the anhydrobiotic Tardigrade improve
osmotic tolerance of human cells. PLoS One
10:e0118272
11. Hatanaka R, Gusev O, Cornette R,
Shimura S, Kikuta S, Okada J, Okuda T, Kikawada T (2015) Diversity of the expression
profiles of late embryogenesis abundant
(LEA) protein encoding genes in the anhydrobiotic midge Polypedilum vanderplanki.
Planta 242:451–459
12. Wolkers WF, Alberda M, Koornneef M, LeonKloosterziel KM, Hoekstra FA (1998) Properties and the glassy matrix in maturation
defective mutant seed of Arabidopsis thaliana.
Plant J 16:133–143
13. Wolkers WF, Tetteroo FAA, Alberda M,
Hoekstra FA (1999) Changed properties of
the cytoplasmic matrix associated with desiccation tolerance of dried carrot somatic
embryos. An in situ Fourier transform infrared spectroscopic study. Plant Physiol
120:153–164
14. Wolkers WF, McCready S, Brandt WF, Lindsey GG, Hoekstra FA (2001) Isolation and
characterization of a D-7 LEA protein from
pollen that stabilizes glasses in vitro. Biochim
Biophys Acta 1544:196–206
15. Hoekstra FA, Golovina EA, Tetteroo FA,
Wolkers WF (2001) Induction of desiccation
tolerance in plant somatic embryos: how
exclusive is the protective role of sugars?
Cryobiology 43:140–150
16. Oldenhof H, Wolkers WF, Bowman JL,
Tablin F, Crowe JH (2006) Freezing and desiccation tolerance in the moss Physcomitrella
patens: an in situ Fourier transform infrared
spectroscopic study. Biochim Biophys Acta
1760:1226–1234
17. Mu ¨hlbacher F, Langer F, Mittermayer C
(1999) Preservation solutions for transplantation. Transpl Proc 31:2069–2070
18. Mazur P, Rall WF, Leibo SP (1984) Kinetics
of water loss and the likelihood of intracellular
freezing in mouse ova. Influence of the
method of calculating the temperature dependence of water permeability. Cell Biophys
6:197–213
19. Fahy GM, Wowk B (2015) Principles of cryopreservation by vitrification. In: Wolkers WF,
Oldenhof H (eds) Methods in cryopreservation and freeze-drying, methods in molecular
biology. Springer, New York, pp 21–82
20. Giwa S, Lewis JK, Alvarez L, Langer R, Roth
AE, Church GM, Markmann JF, Sachs DH,
Chandraker A, Wertheim JA, Rothblatt M,
Boyden ES, Eidbo E, Lee WPA, Pomahac B,
Brandacher G, Weinstock DM, Elliott G,
Nelson D, Acker JP, Uygun K, Schmalz B,
Weegman BP, Tocchio A, Fahy GM, Storey
KB, Rubinsky B, Bischof J, Elliott JAW,
Woodruff TK, Morris GJ, Demirci U, Brockbank KGM, Woods EJ, Ben RN, Baust JG,
Gao D, Fuller B, Rabin Y, Kravitz DC, Taylor
MJ, Toner M (2017) The promise of organ
and tissue preservation to transform medicine. Nat Biotechnol 35:530–542
21. Crowe JH, Carpenter JF, Crowe LM,
Anchordoguy TJ (1990) Are freezing and
dehydration similar stress vectors? A comparison of modes of interaction of stabilizing
solutes with biomolecules. Cryobiology
27:219–231
22. Pietramaggiori G, Kaipainen A, Ho D,
Orser C, Pebley W, Rudolph A, Orgill DP
(2007) Trehalose lyophilized platelets for
wound healing. Wound Repair Regen
15:213–220
23. Wakayama T, Yanagimachi R (1998) Development of normal mice from oocytes injected
with freeze-dried spermatozoa. Nat Biotechnol 7:639–641
24. Goecke T, Theodoridis K, Tudorache I,
Ciubotaru A, Cebotari S, Ramm R,
Ho ¨ffler K, Sarikouch S, Va ´squez Rivera A,
Haverich A, Wolkers WF, Hilfiker A (2018)
In vivo performance of freeze-dried decellularized pulmonary heart valve Allo- and xenografts orthotopically implanted into juvenile
sheep. Acta Biomater 68:41–52
25. Pegg DE (2015) Principles of cryopreservation. In: Wolkers WF, Oldenhof H (eds)
Methods in cryopreservation and freezedrying, methods in molecular biology.
Springer, New York, pp 3–19
26. Mazur P (1963) Kinetics of water loss from
cells at subzero temperatures and the likelihood of intracellular freezing. J Gen Physiol
47:347–369
27. Leibo SP, McGrath JJ, Cravalho EG (1978)
Microscopic observation of intracellular ice
formation in unfertilized mouse ova as a function
of
cooling
rate.
Cryobiology
15:257–271
28. Lovelock JE (1953) The mechanism of the
protective action of glycerol against haemolysis by freezing and thawing. Biochim Biophys
Acta 11:28–36
29. Lovelock JE (1953) The haemolysis of human
red blood cells by freezing and thawing. Biochim Biophys Acta 10:414–426
30. Steponkus PL, Uemura M, Joseph RA, Gilmour SJ, Thomashow MF (1998) Mode of
action of the COR15a gene on the freezing
Principles of Cryopreservation and Freeze-Drying
21
osmotic tolerance of human cells. PLoS One
10:e0118272
11. Hatanaka R, Gusev O, Cornette R,
Shimura S, Kikuta S, Okada J, Okuda T, Kikawada T (2015) Diversity of the expression
profiles of late embryogenesis abundant
(LEA) protein encoding genes in the anhydrobiotic midge Polypedilum vanderplanki.
