cat. Pd
anodic oxidation
Me BF 3 K
Ph
CO 2 H
O
N
OMe
R
N
OMe
R
N
OMe
R
Me
Ph
O
Scheme 83 C(sp
2
)–H couplings via anodic oxidation
cat. Co(OAc)2 4H 2 O
NaOPiv, 6h, RT
R OH
RVC
Pt
N
H
O
PyO
Ar
N
H
O
PyO
Ar
OR
Scheme 84 Electrochemical C−H oxygenation
NaI (0.5 equiv)
Amberlyst 15(H)
®
EtOH/DMSO/H 2 O
CCE, undivided cell
Het SH
NaSCN
R 1
O
R 3
R 2
or
R 1
O
R 3
R 2
R 1
O
R 3
R 2
SCN
S Het
or
Scheme 85 Electrochemical oxidative α-thiocyanation of different ketones
Cp*RhCl2 2 (2.5 mol%)
KOAc
t-AmOH/H 2 O (3/ 1 )
100
o C, 5-18 h
undivided cell, CCE at 4.0 mA
RVC
Pt
X
O
H
Ar
Ar
R
X
O
R
X = O, NR
Scheme 86 Rhodium-catalysed electrooxidative twofold C–H/C–H alkenylation
cat. Ni(DME)Cl2
nBu 4 NBF 4 , NaOPiv
DMA, 120-130
o C, 10-16 h
undivided cell, CCE at 8.0 mA
RVC
Ni foam
N
H
O
Q
Ar
N
H
R 2
R 1
N
H
O
Q
Ar
N
R 1
R 2
Scheme 87 Ni-catalysed electrooxidative C–H amination reaction with amines