24. Siemens J, Huschek G, Siebe C, Kaupenjohann M (2008) Concentrations and mobility of
human pharmaceuticals in the world’s largest wastewater irrigation system, Mexico CityMezquital Valley. Water Res 42:2124–2134
25. Biel-Maeso M, Corada-Fernández C, Lara-Martín PA (2018) Monitoring the occurrence of
pharmaceuticals in soils irrigated with reclaimed wastewater. Environ Pollut 235:312–321
26. Li J, Dodgen L, Ye Q, Gan J (2014) Degradation and transformation products of acetaminophen
in soil. Water Res 49:44–52
27. Corada-Fernández C, Jiménez-Martínez J, Candela L, González-Mazo E, Lara-Martín PA
(2015) Occurrence and spatial distribution of emerging contaminants in the unsaturated zone.
Case study: Guadalete River basin (Cadiz, Spain). Chemosphere 119:s131–s137
28. Dalkmann P, Broszat M, Siebe C, Willaschek E, Sakinc T, Huebner J, Amelung W,
Grohmann E, Siemens J (2012) Accumulation of pharmaceuticals, enterococcus, and resistance
genes in soils irrigated with wastewater for zero to 100 years in Central Mexico. PLoS One 7(9):
e45397
29. Christou A, Karaolia P, Hapeshi E, Michael C, Fatta-Kassinos D (2017) Long-term wastewater
irrigation of vegetables in real agricultural systems: concentration of pharmaceuticals in soil,
uptake and bioaccumulation in tomato fruits and human health risk assessment. Water Res
109:24–34
30. Facey SJ, Nebel BA, Kontny L, Allgaier M, Hauer B (2018) Rapid and complete degradation of
diclofenac by native soil microorganisms. Environ Technol Innov 10:55–61. https://doi.org/10.
1016/j.eti.2017.12.009
31. Durán-Alvarez JC, Becerril-Bravo E, Silva Castro V, Jiménez B, Gibson R (2009) The analysis
of a group of acidic pharmaceuticals, carbamazepine, and potential endocrine disrupting
compounds in wastewater irrigated soils by gas chromatography–mass spectrometry. Talanta
78:1159–1166
32. Vulava VM, Cory WC, Murphey VL, Ulmer CZ (2016) Sorption, photodegradation, and
chemical transformation of naproxen and ibuprofen in soils and water. Sci Total Environ
565:1063–1070
33. Gibson R, Durán-Alvarez JC, Estrada KL, Chávez A, Cisneros BJ (2010) Accumulation and
leaching potential of some pharmaceuticals and potential endocrine disruptors in soils irrigated
with wastewater in the Tula Valley, Mexico. Chemosphere 81:1437–1445
34. Grossberger A, Hadar Y, Borch T, Chefetz B (2014) Biodegradability of pharmaceutical
compounds in agricultural soils irrigated with treated wastewater. Environ Pollut 185:168–177
35. Koda O, Golovko O, Kodešová R, Klement A, Grabic R (2016) Transformation of atenolol,
metoprolol, and carbamazepine in soils: the identification, quantification, and stability of the
transformation products and further implications for the environment. Environ Pollut
218:574–585
36. Li J, Dodgen L, Ye Q, Gan J (2013) Degradation kinetics and metabolites of carbamazepine in
soil. Environ Sci Technol 47:3678–3684
37. Martínez-Hernández V, Meffe R, López SH, de Bustamante I (2016) The role of sorption and
biodegradation in the removal of acetaminophen, carbamazepine, caffeine, naproxen and
sulfamethoxazole during soil contact: a kinetic study. Sci Total Environ 559:232–241
38. Koba O, Golovko O, Kodešová R, Fér M, Grabic R (2017) Antibiotics degradation in soil: a
case of clindamycin, trimethoprim, sulfamethoxazole and their transformation products. Environ Pollut 220:1251–1263. https://doi.org/10.1016/j.envpol.2016.11.007
39. Girardi C, Greve J, Lamshöft M, Fetzer I, Miltner A, Schäffer A, Kästner M (2011) Biodegradation of ciprofloxacin in water and soil and its effects on the microbial communities. J
Hazard Mater 198:22–30
40. Butler E, Whelan MJ, Sakrabani R, van Egmond R (2012) Fate of triclosan in field soils
receiving sewage sludge. Environ Pollut 167:101–109
41. Biel-Maeso M, González-González C, Lara-Martín PA, Corada-Fernández C (2019) Sorption
and degradation of contaminants of emerging concern in soils under aerobic and anaerobic
conditions. Sci Total Environ 666:662–671
Soil Sorption and Degradation Studies of Pharmaceutical Compounds Present in. . .