Planta 242:451–459
12. Wolkers WF, Alberda M, Koornneef M, LeonKloosterziel KM, Hoekstra FA (1998) Properties and the glassy matrix in maturation
defective mutant seed of Arabidopsis thaliana.
Plant J 16:133–143
13. Wolkers WF, Tetteroo FAA, Alberda M,
Hoekstra FA (1999) Changed properties of
the cytoplasmic matrix associated with desiccation tolerance of dried carrot somatic
embryos. An in situ Fourier transform infrared spectroscopic study. Plant Physiol
120:153–164
14. Wolkers WF, McCready S, Brandt WF, Lindsey GG, Hoekstra FA (2001) Isolation and
characterization of a D-7 LEA protein from
pollen that stabilizes glasses in vitro. Biochim
Biophys Acta 1544:196–206
15. Hoekstra FA, Golovina EA, Tetteroo FA,
Wolkers WF (2001) Induction of desiccation
tolerance in plant somatic embryos: how
exclusive is the protective role of sugars?
Cryobiology 43:140–150
16. Oldenhof H, Wolkers WF, Bowman JL,
Tablin F, Crowe JH (2006) Freezing and desiccation tolerance in the moss Physcomitrella
patens: an in situ Fourier transform infrared
spectroscopic study. Biochim Biophys Acta
1760:1226–1234
17. Mu ¨hlbacher F, Langer F, Mittermayer C
(1999) Preservation solutions for transplantation. Transpl Proc 31:2069–2070
18. Mazur P, Rall WF, Leibo SP (1984) Kinetics
of water loss and the likelihood of intracellular
freezing in mouse ova. Influence of the
method of calculating the temperature dependence of water permeability. Cell Biophys
6:197–213
19. Fahy GM, Wowk B (2015) Principles of cryopreservation by vitrification. In: Wolkers WF,
Oldenhof H (eds) Methods in cryopreservation and freeze-drying, methods in molecular
biology. Springer, New York, pp 21–82
20. Giwa S, Lewis JK, Alvarez L, Langer R, Roth
AE, Church GM, Markmann JF, Sachs DH,
Chandraker A, Wertheim JA, Rothblatt M,
Boyden ES, Eidbo E, Lee WPA, Pomahac B,
Brandacher G, Weinstock DM, Elliott G,
Nelson D, Acker JP, Uygun K, Schmalz B,
Weegman BP, Tocchio A, Fahy GM, Storey
KB, Rubinsky B, Bischof J, Elliott JAW,
Woodruff TK, Morris GJ, Demirci U, Brockbank KGM, Woods EJ, Ben RN, Baust JG,
Gao D, Fuller B, Rabin Y, Kravitz DC, Taylor
MJ, Toner M (2017) The promise of organ
and tissue preservation to transform medicine. Nat Biotechnol 35:530–542
21. Crowe JH, Carpenter JF, Crowe LM,
Anchordoguy TJ (1990) Are freezing and
dehydration similar stress vectors? A comparison of modes of interaction of stabilizing
solutes with biomolecules. Cryobiology
27:219–231
22. Pietramaggiori G, Kaipainen A, Ho D,
Orser C, Pebley W, Rudolph A, Orgill DP
(2007) Trehalose lyophilized platelets for
wound healing. Wound Repair Regen
15:213–220
23. Wakayama T, Yanagimachi R (1998) Development of normal mice from oocytes injected
with freeze-dried spermatozoa. Nat Biotechnol 7:639–641
24. Goecke T, Theodoridis K, Tudorache I,
Ciubotaru A, Cebotari S, Ramm R,
Ho ¨ffler K, Sarikouch S, Va ´squez Rivera A,
Haverich A, Wolkers WF, Hilfiker A (2018)
In vivo performance of freeze-dried decellularized pulmonary heart valve Allo- and xenografts orthotopically implanted into juvenile
sheep. Acta Biomater 68:41–52
25. Pegg DE (2015) Principles of cryopreservation. In: Wolkers WF, Oldenhof H (eds)
Methods in cryopreservation and freezedrying, methods in molecular biology.
Springer, New York, pp 3–19
26. Mazur P (1963) Kinetics of water loss from
cells at subzero temperatures and the likelihood of intracellular freezing. J Gen Physiol
47:347–369
27. Leibo SP, McGrath JJ, Cravalho EG (1978)
Microscopic observation of intracellular ice
formation in unfertilized mouse ova as a function
of
cooling
rate.
Cryobiology
15:257–271
28. Lovelock JE (1953) The mechanism of the
protective action of glycerol against haemolysis by freezing and thawing. Biochim Biophys
Acta 11:28–36
29. Lovelock JE (1953) The haemolysis of human
red blood cells by freezing and thawing. Biochim Biophys Acta 10:414–426
30. Steponkus PL, Uemura M, Joseph RA, Gilmour SJ, Thomashow MF (1998) Mode of
action of the COR15a gene on the freezing
Principles of Cryopreservation and Freeze-Drying
21