108
42. Nestler H et al (2012) Multiple-endpoint assay provides a detailed mechanistic view of responses
to herbicide exposure in Chlamydomonas reinhardtii. Aquat Toxicol 110-111:214–224
43. Nestler H et al (2012) Linking proteome responses with physiological and biochemical effects
in herbicide-exposed Chlamydomonas reinhardtii. J Proteome 75(17):5370–5385
44. Hidasi AO et al (2017) Clobetasol propionate causes immunosuppression in zebrafish (Danio
rerio) at environmentally relevant concentrations. Ecotoxicol Environ Saf 138:16–24
45. Di Paolo C et al (2015) Early life exposure to PCB126 results in delayed mortality and growth
impairment in the zebrafish larvae. Aquat Toxicol 169:168–178
46. Kirla KT et al (2018) Importance of toxicokinetics to assess the utility of zebrafish larvae as
model for psychoactive drug screening using meta-chlorophenylpiperazine (mCPP) as example. Front Pharmacol 9:414–414
47. Sturla SJ et al (2014) Systems toxicology: from basic research to risk assessment. Chem Res
Toxicol 27(3):314–329
48. Groh KJ, Nesatyy VJ, Suter MJ-F (2011) Proteomics for the analysis of environmental stress
responses in prokaryotes. In: de Bruijn FJ (ed) Handbook of molecular microbial ecology I:
Metagenomics and complementary approaches. Wiley-Blackwell, pp 603–625
49. Groh KJ et al (2013) Analysis of protein expression in zebrafish during gonad differentiation
by targeted proteomics. Gen Comp Endocrinol 193:210–220
50. Oliveira IB et al (2017) Toxicity of emerging antifouling biocides to non-target freshwater
organisms from three trophic levels. Aquat Toxicol 191:164–174
51. Tierbach A et al (2018) Glutathione S-transferase protein expression in different life stages of
zebrafish (Danio rerio). Toxicol Sci 162(2):702–712
52. Viant MR et al (2017) How close are we to complete annotation of metabolomes? Curr Opin
Chem Biol 36:64–69
53. van Straalen NM, Feder ME (2012) Ecological and evolutionary functional genomics—how
can it contribute to the risk assessment of chemicals? Environ Sci Technol 46(1):3–9
54. Groh KJ, Suter MJ-F (2015) Stressor-induced proteome alterations in zebrafish: a metaanalysis of response patterns. Aquat Toxicol 159:1–12
55. Tufi S et al (2016) Changes in neurotransmitter profiles during early zebrafish (Danio rerio)
development and after pesticide exposure. Environ Sci Technol 50(6):3222–3230
56. Taylor NS, Gavin A, Viant MR (2018) Metabolomics discovers early-response metabolic
biomarkers that can predict chronic reproductive fitness in individual Daphnia magna.
Meta 8(3):42
57. Viant MR, Sommer U (2013) Mass spectrometry based environmental metabolomics: a primer
and review. Metabolomics 9(1):144–158
58. Shu L, Suter MJ-F, Räsänen K (2015) Evolution of egg coats: linking molecular biology and
ecology. Mol Ecol 24(16):4052–4073
59. Sigg L et al (2014) Chemical aspects of nanoparticle ecotoxicology. CHIMIA Int J Chem
68(11):806–811
60. Groh KJ et al (2015) Critical influence of chloride ions on silver ion-mediated acute toxicity of
silver nanoparticles to zebrafish embryos. Nanotoxicology 9(1):81–91
61. Yue Y et al (2017) Interaction of silver nanoparticles with algae and fish cells: a side by side
comparison. J Nanobiotechnol 15(1):16–16
62. Aengenheister L et al (2019) Investigating the accumulation and translocation of titanium
dioxide nanoparticles with different surface modifications in static and dynamic human placental transfer models. Eur J Pharm Biopharm 142:488–497
63. Wigginton NS et al (2010) Binding of silver nanoparticles to bacterial proteins depends on
surface modifications and inhibits enzymatic activity. Environ Sci Technol 44(6):2163–2168
