29. Collins CD, Finnegan E (2010) Modeling the plant uptake of organic chemicals, including the
soil – air – plant pathway. Environ Sci Technol 44:998–1003. https://doi.org/10.1021/
es901941z
30. Schröder P, Collins C (2011) Organic xenobiotics and plants – from mode of action to
ecophysiology. Springer, Berlin. https://doi.org/10.1007/978-90-481-9852-8
31. Crang R, Lyons-Sobaski S, Wise R, Crang R, Lyons-Sobaski S, Wise R (2018) Periderm. In:
Plant anatomy. Springer, Cham, pp 553–575. https://doi.org/10.1007/978-3-319-77315-5_16
32. Trapp S, Pussemier L (1991) Model calculations and measurements of uptake and translocation of carbamates by bean plants. Chemosphere 22:327–339. https://doi.org/10.1016/00456535(91)90321-4
33. Collins CD, Martin I, Doucette W (2011) Plant uptake of xenobiotics. Springer, Dordrecht, pp
3–16. https://doi.org/10.1007/978-90-481-9852-8_1
34. Zhang C, Feng Y, Wang LY, Qing CH, Jun LZ, Ming XJ (2017) Uptake and translocation of
organic pollutants in plants: a review. J Integr Agric 16:1659–1668. https://doi.org/10.1016/
S2095-3119(16)61590-3
35. Eggen T, Asp TN, Grave K, Hormazabal V (2011) Uptake and translocation of metformin,
ciprofloxacin and narasin in forage- and crop plants. Chemosphere 85:26–33. https://doi.org/
10.1016/j.chemosphere.2011.06.041
36. González García M, Fernández-López C, Polesel F, Trapp S (2019) Predicting the uptake of
emerging organic contaminants in vegetables irrigated with treated wastewater – implications
for food safety assessment. Environ Res 172:175–181. https://doi.org/10.1016/j.envres.2019.
02.011
37. Trapp S (2009) Bioaccumulation of polar and ionizable compounds in plants. Springer,
Boston, pp 299–353. https://doi.org/10.1007/978-1-4419-0197-2_11
38. Kumar K, Gupta SC (2016) A framework to predict uptake of trace organic compounds by
plants. J Environ Qual 45:555–564. https://doi.org/10.2134/jeq2015.06.0261
39. Su YH, Zhu YG (2007) Transport mechanisms for the uptake of organic compounds by rice
(Oryza sativa) roots. Environ Pollut 148:94–100. https://doi.org/10.1016/j.envpol.2006.11.
004
40. Volk C (2014) OCTs, OATs, and OCTNs: structure and function of the polyspecific organic
ion transporters of the SLC22 family. Wiley Interdiscip Rev Membr Transp Signal 3:1–13.
https://doi.org/10.1002/wmts.100
41. Lalonde S, Wipf D, Frommer WB (2004) Transport mechanism for organic forms of carbon
and nitrogen between source and sink. Annu Rev Plant Biol 55:341–372. https://doi.org/10.
1146/annurev.arplant.55.031903.141758
42. Gründemann D, Gorboulev V, Gambaryan S, Veyhl M, Koepsell H (1994) Drug excretion
mediated by a new prototype of polyspecific transporter. Nature 372:549–552. https://doi.org/
10.1038/372549a0
43. Koepsell H, Endou H (2004) The SLC22 drug transporter family. Pflugers Arch Eur J Physiol
447:666–676. https://doi.org/10.1007/s00424-003-1089-9
44. Takanashi K, Shitan N, Yazaki K (2014) The multidrug and toxic compound extrusion
(MATE) family in plants. Plant Biotechnol 31:417–430
45. Diener AC, Gaxiola RA, Fink GR (2001) Arabidopsis ALF5, a multidrug efflux transporter
gene family member, confers resistance to toxins. Plant Cell 13:1625–1638. https://doi.org/10.
