30. Huang Y, Feng H, Liu W et al (2017) Cation-driven luminescent self-assembled dots of copper
nanoclusters with aggregation-induced emission for β-galactosidase activity monitoring.
J Mater Chem B 5:5120
31. Jia X, Li J, Wang E (2013) Cu nanoclusters with aggregation induced emission enhancement.
Small 9(22):3873
32. Jia X, Yang X, Li J et al (2014) Stable Cu nanoclusters: from an aggregation-induced emission
mechanism to biosensing and catalytic applications. Chem Commun 50(2):237
33. Wu Z, Liu J, Gao Y et al (2015) Assembly-induced enhancement of Cu nanoclusters luminescence with mechanochromic property. J Am Chem Soc 137(40):12906
34. Chen PC, Li YC, Ma JY et al (2016) Size-tunable copper nanocluster aggregates and their
application in hydrogen sulfide sensing on paper-based devices. Sci Rep 6:24882
35. Agostini A, Mondragón L, Bernardos A et al (2012) Targeted cargo delivery in senescent cells
using capped mesoporous silica nanoparticles. Angew Chem Int Ed 51(42):10556
36. Antropova YG, Bryantsev AL, Kalinina NI et al (2002) Proliferative activity and expression of
cyclin-dependent kinase inhibitor p21WAF1 and p53 protein in endothelial cells of human aorta
during replicative aging in vitro. Bull Exp Biol Med 134(1):81
37. Lee BY, Han JA, Im JS et al (2006) Senescence-associated β-galactosidase is lysosomal
β-galactosidase. Aging Cell 5(2):187
38. Leckaczernik B, Moerman EJ, Shmookler Reis RJ et al (1997) Cellular and molecular biomarkers indicate precocious in vitro senescence in fibroblasts from SAMP6 mice. Evidence
supporting a murine model of premature senescence and osteopenia. J Gerontol 52(6):B331
39. Gu Y, Wu Q, Zhu M et al (2011) Efficient pipeline configuration in distributed heterogeneous
computing environments. Aging Cell 10(2):338
40. Chigira S, Sugita K, Kita K et al (2003) Increased expression of the Huntingtin interacting
protein-1 gene in cells from Hutchinson Gilford Syndrome (Progeria) patients and aged donors.
J Gerontol 58(10):B873
41. Cabrera S, Haskouri JE, Guillem C et al (2000) Generalised syntheses of ordered mesoporous
oxides: the atrane route. Solid State Sci 2(4):405
42. Vallet-Regí M, Balas F, Arcos D (2007) Mesoporous materials for drug delivery. Angew Chem
Int Ed 46(40):7548
43. Auvray X, Petipas C, Anthore R et al (1995) X-ray diffraction study of the ordered lyotropic
phases formed by sugar-based surfactants. Langmuir 11(2):433
44. Tang C, Zhou J, Qian Z et al (2017) A universal fluorometric assay strategy for glycosidases
based on functional carbon quantum dots: β-galactosidase activity detection in vitro and in
living cells. J Mater Chem B 5(10):1971
45. Chen Y, Zhu C, Yang Z et al (2012) A new “turn-on” chemodosimeter for Hg
2+ : ICT
fluorophore formation via Hg
2+ -induced carbaldehyde recovery from 1,3-dithiane. Chem
Commun 48(42):5094
46. Zheng XT, Ananthanarayanan A, Luo KQ et al (2015) Glowing graphene quantum dots and
carbon dots: properties, syntheses, and biological applications. Small 11(14):1620
47. Lim SY, Shen W, Gao Z (2015) Carbon quantum dots and their applications. Chem Soc Rev 44
(1):362
48. Kim EJ, Kumar R, Sharma A et al (2017) In vivo imaging of β-galactosidase stimulated activity
in hepatocellular carcinoma using ligand-targeted fluorescent probe. Biomaterials 122:83
49. Prost M, Hasserodt J (2014) “Double gating” – a concept for enzyme-responsive imaging
probes aiming at high tissue specificity. Chem Commun 50(94):14896
50. Thorn-Seshold O, Vargas-Sanchez M, McKeon S et al (2012) A robust, high-sensitivity stealth
probe for peptidases. Chem Commun 48(50):6253
Fluorescent Probes for Diagnostics of β-Galactosidase: From Micro to Macro
201
nanoclusters with aggregation-induced emission for β-galactosidase activity monitoring.
