1 3
Topics in Current Chemistry (2020) 378:16
o-chloranil by the Pd(II) complex. Further examination revealed that the palladium
catalyst instead binds efficiently to the oxygen of the intermediate C1-ammonium
enolate formed upon reaction with a ketene and the tertiary amine Lewis base catalyst. The role of palladium in this instance is clearly more complex than simply
increasing the electrophilicity of a substrate; O-Pd(II) ligation results in a more
Scheme 7 Asymmetric α-hydroxylation by Lectka
Reprinted from the journal
107
Topics in Current Chemistry (2020) 378:16
o-chloranil by the Pd(II) complex. Further examination revealed that the palladium
catalyst instead binds efficiently to the oxygen of the intermediate C1-ammonium
enolate formed upon reaction with a ketene and the tertiary amine Lewis base catalyst. The role of palladium in this instance is clearly more complex than simply
increasing the electrophilicity of a substrate; O-Pd(II) ligation results in a more
Scheme 7 Asymmetric α-hydroxylation by Lectka
Reprinted from the journal
107