1105/tpc.010035
46. Li L, He Z, Pandey GK, Tsuchiya T, Luan S (2002) Functional cloning and characterization of
a plant efflux carrier for multidrug and heavy metal detoxification. J Biol Chem
277:5360–5368. https://doi.org/10.1074/jbc.M108777200
47. Torres GAM, Lelandais-Brière C, Besin E, Jubier MF, Roche O, Mazubert C, Corre-MenguyF, Hartmann C (2003) Characterization of the expression of Phaseolus vulgaris OCT1, a
dehydration-regulated gene that encodes a new type of phloem transporter. Plant Mol Biol
51:341–349. https://doi.org/10.1023/A:1022014229899
134
Y. Bigott et al.
soil – air – plant pathway. Environ Sci Technol 44:998–1003. https://doi.org/10.1021/
es901941z
30. Schröder P, Collins C (2011) Organic xenobiotics and plants – from mode of action to
ecophysiology. Springer, Berlin. https://doi.org/10.1007/978-90-481-9852-8
31. Crang R, Lyons-Sobaski S, Wise R, Crang R, Lyons-Sobaski S, Wise R (2018) Periderm. In:
Plant anatomy. Springer, Cham, pp 553–575. https://doi.org/10.1007/978-3-319-77315-5_16
32. Trapp S, Pussemier L (1991) Model calculations and measurements of uptake and translocation of carbamates by bean plants. Chemosphere 22:327–339. https://doi.org/10.1016/00456535(91)90321-4
33. Collins CD, Martin I, Doucette W (2011) Plant uptake of xenobiotics. Springer, Dordrecht, pp
3–16. https://doi.org/10.1007/978-90-481-9852-8_1
34. Zhang C, Feng Y, Wang LY, Qing CH, Jun LZ, Ming XJ (2017) Uptake and translocation of
organic pollutants in plants: a review. J Integr Agric 16:1659–1668. https://doi.org/10.1016/
S2095-3119(16)61590-3
35. Eggen T, Asp TN, Grave K, Hormazabal V (2011) Uptake and translocation of metformin,
ciprofloxacin and narasin in forage- and crop plants. Chemosphere 85:26–33. https://doi.org/
10.1016/j.chemosphere.2011.06.041
36. González García M, Fernández-López C, Polesel F, Trapp S (2019) Predicting the uptake of
emerging organic contaminants in vegetables irrigated with treated wastewater – implications
for food safety assessment. Environ Res 172:175–181. https://doi.org/10.1016/j.envres.2019.
02.011
37. Trapp S (2009) Bioaccumulation of polar and ionizable compounds in plants. Springer,
Boston, pp 299–353. https://doi.org/10.1007/978-1-4419-0197-2_11
38. Kumar K, Gupta SC (2016) A framework to predict uptake of trace organic compounds by
plants. J Environ Qual 45:555–564. https://doi.org/10.2134/jeq2015.06.0261
39. Su YH, Zhu YG (2007) Transport mechanisms for the uptake of organic compounds by rice
(Oryza sativa) roots. Environ Pollut 148:94–100. https://doi.org/10.1016/j.envpol.2006.11.
004
40. Volk C (2014) OCTs, OATs, and OCTNs: structure and function of the polyspecific organic
ion transporters of the SLC22 family. Wiley Interdiscip Rev Membr Transp Signal 3:1–13.
https://doi.org/10.1002/wmts.100
41. Lalonde S, Wipf D, Frommer WB (2004) Transport mechanism for organic forms of carbon
and nitrogen between source and sink. Annu Rev Plant Biol 55:341–372. https://doi.org/10.
1146/annurev.arplant.55.031903.141758
42. Gründemann D, Gorboulev V, Gambaryan S, Veyhl M, Koepsell H (1994) Drug excretion
mediated by a new prototype of polyspecific transporter. Nature 372:549–552. https://doi.org/
10.1038/372549a0
43. Koepsell H, Endou H (2004) The SLC22 drug transporter family. Pflugers Arch Eur J Physiol
447:666–676. https://doi.org/10.1007/s00424-003-1089-9
44. Takanashi K, Shitan N, Yazaki K (2014) The multidrug and toxic compound extrusion
(MATE) family in plants. Plant Biotechnol 31:417–430
45. Diener AC, Gaxiola RA, Fink GR (2001) Arabidopsis ALF5, a multidrug efflux transporter
gene family member, confers resistance to toxins. Plant Cell 13:1625–1638. https://doi.org/10.
1105/tpc.010035
46. Li L, He Z, Pandey GK, Tsuchiya T, Luan S (2002) Functional cloning and characterization of
a plant efflux carrier for multidrug and heavy metal detoxification. J Biol Chem
277:5360–5368. https://doi.org/10.1074/jbc.M108777200
47. Torres GAM, Lelandais-Brière C, Besin E, Jubier MF, Roche O, Mazubert C, Corre-MenguyF, Hartmann C (2003) Characterization of the expression of Phaseolus vulgaris OCT1, a
dehydration-regulated gene that encodes a new type of phloem transporter. Plant Mol Biol
51:341–349. https://doi.org/10.1023/A:1022014229899
134
Y. Bigott et al.