J Mater Chem B 5:5120
31. Jia X, Li J, Wang E (2013) Cu nanoclusters with aggregation induced emission enhancement.
Small 9(22):3873
32. Jia X, Yang X, Li J et al (2014) Stable Cu nanoclusters: from an aggregation-induced emission
mechanism to biosensing and catalytic applications. Chem Commun 50(2):237
33. Wu Z, Liu J, Gao Y et al (2015) Assembly-induced enhancement of Cu nanoclusters luminescence with mechanochromic property. J Am Chem Soc 137(40):12906
34. Chen PC, Li YC, Ma JY et al (2016) Size-tunable copper nanocluster aggregates and their
application in hydrogen sulfide sensing on paper-based devices. Sci Rep 6:24882
35. Agostini A, Mondragón L, Bernardos A et al (2012) Targeted cargo delivery in senescent cells
using capped mesoporous silica nanoparticles. Angew Chem Int Ed 51(42):10556
36. Antropova YG, Bryantsev AL, Kalinina NI et al (2002) Proliferative activity and expression of
cyclin-dependent kinase inhibitor p21WAF1 and p53 protein in endothelial cells of human aorta
during replicative aging in vitro. Bull Exp Biol Med 134(1):81
37. Lee BY, Han JA, Im JS et al (2006) Senescence-associated β-galactosidase is lysosomal
β-galactosidase. Aging Cell 5(2):187
38. Leckaczernik B, Moerman EJ, Shmookler Reis RJ et al (1997) Cellular and molecular biomarkers indicate precocious in vitro senescence in fibroblasts from SAMP6 mice. Evidence
supporting a murine model of premature senescence and osteopenia. J Gerontol 52(6):B331
39. Gu Y, Wu Q, Zhu M et al (2011) Efficient pipeline configuration in distributed heterogeneous
computing environments. Aging Cell 10(2):338
40. Chigira S, Sugita K, Kita K et al (2003) Increased expression of the Huntingtin interacting
protein-1 gene in cells from Hutchinson Gilford Syndrome (Progeria) patients and aged donors.
J Gerontol 58(10):B873
41. Cabrera S, Haskouri JE, Guillem C et al (2000) Generalised syntheses of ordered mesoporous
oxides: the atrane route. Solid State Sci 2(4):405
42. Vallet-Regí M, Balas F, Arcos D (2007) Mesoporous materials for drug delivery. Angew Chem
Int Ed 46(40):7548
43. Auvray X, Petipas C, Anthore R et al (1995) X-ray diffraction study of the ordered lyotropic
phases formed by sugar-based surfactants. Langmuir 11(2):433
44. Tang C, Zhou J, Qian Z et al (2017) A universal fluorometric assay strategy for glycosidases
based on functional carbon quantum dots: β-galactosidase activity detection in vitro and in
living cells. J Mater Chem B 5(10):1971
45. Chen Y, Zhu C, Yang Z et al (2012) A new “turn-on” chemodosimeter for Hg
2+ : ICT
fluorophore formation via Hg
2+ -induced carbaldehyde recovery from 1,3-dithiane. Chem
Commun 48(42):5094
46. Zheng XT, Ananthanarayanan A, Luo KQ et al (2015) Glowing graphene quantum dots and
carbon dots: properties, syntheses, and biological applications. Small 11(14):1620
47. Lim SY, Shen W, Gao Z (2015) Carbon quantum dots and their applications. Chem Soc Rev 44
(1):362
48. Kim EJ, Kumar R, Sharma A et al (2017) In vivo imaging of β-galactosidase stimulated activity
in hepatocellular carcinoma using ligand-targeted fluorescent probe. Biomaterials 122:83
49. Prost M, Hasserodt J (2014) “Double gating” – a concept for enzyme-responsive imaging
probes aiming at high tissue specificity. Chem Commun 50(94):14896
50. Thorn-Seshold O, Vargas-Sanchez M, McKeon S et al (2012) A robust, high-sensitivity stealth
probe for peptidases. Chem Commun 48(50):6253
Fluorescent Probes for Diagnostics of β-Galactosidase: From Micro to Macro
201