219
67. Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 and 2. Ann Rev Pharmacol Toxicol.
1998;38:97–120.
68. Wei J, Du K, Cai Q, Ma L, Jiao Z, Tan J, et al. Lead induces COX-2 expression in glial cells in
a NFAT-dependent, AP-1/NFkappaB-independent manner. Toxicology. 2014;325:67–73.
69. Metryka E, Chibowska K, Gutowska I, Falkowska A, Kupnicka P, Barczak K, et al. Lead
(Pb) exposure enhances expression of factors associated with inflammation. Int J Mol Sci.
2018;19(6):1813.
70. Cai L, Li XK, Song Y, Cherian MG. Essentiality, toxicology and chelation therapy of zinc and
copper. Curr Med Chem. 2005;12(23):2753–63.
71. Wang S, Liu GC, Wintergerst KA, Cai L. Chapter 14 - Metals in diabetes: zinc homeostasis in
the metabolic syndrome and diabetes. In: Mauricio D, editor. Molecular nutrition and diabetes.
San Diego: Academic Press; 2016. p. 169–82.
72. Olechnowicz J, Tinkov A, Skalny A, Suliburska J. Zinc status is associated with inflammation,
oxidative stress, lipid, and glucose metabolism. J Physiol Sci. 2018;68(1):19–31.
73. Hopps E, Noto D, Caimi G, Averna MR. A novel component of the metabolic syndrome: the
oxidative stress. Nutr Metab Cardiovasc Dis. 2010;20(1):72–7.
74. Ogawa D, Asanuma M, Miyazaki I, Tachibana H, Wada J, Sogawa N, et al. High glucose
increases metallothionein expression in renal proximal tubular epithelial cells. Exp Diabetes
Res. 2011;2011:534872.
75. Hadwan MH, Almashhedy LA, Alsalman AR. Study of the effects of oral zinc supplementation on peroxynitrite levels, arginase activity and NO synthase activity in seminal plasma of
Iraqi asthenospermic patients. Reprod Biol Endocrinol. 2014;12:1.
76. Saarni H, Tamminen-Peter L. Physical stress and strain in catering work on the Baltic car ferries. Bull Inst Marit Trop Med Gdynia. 1987;38(1–2):25–31.
77. Payahoo L, Ostadrahimi A, Mobasseri M, Khajebishak Y, Asghari Jafarabadi M. Effects of
zinc supplementation on serum leptin level and insulin sensitivity in obese people. Trace Elem
Electrolytes. 2014;31:27–32.
78. Baltaci AK, Mogulkoc R. Leptin and zinc relation: In regulation of food intake and immunity.
Indian J Endocrinol Metab. 2012;16(Suppl 3):S611–6.
79. Briggs DB, Giron RM, Schnittker K, Hart MV, Park CK, Hausrath AC, et al. Zinc enhances
adiponectin oligomerization to octadecamers but decreases the rate of disulfide bond formation. Biometals: Int J Role Metal Ions Biol Biochem Med. 2012;25(2):469–86.
80. Mazloomi S, Alizadeh N, Aminzare M, Niroomand S, Mousavi SN. Retracted article: serum
zinc and adiponectin levels in patients with polycystic ovary syndrome, adjusted for anthropometric, biochemical, dietary intake, and physical activity measures. Biol Trace Element Res.
2018;181(2):388.
13 Role of Heavy Metals in Metabolic Disorders
67. Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 and 2. Ann Rev Pharmacol Toxicol.
1998;38:97–120.
68. Wei J, Du K, Cai Q, Ma L, Jiao Z, Tan J, et al. Lead induces COX-2 expression in glial cells in
a NFAT-dependent, AP-1/NFkappaB-independent manner. Toxicology. 2014;325:67–73.
69. Metryka E, Chibowska K, Gutowska I, Falkowska A, Kupnicka P, Barczak K, et al. Lead
(Pb) exposure enhances expression of factors associated with inflammation. Int J Mol Sci.
2018;19(6):1813.
70. Cai L, Li XK, Song Y, Cherian MG. Essentiality, toxicology and chelation therapy of zinc and
copper. Curr Med Chem. 2005;12(23):2753–63.
71. Wang S, Liu GC, Wintergerst KA, Cai L. Chapter 14 - Metals in diabetes: zinc homeostasis in
the metabolic syndrome and diabetes. In: Mauricio D, editor. Molecular nutrition and diabetes.
San Diego: Academic Press; 2016. p. 169–82.
72. Olechnowicz J, Tinkov A, Skalny A, Suliburska J. Zinc status is associated with inflammation,
oxidative stress, lipid, and glucose metabolism. J Physiol Sci. 2018;68(1):19–31.
73. Hopps E, Noto D, Caimi G, Averna MR. A novel component of the metabolic syndrome: the
oxidative stress. Nutr Metab Cardiovasc Dis. 2010;20(1):72–7.
74. Ogawa D, Asanuma M, Miyazaki I, Tachibana H, Wada J, Sogawa N, et al. High glucose
increases metallothionein expression in renal proximal tubular epithelial cells. Exp Diabetes
Res. 2011;2011:534872.
75. Hadwan MH, Almashhedy LA, Alsalman AR. Study of the effects of oral zinc supplementation on peroxynitrite levels, arginase activity and NO synthase activity in seminal plasma of
Iraqi asthenospermic patients. Reprod Biol Endocrinol. 2014;12:1.
76. Saarni H, Tamminen-Peter L. Physical stress and strain in catering work on the Baltic car ferries. Bull Inst Marit Trop Med Gdynia. 1987;38(1–2):25–31.
77. Payahoo L, Ostadrahimi A, Mobasseri M, Khajebishak Y, Asghari Jafarabadi M. Effects of
zinc supplementation on serum leptin level and insulin sensitivity in obese people. Trace Elem
Electrolytes. 2014;31:27–32.
78. Baltaci AK, Mogulkoc R. Leptin and zinc relation: In regulation of food intake and immunity.
Indian J Endocrinol Metab. 2012;16(Suppl 3):S611–6.
79. Briggs DB, Giron RM, Schnittker K, Hart MV, Park CK, Hausrath AC, et al. Zinc enhances
adiponectin oligomerization to octadecamers but decreases the rate of disulfide bond formation. Biometals: Int J Role Metal Ions Biol Biochem Med. 2012;25(2):469–86.
80. Mazloomi S, Alizadeh N, Aminzare M, Niroomand S, Mousavi SN. Retracted article: serum
zinc and adiponectin levels in patients with polycystic ovary syndrome, adjusted for anthropometric, biochemical, dietary intake, and physical activity measures. Biol Trace Element Res.
2018;181(2):388.
13 Role of Heavy Metals in Metabolic Disorders