278. Sauvêtre A, May R, Harpaintner R, Poschenrieder C, Schröder P (2018) Metabolism of
carbamazepine in plant roots and endophytic rhizobacteria isolated from Phragmites australis.
J Hazard Mater 342:85–95. https://doi.org/10.1016/j.jhazmat.2017.08.006
279. Sauvêtre A, Schröder P (2015) Uptake of carbamazepine by rhizomes and endophytic bacteria
of Phragmites australis. Front Plant Sci 6:83. https://doi.org/10.3389/fpls.2015.00083
280. Wang Y, Lu J, Mao L, Li J, Yuan Z, Bond PL, Guo J (2019) Antiepileptic drug carbamazepine
promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and
across bacterial genera. ISME J 13:509–522. https://doi.org/10.1038/s41396-018-0275-x
281. Kapoor G, Saigal S, Elongavan A (2017) Action and resistance mechanisms of antibiotics: a
guide for clinicians. J Anaesthesiol Clin Pharmacol 33:300–305. https://doi.org/10.4103/
joacp.JOACP_349_15
282. Moulin G, Cavalié P, Pellanne I, Chevance A, Laval A, Millemann Y, Colin P, Chauvin C,
Antimicrobial Resistance ad hoc Group of the French Food Safety Agency (2008) A comparison of antimicrobial usage in human and veterinary medicine in France from 1999 to 2005. J
Antimicrob Chemother 62:617–625. https://doi.org/10.1093/jac/dkn213
283. Chang Q, Wang W, Regev-Yochay G, Lipsitch M, Hanage WP (2015) Antibiotics in agriculture and the risk to human health: how worried should we be? Evol Appl 8:240–247. https://
doi.org/10.1111/eva.12185
284. Manyi-Loh C, Mamphweli S, Meyer E, Okoh A (2018) Antibiotic use in agriculture and its
consequential resistance in environmental sources: potential public health implications. Molecules 23. https://doi.org/10.3390/molecules23040795
285. Stockwell VO, Duffy B (2012) Use of antibiotics in plant agriculture. OIE Rev Sci Tech
31:199–210. https://doi.org/10.20506/rst.31.1.2104
286. Lulijwa R, Rupia EJ, Alfaro AC (2019) Antibiotic use in aquaculture, policies and regulation,
health and environmental risks: a review of the top 15 major producers. Rev Aquac 1–24.
https://doi.org/10.1111/raq.12344
287. Vincent AT, Gauthier J, Derome N, Charette SJ (2019) The rise and fall of antibiotics in
aquaculture. In: Microbial communities in aquaculture ecosystems. Springer, Cham, pp 1–19.
https://doi.org/10.1007/978-3-030-16190-3_1
288. Dibner JJ, Richards JD (2005) Antibiotic growth promoters in agriculture: history and mode of
action. Poult Sci 84:634–643. https://doi.org/10.1093/ps/84.4.634
289. Hao H, Cheng G, Iqbal Z, Ai X, Hussain HI, Huang L, Dai M, Wang Y, Liu Z, Yuan Z (2014)
Benefits and risks of antimicrobial use in food-producing animals. Front Microbiol 5. https://
doi.org/10.3389/fmicb.2014.00288
290. Jay JM (1995) Antimicrobial food preservatives. In: Handbook of biocide and preservative
use. Springer, Dordrecht, pp 334–348. https://doi.org/10.1007/978-94-011-1354-0_12
291. Al-Jassim N, Hong P-Y (2017) Potential dissemination of ARB and ARGs into soil through
the use of treated wastewater for agricultural irrigation: is it a true cause for concern? In:
Hashmi M, Strezov V, V.A. (eds) Antibiotics and antibiotics resistance genes in soils. Soil
biology, vol 51. Springer, Cham, pp 105–139. https://doi.org/10.1007/978-3-319-66260-2_7
292. Amador PP, Fernandes RM, Prudêncio MC, Barreto MP, Duarte IM (2015) Antibiotic
resistance in wastewater: occurrence and fate of Enterobacteriaceae producers of class A and
class C β-lactamases. J Environ Sci Heal A Tox Hazard Subst Environ Eng 50:26–39. https://
doi.org/10.1080/10934529.2015.964602
293. Bouki C, Venieri D, Diamadopoulos E (2013) Detection and fate of antibiotic resistant bacteria
in wastewater treatment plants: a review. Ecotoxicol Environ Saf 91:1–9. https://doi.org/10.
1016/j.ecoenv.2013.01.016
294. Pan M, Chu LM (2017) Transfer of antibiotics from wastewater or animal manure to soil and
edible crops. Environ Pollut 231:829–836. https://doi.org/10.1016/j.envpol.2017.08.051
295. Pazda M, Kumirska J, Stepnowski P, Mulkiewicz E (2019) Antibiotic resistance genes
identified in wastewater treatment plant systems – a review. Sci Total Environ 697:134023.
https://doi.org/10.1016/j.scitotenv.2019.134023
Impact of PhACs on Soil Microorganisms
299
carbamazepine in plant roots and endophytic rhizobacteria isolated from Phragmites australis.
