1 3
Topics in Current Chemistry (2019) 377:23
2-naphthol(ate) partner 16 takes place to afford the homo-coupling product 17. The
chiral iron monophosphate Fe[(R)-L4] 3 acts as the active redox catalyst to control
stereoselectivity. As shown in Scheme 6, coupling takes place between two associated ligands via a radical-anion coupling mechanism. The formation of a persistent
Scheme 5 Enantioselective iron-catalyzed oxidative coupling of 1,1′-bi-2-naphthols
Scheme 6 Chiral iron phosphate-catalyzed counteranion-directed catalysis (CDC) reactions between
2-naphthols and β-ketoesters
Reprinted from the journal
159
Topics in Current Chemistry (2019) 377:23
2-naphthol(ate) partner 16 takes place to afford the homo-coupling product 17. The
chiral iron monophosphate Fe[(R)-L4] 3 acts as the active redox catalyst to control
stereoselectivity. As shown in Scheme 6, coupling takes place between two associated ligands via a radical-anion coupling mechanism. The formation of a persistent
Scheme 5 Enantioselective iron-catalyzed oxidative coupling of 1,1′-bi-2-naphthols
Scheme 6 Chiral iron phosphate-catalyzed counteranion-directed catalysis (CDC) reactions between
2-naphthols and β-ketoesters
Reprinted from the journal
159