272
O
RhCp*Cl2 2 (1.0 mol%)
CsOAc (30 mol%)
MeOH (0.2 M),
60
o
C, 3-16 h
N
H
OMe
R 1
O
NH 2
R 1
R 2
R 2
Scheme 20 Rh(III)-catalysed olefination using N-methoxybenzamides directing group
RhCp*Cl2 2 (2.5 mol%)
AgSbF6 (10 mol%)
CsOPiv (30 mol%)
PivOH (2 equiv),
MeOH, RT, N 2 , 24 h
R
CO 2 Et
N
R 1
R 2
O
R
N
R 1
R 2
CO 2 Et
Scheme 21 N-oxides assisted C–H olefination reaction
RhCp*Cl2 2 (4 mol%)
AgSbF6 (16 mol%)
AcOH (2 equiv),
1,4-dioxane, 110
o
C, 20 h
N
O
Ar
R
N
R
Ar
O
Scheme 22 N–O bond as an internal oxidant for Rh(III)-catalysed access of substituted
acetophenones
RhCp*Cl2 2 (1 mol%)
CsOPiv (0.3 equiv)
PivOH (1.0 equiv),
TFE, 80
o C, 18 h
R 2
R 3
O
O
R 1
R 1
O
O
R 3
R 2
O
Scheme 23 Peresters as an oxidizing directing group for the redox-neutral access of
isocoumarins
RhCp*(OAc)2 (8 mol%)
MeOH,
90
o
C
R 4
R 3
N N
O
R 2
R 1
R 1
N
R 4
R 3
R 2
Scheme 24 Rh(III)-catalysed synthesis of indoles using N–N bond as an internal oxidizing agent
D. S. Deshmukh et al.