IBU, NPX
x
x
Arabidopsis thaliana
–
plant, cell suspension
Cells grown in medium (drug
concentrations 2 mg L
À1
)
Liquid extraction of freezedried samples
SPE with Oasis HLB
UPLCQqQ-MS
2
LC-TOFMS
[28]
IPR
x
–
Typha latifolia
– plant
Pots
filled with perlite and
nutrition solution (20
μM IPR)
Ultrasonication extraction of
(under liquid nitrogen)
ground samples
SPE with Oasis HLB
LC-IT-MS
2
[85]
MET
x
–
Typha latifolia
– plant
Pots
filled with perlite and
nutrition solution (MET 6.5–
32.3 mg L
À1
)
Ultrasonic liquid extraction
SPE with Bond Elut LMS
LC-IT-MS
[84]
OBZ
x
x
Cyperus alternifolius
–
plant
Hydroponic in nutrient solution
(5–50
μM OBZ)
Liquid extraction of ground
samples
SPE with Oasis HLB
LC-IT-MS
[89]
OBZ
–
x
Horseradish
– hairy
root culture
Grown in Murashige and
Skoog medium (100
μM OBZ)
Ultrasonication extraction of
(under liquid nitrogen)
ground samples
SPE with Oasis HLB
LC-IT-MS
2
LC-TOFMS
[62]
PAR
–
x
Cucumber, common
bean, tomato, alfalfa,
wheat
– plant
Hydroponic in nutrient solution
(PAR 0.06–5 mg L
À1
)
Liquid extraction of freezedried samples
SPE with Oasis HLB
UPLCQqQ-MS
2
[41]
PAR
–
x
Horseradish
– hairy
root culture
Grown in Murashige and
Skoog media (1 mM PAR)
Samples ground in liquid
nitrogen and extracted with
liquid extraction
SPE with Strata-X
LC-IT-MS
2
[36]
SDZ, SMR, SMX,
SMZ, SPD
x
x
Canna indica, Iris
pseudacorus
– plant
Hydroponic in nutrition solution (drug concentrations 0.04–
2.4
μM)
Liquid extraction and cleanup
with graphitized carbon black
and octadecylsilane-silica
LC-QtrapMS
2
UPLCQTOF-MS
[83]
(continued)
Analytical Approaches for the Determination and Identification of Drug. . .
509