510
Diabetics
benefits, 454
Diabetogen, 138
Diabetogenesis, 229
Dibutyl phthalate (DBP), 118
Dichlorodiphenyltrichloroethane (DDT), 118,
266–269, 277, 279
Dichloromethane, 412, 417
Dietary fats, 398, 399
Dietary fibers, 405
Dietary lipids, 90
Diethylhexylphthalate (DEHP), 240, 242–244,
246, 247
Difurocoumarocyclopentenone, 382
Difurocoumarolactone, 382
Dihydroxyacetone phosphate (DAP), 47
Diuretics, 363
Ductless hormonal system, 457
Dynamic light scattering (DLS), 426
Dyslipidemia, 168, 192, 385
Dysregulation, 141
E
EDCs-induced diabetes mellitus
and hyperglycemia, 138
liver cells, 138
and metabolic disorders, 138
EDCs-induced obesity
chemical signaling functions, 137
DES exposure, 138
PPARɣ agonist medications, 137
type II diabetes, 137
Electron microscopy-based techniques, 425
Emulsification-solvent displacement, 415
Emulsification-solvent evaporation technique,
412, 413
Endocrinal signaling, 247, 248
Endocrinal system, 222
Endocrine disrupting chemicals (EDCs),
136, 491
common EDCS, 358, 359
as endocrine-modulators/disruptors, 358
parabens effect (see Parabens)
Endocrine disrupting compounds (EDCs), 176
Endocrine-disrupting chemicals (EDCs), 114,
115, 148, 204
adipocyte formation pathways, 228
androgens, 118
antibiotics, 126
BPA, 118 (see Bisphenol A (BPA))
categories, 115
chemicals, 126
childhood obesity
basis of occurrence, 148
basis of origin, 149
BMI, 153
BPA, 153
characteristics, 149
DDT, 153
epigenetic alterations, 150
epigenetics, 150
exposure, 154
features, 156
hormone production, 150
humans and animals, 157
mechanisms, 150
phthalates, 153
toxic effects, 156
contaminant exposure rates, 121
DDT, 118
definition, 324
endocrine-disrupting compounds, 115
on endocrine system, 324–325
exogenous chemicals, 126
exposure, 119, 120, 126
e-waste, 120
FRs (see Flame-retardants (FRs))
and human exposure, 119
industrial regions, 115
industrialization, 115
obesity, 126
origin, 117
PAHs effect (see Polycyclic aromatic
hydrocarbons (PAHs))
pesticide, 120
pharmaceutical exposure, 120
phthalates, 118
sources, 117
synthetic chemicals, 117
use, 114
xenobiotic compounds, 114
Endocrine disruption
by FRs, 226, 227
disruptor, defined, 226
dose–response, 227
EDCs, 226
environment, indoors and outdoors, 226
exogenous substances, 226
exposure to EDCs, 227
obesity and diabetes, 227–230
oxidative stress and inflammatory
responses, 230–232
obesity and diabetes, 222
Endocrine disruptors, 114, 136, 148, 324
definition, 226
as exogenous substances, 226
Endocrine glands
Index
Diabetics
benefits, 454
Diabetogen, 138
Diabetogenesis, 229
Dibutyl phthalate (DBP), 118
Dichlorodiphenyltrichloroethane (DDT), 118,
266–269, 277, 279
Dichloromethane, 412, 417
Dietary fats, 398, 399
Dietary fibers, 405
Dietary lipids, 90
Diethylhexylphthalate (DEHP), 240, 242–244,
246, 247
Difurocoumarocyclopentenone, 382
Difurocoumarolactone, 382
Dihydroxyacetone phosphate (DAP), 47
Diuretics, 363
Ductless hormonal system, 457
Dynamic light scattering (DLS), 426
Dyslipidemia, 168, 192, 385
Dysregulation, 141
E
EDCs-induced diabetes mellitus
and hyperglycemia, 138
liver cells, 138
and metabolic disorders, 138
EDCs-induced obesity
chemical signaling functions, 137
DES exposure, 138
PPARɣ agonist medications, 137
type II diabetes, 137
Electron microscopy-based techniques, 425
Emulsification-solvent displacement, 415
Emulsification-solvent evaporation technique,
412, 413
Endocrinal signaling, 247, 248
Endocrinal system, 222
Endocrine disrupting chemicals (EDCs),
136, 491
common EDCS, 358, 359
as endocrine-modulators/disruptors, 358
parabens effect (see Parabens)
Endocrine disrupting compounds (EDCs), 176
Endocrine-disrupting chemicals (EDCs), 114,
115, 148, 204
adipocyte formation pathways, 228
androgens, 118
antibiotics, 126
BPA, 118 (see Bisphenol A (BPA))
categories, 115
chemicals, 126
childhood obesity
basis of occurrence, 148
basis of origin, 149
BMI, 153
BPA, 153
characteristics, 149
DDT, 153
epigenetic alterations, 150
epigenetics, 150
exposure, 154
features, 156
hormone production, 150
humans and animals, 157
mechanisms, 150
phthalates, 153
toxic effects, 156
contaminant exposure rates, 121
DDT, 118
definition, 324
endocrine-disrupting compounds, 115
on endocrine system, 324–325
exogenous chemicals, 126
exposure, 119, 120, 126
e-waste, 120
FRs (see Flame-retardants (FRs))
and human exposure, 119
industrial regions, 115
industrialization, 115
obesity, 126
origin, 117
PAHs effect (see Polycyclic aromatic
hydrocarbons (PAHs))
pesticide, 120
pharmaceutical exposure, 120
phthalates, 118
sources, 117
synthetic chemicals, 117
use, 114
xenobiotic compounds, 114
Endocrine disruption
by FRs, 226, 227
disruptor, defined, 226
dose–response, 227
EDCs, 226
environment, indoors and outdoors, 226
exogenous substances, 226
exposure to EDCs, 227
obesity and diabetes, 227–230
oxidative stress and inflammatory
responses, 230–232
obesity and diabetes, 222
Endocrine disruptors, 114, 136, 148, 324
definition, 226
as exogenous substances, 226
Endocrine glands
Index