Atranorin
Atranorin has strong antioxidant and antitumor properties (Fig. 9). This lichen
compound has one of the largest free radical scavenging activities from lichen
substances tested and the most effective reducing power and superoxide radical
scavenging so far [50]. Another property of atranorin is anticancer activity against
cancer cell lines (A2780 and HT-29) which was demonstrated by Bačkorová et al.
[51]. This depside demonstrated strong pro-apoptic action and inhibition of cancer
cell proliferation. Atranorin is counted also as a potential anticancer agent in
hepatocytes from rat [52]. Antibacterial activities of this metabolite were also tested
[44, 45].
Thamnolic Acid
In the study of Cankılıç et al. [53], thamnolic acid showed potential antibacterial,
antituberculosis, and antifungal activities (Fig. 10). Strong effect of this compound
was determined also against bacteria and yeasts. This compound can be used as
potential antimicrobial agent in food industry and for the purpose of controlling
different diseases.
Fig. 8 Gyrophoric acid structure (Lasallia pustulata)
Fig. 9 Atranorin structure (Hypogymnia tubulosa)
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