83. Packer JL, Werner JJ, Latch DE, McNeill K, Arnold WA (2003) Photochemical fate of
pharmaceuticals in the environment: naproxen, diclofenac, clofibric acid, and ibuprofen.
Aquat Sci 65:342–351. https://doi.org/10.1007/s00027-003-0671-8
84. Vulava VM, Cory WC, Murphey VL, Ulmer CZ (2016) Sorption, photodegradation, and
chemical transformation of naproxen and ibuprofen in soils and water. Sci Total Environ
565:1063–1070. https://doi.org/10.1016/j.scitotenv.2016.05.132
85. Yamamoto H, Nakamura Y, Moriguchi S, Nakamura Y, Honda Y, Tamura I, Hirata Y,
Hayashi A, Sekizawa J (2009) Persistence and partitioning of eight selected pharmaceuticals
in the aquatic environment: laboratory photolysis, biodegradation, and sorption experiments.
Water Res 43:351–362. https://doi.org/10.1016/j.watres.2008.10.039
86. Thiele-Bruhn S, Peters D (2007) Photodegradation of pharmaceutical antibiotics on slurry and
soil surfaces. Landbauforsch Volkenrode 57:13–23
87. Aissaoui S, Ouled-Haddar H, Sifour M, Harrouche K, Sghaier H (2017) Metabolic and
co-metabolic transformation of diclofenac by Enterobacter hormaechei D15 isolated from
activated sludge. Curr Microbiol 74:381–388. https://doi.org/10.1007/s00284-016-1190-x
88. Amorim CL, Moreira IS, Maia AS, Tiritan ME, Castro PML (2014) Biodegradation of
ofloxacin, norfloxacin, and ciprofloxacin as single and mixed substrates by Labrys
portucalensis F11. Appl Microbiol Biotechnol 98:3181–3190. https://doi.org/10.1007/
s00253-013-5333-8
89. Kim YM, Murugesan K, Schmidt S, Bokare V, Jeon JR, Kim EJ, Chang YS (2011) Triclosan
susceptibility and co-metabolism – a comparison for three aerobic pollutant-degrading bacteria. Bioresour Technol 102:2206–2212. https://doi.org/10.1016/j.biortech.2010.10.009
90. Li Y, Wu B, Zhu G, Liu Y, Ng WJ, Appan A, Tan SK (2016) High-throughput
pyrosequencing analysis of bacteria relevant to cometabolic and metabolic degradation of
ibuprofen in horizontal subsurface flow constructed wetlands. Sci Total Environ 562:604–613.
https://doi.org/10.1016/j.scitotenv.2016.04.020
91. Marchlewicz A, Domaradzka D, Guzik U, Wojcieszyńska D (2016) Bacillus thuringiensis B1
(2015b) is a gram-positive bacteria able to degrade naproxen and ibuprofen. Water Air Soil
Pollut 227:197–197. https://doi.org/10.1007/s11270-016-2893-0
92. Marchlewicz A, Guzik U, Smułek W, Wojcieszyńska D (2017) Exploring the degradation of
ibuprofen by Bacillus thuringiensis B1(2015b): the new pathway and factors affecting degradation. Molecules 22:1676. https://doi.org/10.3390/molecules22101676
93. Moreira IS, Bessa VS, Murgolo S, Piccirillo C, Mascolo G, Castro PML (2018) Biodegradation of diclofenac by the bacterial strain Labrys portucalensis F11. Ecotoxicol Environ Saf
152:104–113. https://doi.org/10.1016/j.ecoenv.2018.01.040
94. Palyzová A, Zahradník J, Marešová H, Řezanka T (2019) Characterization of the catabolic
pathway of diclofenac in Raoultella sp. KDF8. Int Biodeter Biodegr 137:88–94. https://doi.
org/10.1016/j.ibiod.2018.11.013
95. Xu B, Xue G, Yang X (2018) Isolation and application of an ibuprofen-degrading bacterium to
a biological aerated filter for the treatment of micro-polluted water. Front Environ Sci Eng
12:1–8. https://doi.org/10.1007/s11783-018-1080-5
96. Żur J, Wojcieszyńska D, Hupert-Kocurek K, Marchlewicz A, Guzik U (2018) Paracetamol –
toxicity and microbial utilization. Pseudomonas moorei KB4 as a case study for exploring
degradation pathway. Chemosphere 206:192–202. https://doi.org/10.1016/j.chemosphere.
2018.04.179
97. Bessa VS, Moreira IS, Tiritan ME, Castro PML (2017) Enrichment of bacterial strains for the
biodegradation of diclofenac and carbamazepine from activated sludge. Int Biodeter Biodegr
120:135–142. https://doi.org/10.1016/j.ibiod.2017.02.008
98. De Gusseme B, Vanhaecke L, Verstraete W, Boon N (2011) Degradation of acetaminophen by
Delftia tsuruhatensis and Pseudomonas aeruginosa in a membrane bioreactor. Water Res
45:1829–1837. https://doi.org/10.1016/j.watres.2010.11.040
Impact of PhACs on Soil Microorganisms
287
pharmaceuticals in the environment: naproxen, diclofenac, clofibric acid, and ibuprofen.
