253
© Springer Nature Switzerland AG 2021
K. K. Pant et al. (eds.), Catalysis for Clean Energy and Environmental
Sustainability, https://doi.org/10.1007/978-3-030-65021-6_8
Insights into Sustainable C–H Bond
Activation
Dewal S. Deshmukh, Vaishali S. Shende, and Bhalchandra M. Bhanage
Abstract Over the recent past, the straight functionalization of inert C–H bond has
already been identified as an advanced technique for the synthesis of organic molecules. It has provided a step-, pot- and atom-economic synthetic approach to attain
structurally challenging organic scaffolds using simpler, pre-functionalized substrates by single operation and thereby arisen as a sustainable substitution to traditional organic transformations. Regardless of the clear evolution and improvements
in metal-catalysed C–H functionalization reactions, these kinds of conversions quiet
face considerable restrictions with respect to green chemistry regarding the catalyst
reusability, media, time efficiency, energy efficiency, byproducts, requirement of
additives as well as oxidants. Encouraged with the necessity for green and sustainable chemistry, researchers attempt further effective routes in this area for the construction of organic scaffolds. Recently, distinguished achievements were attained
with the expansion of sustainable methodologies in C–H activation reactions. The
attention of the book section is to summarize the progress of greener methodologies
for C–H functionalization reactions which incorporate applications of greener solvents, microwave irradiation, photocatalysis, homogeneous recyclable catalytic systems, heterogeneous catalysts, oxidizing directing groups, electrochemical methods,
etc., during the past few years. The book chapter emphasizes selected fascinating
and encouraging examples of greener methodologies in C–H activation approaches.
Keywords C–H activation · Green-chemistry · Catalysis
D. S. Deshmukh
Department of Chemistry, Shri Shivaji Arts, Commerce and Science College, Akola, India
V. S. Shende · B. M. Bhanage (*)
Department of Chemistry, Institute of Chemical Technology, Mumbai, India
e-mail: bm.bhanage@ictmumbai.edu.in
© Springer Nature Switzerland AG 2021
K. K. Pant et al. (eds.), Catalysis for Clean Energy and Environmental
Sustainability, https://doi.org/10.1007/978-3-030-65021-6_8
Insights into Sustainable C–H Bond
Activation
Dewal S. Deshmukh, Vaishali S. Shende, and Bhalchandra M. Bhanage
Abstract Over the recent past, the straight functionalization of inert C–H bond has
already been identified as an advanced technique for the synthesis of organic molecules. It has provided a step-, pot- and atom-economic synthetic approach to attain
structurally challenging organic scaffolds using simpler, pre-functionalized substrates by single operation and thereby arisen as a sustainable substitution to traditional organic transformations. Regardless of the clear evolution and improvements
in metal-catalysed C–H functionalization reactions, these kinds of conversions quiet
face considerable restrictions with respect to green chemistry regarding the catalyst
reusability, media, time efficiency, energy efficiency, byproducts, requirement of
additives as well as oxidants. Encouraged with the necessity for green and sustainable chemistry, researchers attempt further effective routes in this area for the construction of organic scaffolds. Recently, distinguished achievements were attained
with the expansion of sustainable methodologies in C–H activation reactions. The
attention of the book section is to summarize the progress of greener methodologies
for C–H functionalization reactions which incorporate applications of greener solvents, microwave irradiation, photocatalysis, homogeneous recyclable catalytic systems, heterogeneous catalysts, oxidizing directing groups, electrochemical methods,
etc., during the past few years. The book chapter emphasizes selected fascinating
and encouraging examples of greener methodologies in C–H activation approaches.
Keywords C–H activation · Green-chemistry · Catalysis
D. S. Deshmukh
Department of Chemistry, Shri Shivaji Arts, Commerce and Science College, Akola, India
V. S. Shende · B. M. Bhanage (*)
Department of Chemistry, Institute of Chemical Technology, Mumbai, India
e-mail: bm.bhanage@ictmumbai.edu.in