33 Turn-on Mode Photoswitchable Fluorescent Diarylethenes …
577
which reveals unexplored structures and functions in biological systems and materials
[58–66].
Acknowledgements The present work was supported by JSPS KAKENHI Grant Numbers
JP15H01096, JP17H05272, Grant-in-Aid for Scientific Research on Innovative Areas “Photosynergetics.”
References
1. Fukaminato T (2011) Single-molecule fluorescence photoswitching: design and synthesis of
photoswitchable fluorescent molecules. J Photochem Photobiol, C 12:177–208
2. Zhang J, Zou Q, Tian H (2013) Photochromic materials: more than meets the eye. Adv Mater
25:378–399
3. Fukaminato T, Ishida S, Métivier R (2018) Photochromic fluorophores at the molecular and
nanoparticle levels: fundamentals and applications of diarylethenes. NPG Asia Mater 10:859–
881
4. Heilemann M, Dedecker P, Hofkens J, Sauer M (2009) Photoswitches: key molecules for
subdiffraction-resolution fluorescence imaging and molecular quantification. Laser Photon Rev
3:180–202
5. Fürstenberg A, Heilemann M (2013) Single-molecule localization microscopy–near molecular
spatial resolution in light microscopy with photoswitchable fluorophores. Phys Chem Chem
Phys 15:14919–14930
6. Yagi K, Soong CF, Irie M (2001) Synthesis of fluorescent diarylethenes having a 2,4,5triphenylimidazole chromophore. J Org Chem 66:5419–5423
7. Irie M, Fukaminato T, Sasaki T, Tamai N, Kawai T (2002) Organic chemistry: a digital
fluorescent molecular photoswitch. Nature 420:759–760
8. Fukaminato T, Sasaki T, Kawai T, Tamai N, Irie M (2004) Digital photoswitching of fluorescence based on the photochromism of diarylethene derivatives at a single-molecule level. J Am
Chem Soc 126:14843–14849
9. Fukaminato T, Umemoto T, Iwata Y, Yokojima S, Yoneyama M, Nakamura S, Irie M (2007)
Photochromism of diarylethene single molecules in polymer matrices. J Am Chem Soc
129:5932–5938
10. Fukaminato T, Doi T, Tamaoki N, Okuno K, Ishibashi Y, Miyasaka H, Irie M (2011)
Single-molecule fluorescence photoswitching of a diarylethene–perylenebisimide dyad: Nondestructive fluorescence readout. J Am Chem Soc 133:4984–4990
11. Golovkova TA, Kozlov DV, Neckers DC (2005) Synthesis and properties of novel fluorescent
switches. J Org Chem 70:5545–5549
12. Bossi M, Belov V, Polyakova S, Hell SW (2006) Reversible red fluorescent molecular switches.
Angew Chem Int Ed 45:7462–7465
13. Berberich M, Krause AM, Orlandi M, Scandola F, Würthner F (2008) Toward fluorescent
memories with nondestructive readout: photoswitching of fluorescence by intramolecular electron transfer in a diaryl ethene-perylene bisimide photochromic system. Angew Chem Int Ed
47:6616–6619
14. Berberich M, Natali M, Spenst P, Chiorboli C, Scandola F, Würthner F (2012) Nondestructive photoluminescence read-out by intramolecular electron transfer in a perylene
bisimide-diarylethene dyad. Chem Eur J 18:13651–13664
15. Hell SW, Jakobs S, Kastrup L (2003) Imaging and writing at the nanoscale with focused visible
light through saturable optical transitions. Appl Phys A 77:859–860
16. Grotjohann T, Testa I, Leutenegger M, Bock H, Urban NT, Lavoie-Cardinal F, Willig KI,
Eggelling C, Jakobs S, Hell SW (2011) Diffraction-unlimited all-optical imaging and writing
with a photochromic GFP. Nature 478:204–208
577
which reveals unexplored structures and functions in biological systems and materials
[58–66].
Acknowledgements The present work was supported by JSPS KAKENHI Grant Numbers
JP15H01096, JP17H05272, Grant-in-Aid for Scientific Research on Innovative Areas “Photosynergetics.”
References
1. Fukaminato T (2011) Single-molecule fluorescence photoswitching: design and synthesis of
photoswitchable fluorescent molecules. J Photochem Photobiol, C 12:177–208
2. Zhang J, Zou Q, Tian H (2013) Photochromic materials: more than meets the eye. Adv Mater
25:378–399
3. Fukaminato T, Ishida S, Métivier R (2018) Photochromic fluorophores at the molecular and
nanoparticle levels: fundamentals and applications of diarylethenes. NPG Asia Mater 10:859–
881
4. Heilemann M, Dedecker P, Hofkens J, Sauer M (2009) Photoswitches: key molecules for
subdiffraction-resolution fluorescence imaging and molecular quantification. Laser Photon Rev
3:180–202
5. Fürstenberg A, Heilemann M (2013) Single-molecule localization microscopy–near molecular
spatial resolution in light microscopy with photoswitchable fluorophores. Phys Chem Chem
Phys 15:14919–14930
6. Yagi K, Soong CF, Irie M (2001) Synthesis of fluorescent diarylethenes having a 2,4,5triphenylimidazole chromophore. J Org Chem 66:5419–5423
7. Irie M, Fukaminato T, Sasaki T, Tamai N, Kawai T (2002) Organic chemistry: a digital
fluorescent molecular photoswitch. Nature 420:759–760
8. Fukaminato T, Sasaki T, Kawai T, Tamai N, Irie M (2004) Digital photoswitching of fluorescence based on the photochromism of diarylethene derivatives at a single-molecule level. J Am
Chem Soc 126:14843–14849
9. Fukaminato T, Umemoto T, Iwata Y, Yokojima S, Yoneyama M, Nakamura S, Irie M (2007)
Photochromism of diarylethene single molecules in polymer matrices. J Am Chem Soc
129:5932–5938
10. Fukaminato T, Doi T, Tamaoki N, Okuno K, Ishibashi Y, Miyasaka H, Irie M (2011)
Single-molecule fluorescence photoswitching of a diarylethene–perylenebisimide dyad: Nondestructive fluorescence readout. J Am Chem Soc 133:4984–4990
11. Golovkova TA, Kozlov DV, Neckers DC (2005) Synthesis and properties of novel fluorescent
switches. J Org Chem 70:5545–5549
12. Bossi M, Belov V, Polyakova S, Hell SW (2006) Reversible red fluorescent molecular switches.
Angew Chem Int Ed 45:7462–7465
13. Berberich M, Krause AM, Orlandi M, Scandola F, Würthner F (2008) Toward fluorescent
memories with nondestructive readout: photoswitching of fluorescence by intramolecular electron transfer in a diaryl ethene-perylene bisimide photochromic system. Angew Chem Int Ed
47:6616–6619
14. Berberich M, Natali M, Spenst P, Chiorboli C, Scandola F, Würthner F (2012) Nondestructive photoluminescence read-out by intramolecular electron transfer in a perylene
bisimide-diarylethene dyad. Chem Eur J 18:13651–13664
15. Hell SW, Jakobs S, Kastrup L (2003) Imaging and writing at the nanoscale with focused visible
light through saturable optical transitions. Appl Phys A 77:859–860
16. Grotjohann T, Testa I, Leutenegger M, Bock H, Urban NT, Lavoie-Cardinal F, Willig KI,
Eggelling C, Jakobs S, Hell SW (2011) Diffraction-unlimited all-optical imaging and writing
with a photochromic GFP. Nature 478:204–208