64. Yue Y et al (2016) Silver nanoparticle–protein interactions in intact rainbow trout gill cells.
Environ Sci Nano 3(5):1174–1185
K. J. Groh and M. J.-F. Suter
42. Nestler H et al (2012) Multiple-endpoint assay provides a detailed mechanistic view of responses
to herbicide exposure in Chlamydomonas reinhardtii. Aquat Toxicol 110-111:214–224
43. Nestler H et al (2012) Linking proteome responses with physiological and biochemical effects
in herbicide-exposed Chlamydomonas reinhardtii. J Proteome 75(17):5370–5385
44. Hidasi AO et al (2017) Clobetasol propionate causes immunosuppression in zebrafish (Danio
rerio) at environmentally relevant concentrations. Ecotoxicol Environ Saf 138:16–24
45. Di Paolo C et al (2015) Early life exposure to PCB126 results in delayed mortality and growth
impairment in the zebrafish larvae. Aquat Toxicol 169:168–178
46. Kirla KT et al (2018) Importance of toxicokinetics to assess the utility of zebrafish larvae as
model for psychoactive drug screening using meta-chlorophenylpiperazine (mCPP) as example. Front Pharmacol 9:414–414
47. Sturla SJ et al (2014) Systems toxicology: from basic research to risk assessment. Chem Res
Toxicol 27(3):314–329
48. Groh KJ, Nesatyy VJ, Suter MJ-F (2011) Proteomics for the analysis of environmental stress
responses in prokaryotes. In: de Bruijn FJ (ed) Handbook of molecular microbial ecology I:
Metagenomics and complementary approaches. Wiley-Blackwell, pp 603–625
49. Groh KJ et al (2013) Analysis of protein expression in zebrafish during gonad differentiation
by targeted proteomics. Gen Comp Endocrinol 193:210–220
50. Oliveira IB et al (2017) Toxicity of emerging antifouling biocides to non-target freshwater
organisms from three trophic levels. Aquat Toxicol 191:164–174
51. Tierbach A et al (2018) Glutathione S-transferase protein expression in different life stages of
zebrafish (Danio rerio). Toxicol Sci 162(2):702–712
52. Viant MR et al (2017) How close are we to complete annotation of metabolomes? Curr Opin
Chem Biol 36:64–69
53. van Straalen NM, Feder ME (2012) Ecological and evolutionary functional genomics—how
can it contribute to the risk assessment of chemicals? Environ Sci Technol 46(1):3–9
54. Groh KJ, Suter MJ-F (2015) Stressor-induced proteome alterations in zebrafish: a metaanalysis of response patterns. Aquat Toxicol 159:1–12
55. Tufi S et al (2016) Changes in neurotransmitter profiles during early zebrafish (Danio rerio)
development and after pesticide exposure. Environ Sci Technol 50(6):3222–3230
56. Taylor NS, Gavin A, Viant MR (2018) Metabolomics discovers early-response metabolic
biomarkers that can predict chronic reproductive fitness in individual Daphnia magna.
Meta 8(3):42
57. Viant MR, Sommer U (2013) Mass spectrometry based environmental metabolomics: a primer
and review. Metabolomics 9(1):144–158
58. Shu L, Suter MJ-F, Räsänen K (2015) Evolution of egg coats: linking molecular biology and
ecology. Mol Ecol 24(16):4052–4073
59. Sigg L et al (2014) Chemical aspects of nanoparticle ecotoxicology. CHIMIA Int J Chem
68(11):806–811
60. Groh KJ et al (2015) Critical influence of chloride ions on silver ion-mediated acute toxicity of
silver nanoparticles to zebrafish embryos. Nanotoxicology 9(1):81–91
61. Yue Y et al (2017) Interaction of silver nanoparticles with algae and fish cells: a side by side
comparison. J Nanobiotechnol 15(1):16–16
62. Aengenheister L et al (2019) Investigating the accumulation and translocation of titanium
dioxide nanoparticles with different surface modifications in static and dynamic human placental transfer models. Eur J Pharm Biopharm 142:488–497
63. Wigginton NS et al (2010) Binding of silver nanoparticles to bacterial proteins depends on
surface modifications and inhibits enzymatic activity. Environ Sci Technol 44(6):2163–2168
64. Yue Y et al (2016) Silver nanoparticle–protein interactions in intact rainbow trout gill cells.
Environ Sci Nano 3(5):1174–1185
K. J. Groh and M. J.-F. Suter