carr, R. D., & Ahrén,
B. (2006). Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice. Endocrinology, 147(7), 3173–3180.
Hall, W. L., Millward, D. J., Long, S. J., & Morgan, L. M. (2003). Casein and whey exert different
effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite. British
Journal of Nutrition, 89(2), 239–248.
Hatzoglou, A., Bakogeorgou, E., Hatzoglou, C., Martin, P. M., & Castanas, E. (1996).
Antiproliferative and receptor binding properties of α-and β-casomorphins in the T47D human
breast cancer cell line. European Journal of Pharmacology, 310(2-3), 217–223.
Hedner, J., & Hedner, T. (1987). β-Casomorphins induce apnea and irregular breathing in adult rats
and newborn rabbits. Life Sciences, 41(20), 2303–2312.
Hernández-Ledesma, B., García-Nebot, M. J., Fernández-Tomé, S., Amigo, L., & Recio, I. (2014).
Dairy protein hydrolysates: Peptides for health benefits. International Dairy Journal, 38(2),
82–100.
Hoefle, A. S., Bangert, A. M., Stamfort, A., Gedrich, K., Rist, M. J., Lee, Y. M., … Daniel, H.
(2015). Metabolic responses of healthy or prediabetic adults to bovine whey protein and
sodium caseinate do not differ1–3. The Journal of Nutrition, 145(3), 467–475.
Nutraceutical Properties of Bioactive Peptides
Lactobacillus delbrueckii ssp. lactis CRL 581 protects against trinitrobenzene sulfonic acidinduced colitis in mice. Journal of Dairy Science, 95, 1108–1118.
Expósito, I. L., & Recio, I. (2006). Antibacterial activity of peptides and folding variants from milk
proteins. International Dairy Journal, 16(11), 1294–1305.
Fadini, G. P., & Avogaro, A. (2011). Cardiovascular effects of DPP-4 inhibition: Beyond GLP-1.
Vascular Pharmacology, 55, 10–16.
Fernández-Tomé, S., Martínez-Maqueda, D., Girón, R., Goicoechea, C., Miralles, B., & Recio,
I. (2016). Novel peptides derived from αs1-casein with opioid activity and mucin stimulatory
effect on HT29-MTX cells. Journal of Functional Foods, 25, 466–476.
Ferreira, I. M. P. L. V. O., Pinho, O., Mota, M. V., Tavares, P., Pereira, A., Goncalves, M. P.,
… Teixeira, J. A. (2007). Preparation of ingredients containing an ACE-inhibitory peptide by
tryptic hydrolysis of whey protein concentrates. International Dairy Journal, 17(5), 481–487.
FitzGerald, R. J., Murray, B. A., & Walsh, D. J. (2004). Hypotensive peptides from milk proteins.
The Journal of Nutrition, 134(4), 980S–988S.
Frid, A. H., Nilsson, M., Holst, J. J., & Björck, I. M. (2005). Effect of whey on blood glucose
and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects. The
American Journal of Clinical Nutrition, 82(1), 69–75.
Furlong, S. J., Mader, J. S., & Hoskin, D. W. (2010). Bovine lactoferricin induces caspaseindependent apoptosis in human B-lymphoma cells and extends the survival of immunedeficient mice bearing B-lymphoma xenografts. Experimental and Molecular Pathology, 88,
371–375.
Garcia-Palmieri, M. R., Costas, R., Cruz-Vidal, M., Sorlie, P. D., Tillotson, J., & Havlik, R. J.
(1984). Milk consumption, calcium intake, and decreased hypertension in Puerto Rico. Puerto
Rico Heart Health Program study. Hypertension, 6(3), 322–328.
Gaudel, C., Nongonierma, A. B., Maher, S., Flynn, S., Krause, M., Murray, B. A., … Newsholme,
P. (2013). A whey protein hydrolysate promotes insulinotropic activity in a clonal pancreatic β-cell line and enhances glycemic function in ob/ob mice. Journal of Nutrition, 143(7),
1109–1114.
Gobbetti, M., Minervini, F., & Rizzello, C. G. (2004). Angiotensin i‐converting‐enzyme‐inhibitory and antimicrobial bioactive peptides. International Journal of Dairy Technology, 57(2‐3),
173–188.
Gobbetti, M., Stepaniak, L., De Angelis, M., Corsetti, A., & Di Cagno, R. (2002). Latent bioactive
peptides in milk proteins: Proteolytic activation and significance in dairy processing. Critical
Reviews in Food Science and Nutrition, 42(3), 223–239.
Goldman, A. S., Goldblum, R. M., & Hanson, L. Å. (1990). Anti-inflammatory systems in human
milk. In Antioxidant nutrients and immune functions (pp. 69–76). Boston, MA: Springer.
Gunnarsson, P. T., Winzell, M. S. r., Deacon, C. F., Larsen, M. O., Jelic, K., Carr, R. D., & Ahrén,
B. (2006). Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice. Endocrinology, 147(7), 3173–3180.
Hall, W. L., Millward, D. J., Long, S. J., & Morgan, L. M. (2003). Casein and whey exert different
effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite. British
Journal of Nutrition, 89(2), 239–248.
Hatzoglou, A., Bakogeorgou, E., Hatzoglou, C., Martin, P. M., & Castanas, E. (1996).
Antiproliferative and receptor binding properties of α-and β-casomorphins in the T47D human
breast cancer cell line. European Journal of Pharmacology, 310(2-3), 217–223.
Hedner, J., & Hedner, T. (1987). β-Casomorphins induce apnea and irregular breathing in adult rats
and newborn rabbits. Life Sciences, 41(20), 2303–2312.
Hernández-Ledesma, B., García-Nebot, M. J., Fernández-Tomé, S., Amigo, L., & Recio, I. (2014).
Dairy protein hydrolysates: Peptides for health benefits. International Dairy Journal, 38(2),
82–100.
Hoefle, A. S., Bangert, A. M., Stamfort, A., Gedrich, K., Rist, M. J., Lee, Y. M., … Daniel, H.
(2015). Metabolic responses of healthy or prediabetic adults to bovine whey protein and
sodium caseinate do not differ1–3. The Journal of Nutrition, 145(3), 467–475.
Nutraceutical Properties of Bioactive Peptides