J Hazard Mater 342:85–95. https://doi.org/10.1016/j.jhazmat.2017.08.006
279. Sauvêtre A, Schröder P (2015) Uptake of carbamazepine by rhizomes and endophytic bacteria
of Phragmites australis. Front Plant Sci 6:83. https://doi.org/10.3389/fpls.2015.00083
280. Wang Y, Lu J, Mao L, Li J, Yuan Z, Bond PL, Guo J (2019) Antiepileptic drug carbamazepine
promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and
across bacterial genera. ISME J 13:509–522. https://doi.org/10.1038/s41396-018-0275-x
281. Kapoor G, Saigal S, Elongavan A (2017) Action and resistance mechanisms of antibiotics: a
guide for clinicians. J Anaesthesiol Clin Pharmacol 33:300–305. https://doi.org/10.4103/
joacp.JOACP_349_15
282. Moulin G, Cavalié P, Pellanne I, Chevance A, Laval A, Millemann Y, Colin P, Chauvin C,
Antimicrobial Resistance ad hoc Group of the French Food Safety Agency (2008) A comparison of antimicrobial usage in human and veterinary medicine in France from 1999 to 2005. J
Antimicrob Chemother 62:617–625. https://doi.org/10.1093/jac/dkn213
283. Chang Q, Wang W, Regev-Yochay G, Lipsitch M, Hanage WP (2015) Antibiotics in agriculture and the risk to human health: how worried should we be? Evol Appl 8:240–247. https://
doi.org/10.1111/eva.12185
284. Manyi-Loh C, Mamphweli S, Meyer E, Okoh A (2018) Antibiotic use in agriculture and its
consequential resistance in environmental sources: potential public health implications. Molecules 23. https://doi.org/10.3390/molecules23040795
285. Stockwell VO, Duffy B (2012) Use of antibiotics in plant agriculture. OIE Rev Sci Tech
31:199–210. https://doi.org/10.20506/rst.31.1.2104
286. Lulijwa R, Rupia EJ, Alfaro AC (2019) Antibiotic use in aquaculture, policies and regulation,
health and environmental risks: a review of the top 15 major producers. Rev Aquac 1–24.
https://doi.org/10.1111/raq.12344
287. Vincent AT, Gauthier J, Derome N, Charette SJ (2019) The rise and fall of antibiotics in
aquaculture. In: Microbial communities in aquaculture ecosystems. Springer, Cham, pp 1–19.
https://doi.org/10.1007/978-3-030-16190-3_1
288. Dibner JJ, Richards JD (2005) Antibiotic growth promoters in agriculture: history and mode of
action. Poult Sci 84:634–643. https://doi.org/10.1093/ps/84.4.634
289. Hao H, Cheng G, Iqbal Z, Ai X, Hussain HI, Huang L, Dai M, Wang Y, Liu Z, Yuan Z (2014)
Benefits and risks of antimicrobial use in food-producing animals. Front Microbiol 5. https://
doi.org/10.3389/fmicb.2014.00288
290. Jay JM (1995) Antimicrobial food preservatives. In: Handbook of biocide and preservative
use. Springer, Dordrecht, pp 334–348. https://doi.org/10.1007/978-94-011-1354-0_12
291. Al-Jassim N, Hong P-Y (2017) Potential dissemination of ARB and ARGs into soil through
the use of treated wastewater for agricultural irrigation: is it a true cause for concern? In:
Hashmi M, Strezov V, V.A. (eds) Antibiotics and antibiotics resistance genes in soils. Soil
biology, vol 51. Springer, Cham, pp 105–139. https://doi.org/10.1007/978-3-319-66260-2_7
292. Amador PP, Fernandes RM, Prudêncio MC, Barreto MP, Duarte IM (2015) Antibiotic
resistance in wastewater: occurrence and fate of Enterobacteriaceae producers of class A and
class C β-lactamases. J Environ Sci Heal A Tox Hazard Subst Environ Eng 50:26–39. https://
doi.org/10.1080/10934529.2015.964602
293. Bouki C, Venieri D, Diamadopoulos E (2013) Detection and fate of antibiotic resistant bacteria
in wastewater treatment plants: a review. Ecotoxicol Environ Saf 91:1–9. https://doi.org/10.
1016/j.ecoenv.2013.01.016
294. Pan M, Chu LM (2017) Transfer of antibiotics from wastewater or animal manure to soil and
edible crops. Environ Pollut 231:829–836. https://doi.org/10.1016/j.envpol.2017.08.051
295. Pazda M, Kumirska J, Stepnowski P, Mulkiewicz E (2019) Antibiotic resistance genes
identified in wastewater treatment plant systems – a review. Sci Total Environ 697:134023.
https://doi.org/10.1016/j.scitotenv.2019.134023
Impact of PhACs on Soil Microorganisms
299