controlled structures and intrinsic near-infrared emissions in the NIR-II window have
been developed to enable the acquisition of high-definition NIR-II images at wavelengths well in excess of 1,000 nm. These NIR-I and NIR-II fluorophores can be used to
develop diagnostics, biomedical imaging technologies, and drug discovery programs.
2.2 Targeted Ligand of Fluorescent Probes
In the field of medicinal chemistry, the target is the key element for the drug design
and development. FMI has the advantages of high sensitivity, convenience, reliability, and suitability for large-scale detection of drug targets. Using FMI, not only the
receptors, proteins, and genes that interact with drugs can be imaged, but the drug
targets can also be located and evaluated for their presence in an organism. The
spatial and temporal distribution of the target is evaluated quantitatively. Verification
Fig. 6 Representative NIR-II fluorophores
Fluorescence Molecular Imaging of Medicinal Chemistry in Cancer
7
been developed to enable the acquisition of high-definition NIR-II images at wavelengths well in excess of 1,000 nm. These NIR-I and NIR-II fluorophores can be used to
develop diagnostics, biomedical imaging technologies, and drug discovery programs.
2.2 Targeted Ligand of Fluorescent Probes
In the field of medicinal chemistry, the target is the key element for the drug design
and development. FMI has the advantages of high sensitivity, convenience, reliability, and suitability for large-scale detection of drug targets. Using FMI, not only the
receptors, proteins, and genes that interact with drugs can be imaged, but the drug
targets can also be located and evaluated for their presence in an organism. The
spatial and temporal distribution of the target is evaluated quantitatively. Verification
Fig. 6 Representative NIR-II fluorophores
Fluorescence Molecular Imaging of Medicinal Chemistry in Cancer
7