Contents
The Role of Total Synthesis in Structure Revision and Elucidation
of Decanolides (Nonanolides) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1
Bernd Schmidt
From Plant to Patient: Thapsigargin, a Tool for Understanding
Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy,
ATPases, Cell Death, and Drug Development . . . . . . . . . . . . . . . . . . . . . 59
Søren Brøgger Christensen, Henrik Toft Simonsen, Nikolai Engedal,
Poul Nissen, Jesper Vuust Møller, Samuel R. Denmeade,
and John T. Isaacs
Antileishmanial Activity of Lignans, Neolignans, and Other
Plant Phenols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115
Jiří Pospíšil, Daniela Konrádová, and Miroslav Strnad
Recent Advances in the Chemistry and Pharmacology
of Cryptolepine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177
Steven D. Shnyder and Colin W. Wright
vii
The Role of Total Synthesis in Structure Revision and Elucidation
of Decanolides (Nonanolides) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1
Bernd Schmidt
From Plant to Patient: Thapsigargin, a Tool for Understanding
Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy,
ATPases, Cell Death, and Drug Development . . . . . . . . . . . . . . . . . . . . . 59
Søren Brøgger Christensen, Henrik Toft Simonsen, Nikolai Engedal,
Poul Nissen, Jesper Vuust Møller, Samuel R. Denmeade,
and John T. Isaacs
Antileishmanial Activity of Lignans, Neolignans, and Other
Plant Phenols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115
Jiří Pospíšil, Daniela Konrádová, and Miroslav Strnad
Recent Advances in the Chemistry and Pharmacology
of Cryptolepine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177
Steven D. Shnyder and Colin W. Wright
vii