Aquat Sci 65:342–351. https://doi.org/10.1007/s00027-003-0671-8
84. Vulava VM, Cory WC, Murphey VL, Ulmer CZ (2016) Sorption, photodegradation, and
chemical transformation of naproxen and ibuprofen in soils and water. Sci Total Environ
565:1063–1070. https://doi.org/10.1016/j.scitotenv.2016.05.132
85. Yamamoto H, Nakamura Y, Moriguchi S, Nakamura Y, Honda Y, Tamura I, Hirata Y,
Hayashi A, Sekizawa J (2009) Persistence and partitioning of eight selected pharmaceuticals
in the aquatic environment: laboratory photolysis, biodegradation, and sorption experiments.
Water Res 43:351–362. https://doi.org/10.1016/j.watres.2008.10.039
86. Thiele-Bruhn S, Peters D (2007) Photodegradation of pharmaceutical antibiotics on slurry and
soil surfaces. Landbauforsch Volkenrode 57:13–23
87. Aissaoui S, Ouled-Haddar H, Sifour M, Harrouche K, Sghaier H (2017) Metabolic and
co-metabolic transformation of diclofenac by Enterobacter hormaechei D15 isolated from
activated sludge. Curr Microbiol 74:381–388. https://doi.org/10.1007/s00284-016-1190-x
88. Amorim CL, Moreira IS, Maia AS, Tiritan ME, Castro PML (2014) Biodegradation of
ofloxacin, norfloxacin, and ciprofloxacin as single and mixed substrates by Labrys
portucalensis F11. Appl Microbiol Biotechnol 98:3181–3190. https://doi.org/10.1007/
s00253-013-5333-8
89. Kim YM, Murugesan K, Schmidt S, Bokare V, Jeon JR, Kim EJ, Chang YS (2011) Triclosan
susceptibility and co-metabolism – a comparison for three aerobic pollutant-degrading bacteria. Bioresour Technol 102:2206–2212. https://doi.org/10.1016/j.biortech.2010.10.009
90. Li Y, Wu B, Zhu G, Liu Y, Ng WJ, Appan A, Tan SK (2016) High-throughput
pyrosequencing analysis of bacteria relevant to cometabolic and metabolic degradation of
ibuprofen in horizontal subsurface flow constructed wetlands. Sci Total Environ 562:604–613.
https://doi.org/10.1016/j.scitotenv.2016.04.020
91. Marchlewicz A, Domaradzka D, Guzik U, Wojcieszyńska D (2016) Bacillus thuringiensis B1
(2015b) is a gram-positive bacteria able to degrade naproxen and ibuprofen. Water Air Soil
Pollut 227:197–197. https://doi.org/10.1007/s11270-016-2893-0
92. Marchlewicz A, Guzik U, Smułek W, Wojcieszyńska D (2017) Exploring the degradation of
ibuprofen by Bacillus thuringiensis B1(2015b): the new pathway and factors affecting degradation. Molecules 22:1676. https://doi.org/10.3390/molecules22101676
93. Moreira IS, Bessa VS, Murgolo S, Piccirillo C, Mascolo G, Castro PML (2018) Biodegradation of diclofenac by the bacterial strain Labrys portucalensis F11. Ecotoxicol Environ Saf
152:104–113. https://doi.org/10.1016/j.ecoenv.2018.01.040
94. Palyzová A, Zahradník J, Marešová H, Řezanka T (2019) Characterization of the catabolic
pathway of diclofenac in Raoultella sp. KDF8. Int Biodeter Biodegr 137:88–94. https://doi.
org/10.1016/j.ibiod.2018.11.013
95. Xu B, Xue G, Yang X (2018) Isolation and application of an ibuprofen-degrading bacterium to
a biological aerated filter for the treatment of micro-polluted water. Front Environ Sci Eng
12:1–8. https://doi.org/10.1007/s11783-018-1080-5
96. Żur J, Wojcieszyńska D, Hupert-Kocurek K, Marchlewicz A, Guzik U (2018) Paracetamol –
toxicity and microbial utilization. Pseudomonas moorei KB4 as a case study for exploring
degradation pathway. Chemosphere 206:192–202. https://doi.org/10.1016/j.chemosphere.
2018.04.179
97. Bessa VS, Moreira IS, Tiritan ME, Castro PML (2017) Enrichment of bacterial strains for the
biodegradation of diclofenac and carbamazepine from activated sludge. Int Biodeter Biodegr
120:135–142. https://doi.org/10.1016/j.ibiod.2017.02.008
98. De Gusseme B, Vanhaecke L, Verstraete W, Boon N (2011) Degradation of acetaminophen by
Delftia tsuruhatensis and Pseudomonas aeruginosa in a membrane bioreactor. Water Res
45:1829–1837. https://doi.org/10.1016/j.watres.2010.11.040
Impact of PhACs on Soil Microorganisms
287