16. Li WC (2014) Occurrence, sources, and fate of pharmaceuticals in aquatic environment and
soil. Environ Pollut 187:193–201
17. Carter LJ, Harris E, Williams M, Ryan JJ, Kookana RS, Boxall AB (2014) Fate and uptake of
pharmaceuticals in soil-plant systems. J Agric Food Chem 62:816–825
18. Thiele-Bruhn S (2003) Pharmaceutical antibiotic compounds in soils – a review. J Plant Nutr
Soil Sci 166:145–167
19. Barra Caracciolo A, Topp E, Grenni P (2015) Pharmaceuticals in the environment: biodegradation and effects on natural microbial communities. A review. J Pharm Biomed Anal
106:25–36
20. Pullagurala VLR, Rawat S, Adisa IO, Hernandez-Viezcas JA, Peralta-Videa JR, GardeaTorresdey JL (2018) Plant uptake and translocation of contaminants of emerging concern in
soil. Sci Total Environ 636:1585–1596
21. Carter LJ, Agatz A, Kumar A, Williams M (2020) Translocation of pharmaceuticals from
wastewater into beehives. Environ Int 134:105248
22. Grossberger A, Hadar Y, Borch T, Chefetz B (2014) Biodegradability of pharmaceutical
compounds in agricultural soils irrigated with treated wastewater. Environ Pollut 185:168–177
23. Thelusmond JR, Kawka E, Strathmann TJ, Cupples AM (2018) Diclofenac, carbamazepine
and triclocarban biodegradation in agricultural soils and the microorganisms and metabolic
pathways affected. Sci Total Environ 640-641:1393–1410
24. Cycoń M, Borymski S, Żołnierczyk B, Piotrowska-Seget Z (2016) Variable effects of
non-steroidal anti-inflammatory drugs (NSAIDs) on selected biochemical processes mediated
by soil microorganisms. Front Microbiol 7:1969
25. Molaei A, Lakzian A, Datta R, Haghnia G, Astaraei A, Rasouli-Sadaghiani M, Ceccherini MT
(2017) Impact of chlortetracycline and sulfapyridine antibiotics on soil enzyme activities. Int
Agrophys 31:499–505
26. Sidhu H, O’Connor G, Ogram A, Kumar K (2019) Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: microbial toxicity and earthworm
responses. Sci Total Environ 650:18–26
27. Burns RG, DeForest JL, Marxsen J, Sinsabaugh RL, Stromberger ME, Wallenstein MD,
Weintraub MN, Zoppini A (2013) Soil enzymes in a changing environment: current knowledge and future directions. Soil Biol Biochem 58:216–234
28. Karlen DL, Ditzler CA, Andrews SS (2003) Soil quality: why and how. Geoderma
114:145–156
29. Karlen DL, Andrews SS, Doran JW (2001) Soil quality: current concepts and applications.
Adv Agron 74
30. Lal R (1997) Degradation and resilience of soils. Philos Trans R Soc Lond B Biol Sci
352:997–1010
31. Bender SF, Wagg C, van der Heijden MGA (2016) An underground revolution: biodiversity
and soil ecological engineering for agricultural sustainability. Trends Ecol Evol 31:440–452
32. Nielsen UN, Wall DH, Six J (2015) Soil biodiversity and the environment. Ann Rev Environ
Resour 40:63–90
33. Wagg C, Bender SF, Widmer F, van der Heijden MG (2014) Soil biodiversity and soil
community composition determine ecosystem multifunctionality. Proc Natl Acad Sci U S A
111:5266–5270
34. Shennan C, Krupnik TJ, Baird G, Cohen H, Forbush K, Lovell RJ, Olimpi E (2017) Organic
and conventional agriculture: a useful framing? Ann Rev Environ Res 42:317–346
35. Tsiafouli MA, Thébault E, Sgardelis SP, de Ruiter PC, van der Putten WH, Birkhofer K,
Hemerik L, de Vries FT, Bardgett RD, Brady MV, Bjornlund L, Jørgensen HB, Christensen S,
Hertefeldt TD, Hotes S, Gera Hol WH, Frouz J, Liiri M, Mortimer SR, Setälä H,
Tzanopoulos J, Uteseny K, Pižl V, Stary J, Wolters V, Hedlund K (2015) Intensive agriculture
reduces soil biodiversity across Europe. Glob Chang Biol 21:973–985
36. Briones MJI (2014) Soil fauna and soil functions: a jigsaw puzzle. Front Environ Sci 2. https://