171
human pharmaceuticals in the world’s largest wastewater irrigation system, Mexico CityMezquital Valley. Water Res 42:2124–2134
25. Biel-Maeso M, Corada-Fernández C, Lara-Martín PA (2018) Monitoring the occurrence of
pharmaceuticals in soils irrigated with reclaimed wastewater. Environ Pollut 235:312–321
26. Li J, Dodgen L, Ye Q, Gan J (2014) Degradation and transformation products of acetaminophen
in soil. Water Res 49:44–52
27. Corada-Fernández C, Jiménez-Martínez J, Candela L, González-Mazo E, Lara-Martín PA
(2015) Occurrence and spatial distribution of emerging contaminants in the unsaturated zone.
Case study: Guadalete River basin (Cadiz, Spain). Chemosphere 119:s131–s137
28. Dalkmann P, Broszat M, Siebe C, Willaschek E, Sakinc T, Huebner J, Amelung W,
Grohmann E, Siemens J (2012) Accumulation of pharmaceuticals, enterococcus, and resistance
genes in soils irrigated with wastewater for zero to 100 years in Central Mexico. PLoS One 7(9):
e45397
29. Christou A, Karaolia P, Hapeshi E, Michael C, Fatta-Kassinos D (2017) Long-term wastewater
irrigation of vegetables in real agricultural systems: concentration of pharmaceuticals in soil,
uptake and bioaccumulation in tomato fruits and human health risk assessment. Water Res
109:24–34
30. Facey SJ, Nebel BA, Kontny L, Allgaier M, Hauer B (2018) Rapid and complete degradation of
diclofenac by native soil microorganisms. Environ Technol Innov 10:55–61. https://doi.org/10.
1016/j.eti.2017.12.009
31. Durán-Alvarez JC, Becerril-Bravo E, Silva Castro V, Jiménez B, Gibson R (2009) The analysis
of a group of acidic pharmaceuticals, carbamazepine, and potential endocrine disrupting
compounds in wastewater irrigated soils by gas chromatography–mass spectrometry. Talanta
78:1159–1166
32. Vulava VM, Cory WC, Murphey VL, Ulmer CZ (2016) Sorption, photodegradation, and
chemical transformation of naproxen and ibuprofen in soils and water. Sci Total Environ
565:1063–1070
33. Gibson R, Durán-Alvarez JC, Estrada KL, Chávez A, Cisneros BJ (2010) Accumulation and
leaching potential of some pharmaceuticals and potential endocrine disruptors in soils irrigated
with wastewater in the Tula Valley, Mexico. Chemosphere 81:1437–1445
34. Grossberger A, Hadar Y, Borch T, Chefetz B (2014) Biodegradability of pharmaceutical
compounds in agricultural soils irrigated with treated wastewater. Environ Pollut 185:168–177
35. Koda O, Golovko O, Kodešová R, Klement A, Grabic R (2016) Transformation of atenolol,
metoprolol, and carbamazepine in soils: the identification, quantification, and stability of the
transformation products and further implications for the environment. Environ Pollut
218:574–585
36. Li J, Dodgen L, Ye Q, Gan J (2013) Degradation kinetics and metabolites of carbamazepine in
soil. Environ Sci Technol 47:3678–3684
37. Martínez-Hernández V, Meffe R, López SH, de Bustamante I (2016) The role of sorption and
biodegradation in the removal of acetaminophen, carbamazepine, caffeine, naproxen and
sulfamethoxazole during soil contact: a kinetic study. Sci Total Environ 559:232–241
38. Koba O, Golovko O, Kodešová R, Fér M, Grabic R (2017) Antibiotics degradation in soil: a
case of clindamycin, trimethoprim, sulfamethoxazole and their transformation products. Environ Pollut 220:1251–1263. https://doi.org/10.1016/j.envpol.2016.11.007
39. Girardi C, Greve J, Lamshöft M, Fetzer I, Miltner A, Schäffer A, Kästner M (2011) Biodegradation of ciprofloxacin in water and soil and its effects on the microbial communities. J
Hazard Mater 198:22–30
40. Butler E, Whelan MJ, Sakrabani R, van Egmond R (2012) Fate of triclosan in field soils
receiving sewage sludge. Environ Pollut 167:101–109
41. Biel-Maeso M, González-González C, Lara-Martín PA, Corada-Fernández C (2019) Sorption
and degradation of contaminants of emerging concern in soils under aerobic and anaerobic
conditions. Sci Total Environ 666:662–671
Soil Sorption and Degradation Studies of Pharmaceutical Compounds Present in. . .
171