cyanoacetic acid (up to 82% yield, 90% ee) [66], α-phenylthioacetonitriles [up to
99% yield, 95:5 dr (anti/syn), 99% ee (anti)] [67], α-aminoacetonitriles [up to 95%
yield, 97:3 dr (syn/anti), 99% ee (syn)] [68], dichloroacetonitrile (up to 99% yield,
94% ee) [69] and allenylnitriles (up to 89% yield, 99% ee) [70]. Whereas these
Scheme 36 Pincer complexes bearing two imidazolidine moieties as catalyst in enantioselective
reactions: (a) Michael addition (top); (b) Mannich reaction (bottom)
Scheme 37 Pincer complexes based on bis(imidazoline) ligands as catalyst in enantioselective
reactions
356
B. Guo et al.