doi.org/10.3389/fenvs.2014.00007
366
J. C. Sanchez-Hernandez
soil. Environ Pollut 187:193–201
17. Carter LJ, Harris E, Williams M, Ryan JJ, Kookana RS, Boxall AB (2014) Fate and uptake of
pharmaceuticals in soil-plant systems. J Agric Food Chem 62:816–825
18. Thiele-Bruhn S (2003) Pharmaceutical antibiotic compounds in soils – a review. J Plant Nutr
Soil Sci 166:145–167
19. Barra Caracciolo A, Topp E, Grenni P (2015) Pharmaceuticals in the environment: biodegradation and effects on natural microbial communities. A review. J Pharm Biomed Anal
106:25–36
20. Pullagurala VLR, Rawat S, Adisa IO, Hernandez-Viezcas JA, Peralta-Videa JR, GardeaTorresdey JL (2018) Plant uptake and translocation of contaminants of emerging concern in
soil. Sci Total Environ 636:1585–1596
21. Carter LJ, Agatz A, Kumar A, Williams M (2020) Translocation of pharmaceuticals from
wastewater into beehives. Environ Int 134:105248
22. Grossberger A, Hadar Y, Borch T, Chefetz B (2014) Biodegradability of pharmaceutical
compounds in agricultural soils irrigated with treated wastewater. Environ Pollut 185:168–177
23. Thelusmond JR, Kawka E, Strathmann TJ, Cupples AM (2018) Diclofenac, carbamazepine
and triclocarban biodegradation in agricultural soils and the microorganisms and metabolic
pathways affected. Sci Total Environ 640-641:1393–1410
24. Cycoń M, Borymski S, Żołnierczyk B, Piotrowska-Seget Z (2016) Variable effects of
non-steroidal anti-inflammatory drugs (NSAIDs) on selected biochemical processes mediated
by soil microorganisms. Front Microbiol 7:1969
25. Molaei A, Lakzian A, Datta R, Haghnia G, Astaraei A, Rasouli-Sadaghiani M, Ceccherini MT
(2017) Impact of chlortetracycline and sulfapyridine antibiotics on soil enzyme activities. Int
Agrophys 31:499–505
26. Sidhu H, O’Connor G, Ogram A, Kumar K (2019) Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: microbial toxicity and earthworm
responses. Sci Total Environ 650:18–26
27. Burns RG, DeForest JL, Marxsen J, Sinsabaugh RL, Stromberger ME, Wallenstein MD,
Weintraub MN, Zoppini A (2013) Soil enzymes in a changing environment: current knowledge and future directions. Soil Biol Biochem 58:216–234
28. Karlen DL, Ditzler CA, Andrews SS (2003) Soil quality: why and how. Geoderma
114:145–156
29. Karlen DL, Andrews SS, Doran JW (2001) Soil quality: current concepts and applications.
Adv Agron 74
30. Lal R (1997) Degradation and resilience of soils. Philos Trans R Soc Lond B Biol Sci
352:997–1010
31. Bender SF, Wagg C, van der Heijden MGA (2016) An underground revolution: biodiversity
and soil ecological engineering for agricultural sustainability. Trends Ecol Evol 31:440–452
32. Nielsen UN, Wall DH, Six J (2015) Soil biodiversity and the environment. Ann Rev Environ
Resour 40:63–90
33. Wagg C, Bender SF, Widmer F, van der Heijden MG (2014) Soil biodiversity and soil
community composition determine ecosystem multifunctionality. Proc Natl Acad Sci U S A
111:5266–5270
34. Shennan C, Krupnik TJ, Baird G, Cohen H, Forbush K, Lovell RJ, Olimpi E (2017) Organic
and conventional agriculture: a useful framing? Ann Rev Environ Res 42:317–346
35. Tsiafouli MA, Thébault E, Sgardelis SP, de Ruiter PC, van der Putten WH, Birkhofer K,
Hemerik L, de Vries FT, Bardgett RD, Brady MV, Bjornlund L, Jørgensen HB, Christensen S,
Hertefeldt TD, Hotes S, Gera Hol WH, Frouz J, Liiri M, Mortimer SR, Setälä H,
Tzanopoulos J, Uteseny K, Pižl V, Stary J, Wolters V, Hedlund K (2015) Intensive agriculture
reduces soil biodiversity across Europe. Glob Chang Biol 21:973–985
36. Briones MJI (2014) Soil fauna and soil functions: a jigsaw puzzle. Front Environ Sci 2. https://
doi.org/10.3389/fenvs.2014.00007
366
J. C. Sanchez-Hernandez