201
66. Smith RC, Southwell-Keely J, Chesher D. Should serum pancreatic lipase replace serum
amylase as a biomarker of acute pancreatitis? ANZ J Surg. 2005;75(6):399–404.
67. Dere E, Ferda O, Tosunoglu H. Hepatotoxicity of Dinitro-o-cresol in rats (Rattus norvegicus).
Acta Vet Brno. 2007;57:5.
68. Maronpot RR, Giles HD, Dykes DJ, Irwin RD. Furan-induced hepatic cholangiocarcinomas
in Fischer 344 rats. Toxicol Pathol. 1991;19(4–2):561–70.
69. Program NT. Toxicology and carcinogenesis studies of furan (CAS No. 110-00-9) in F344
rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser. 1993;402:1.
70. Jun H-j, Lee K-G, Lee Y-K, Woo G-J, Park YS, Lee S-J. Correlation of urinary furan with
plasma γ-glutamyltranspeptidase levels in healthy men and women. Food Chem Toxicol.
2008;46(5):1753–9.
71. de Conti A, Tryndyak V, Doerge DR, Beland FA, Pogribny IP. Irreversible down-regulation of
miR-375 in the livers of Fischer 344 rats after chronic furan exposure. Food Chem Toxicol.
2016;98:2–10.
72. Edwards SG, Kennedy MC, O’Hagan S, O’Mahony C, Scholz G, Steinberg P, et al. A framework to determine the effectiveness of dietary exposure mitigation to chemical contaminants.
Food Chem Toxicol. 2014;74:360–71.
73. Mugford CA, Carfagna MA, Kedderis GL. Furan-mediated uncoupling of hepatic oxidative
phosphorylation in Fischer-344 rats: an early event in cell death. Toxicol Appl Pharmacol.
1997;144(1):1–11.
74. Leopardi P, Cordelli E, Villani P, Cremona TP, Conti L, De Luca G, et al. Assessment of
in vivo genotoxicity of the rodent carcinogen furan: evaluation of DNA damage and induction of micronuclei in mouse splenocytes. Mutagenesis. 2009;25(1):57–62.
75. Jestoi M, Järvinen T, Järvenpää E, Tapanainen H, Virtanen S, Peltonen K. Furan in the
baby-food samples purchased from the Finnish markets—determination with SPME–GC–
MS. Food Chem. 2009;117(3):522–8.
76. Sujatha P. Monitoring cytotoxic potentials of furfuryl alcohol and 2-furyl methyl ketone in
mice. Food Chem Toxicol. 2008;46(1):286–92.
77. Altaki M, Santos F, Galceran M. Occurrence of furan in coffee from Spanish market: contribution of brewing and roasting. Food Chem. 2011;126(4):1527–32.
78. Wang E, Chen F, Hu X, Yuan Y. Protective effects of apigenin against furan-induced toxicity
in mice. Food Funct. 2014;5(8):1804–12.
79. Atkin M, Laight D, Cummings MH. The effects of garlic extract upon endothelial function,
vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at
high cardiovascular risk. A pilot double blind randomized placebo controlled trial. J Diabet
Complicat. 2016;30(4):723–7.
80. Campbell PT, Newton CC, Patel AV, Jacobs EJ, Gapstur SM. Diabetes and cause-specific mortality in a prospective cohort of one million US adults. Diabetes Care. 2012;35(9):1835–44.
81. Lü Q, Tong N, Liu Y, Li N, Tang X, Zhao J, et al. Community-based population data indicates the significant alterations of insulin resistance, chronic inflammation and urine ACR
in IFG combined IGT group among prediabetic population. Diabetes Res Clin Pract.
2009;84(3):319–24.
82. Perticone F, Maio R, Sciacqua A, Andreozzi F, Iemma G, Perticone M, et al. Endothelial
dysfunction and C-reactive protein are risk factors for diabetes in essential hypertension.
Diabetes. 2008;57(1):167–71.
83. Shanmugam KR, Mallikarjuna K, Nishanth K, Kuo CH, Reddy KS. Protective effect of
dietary ginger on antioxidant enzymes and oxidative damage in experimental diabetic rat
tissues. Food Chem. 2011;124(4):1436–42.
84. Suresh S, Prithiviraj E, Lakshmi NV, Ganesh MK, Ganesh L, Prakash S. Effect of Mucuna
pruriens (Linn.) on mitochondrial dysfunction and DNA damage in epididymal sperm of
streptozotocin induced diabetic rat. J Ethnopharmacol. 2013;145(1):32–41.
85. Hickling K, Hitchcock J, Oreffo V, Mally A, Hammond T, Evans J, et al. Evidence of oxidative stress and associated DNA damage, increased proliferative drive, and altered gene
12 Role of Furans as EDCs in Metabolic Disorders
66. Smith RC, Southwell-Keely J, Chesher D. Should serum pancreatic lipase replace serum
amylase as a biomarker of acute pancreatitis? ANZ J Surg. 2005;75(6):399–404.
67. Dere E, Ferda O, Tosunoglu H. Hepatotoxicity of Dinitro-o-cresol in rats (Rattus norvegicus).
Acta Vet Brno. 2007;57:5.
68. Maronpot RR, Giles HD, Dykes DJ, Irwin RD. Furan-induced hepatic cholangiocarcinomas
in Fischer 344 rats. Toxicol Pathol. 1991;19(4–2):561–70.
69. Program NT. Toxicology and carcinogenesis studies of furan (CAS No. 110-00-9) in F344
rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser. 1993;402:1.
70. Jun H-j, Lee K-G, Lee Y-K, Woo G-J, Park YS, Lee S-J. Correlation of urinary furan with
plasma γ-glutamyltranspeptidase levels in healthy men and women. Food Chem Toxicol.
2008;46(5):1753–9.
71. de Conti A, Tryndyak V, Doerge DR, Beland FA, Pogribny IP. Irreversible down-regulation of
miR-375 in the livers of Fischer 344 rats after chronic furan exposure. Food Chem Toxicol.
2016;98:2–10.
72. Edwards SG, Kennedy MC, O’Hagan S, O’Mahony C, Scholz G, Steinberg P, et al. A framework to determine the effectiveness of dietary exposure mitigation to chemical contaminants.
Food Chem Toxicol. 2014;74:360–71.
73. Mugford CA, Carfagna MA, Kedderis GL. Furan-mediated uncoupling of hepatic oxidative
phosphorylation in Fischer-344 rats: an early event in cell death. Toxicol Appl Pharmacol.
1997;144(1):1–11.
74. Leopardi P, Cordelli E, Villani P, Cremona TP, Conti L, De Luca G, et al. Assessment of
in vivo genotoxicity of the rodent carcinogen furan: evaluation of DNA damage and induction of micronuclei in mouse splenocytes. Mutagenesis. 2009;25(1):57–62.
75. Jestoi M, Järvinen T, Järvenpää E, Tapanainen H, Virtanen S, Peltonen K. Furan in the
baby-food samples purchased from the Finnish markets—determination with SPME–GC–
MS. Food Chem. 2009;117(3):522–8.
76. Sujatha P. Monitoring cytotoxic potentials of furfuryl alcohol and 2-furyl methyl ketone in
mice. Food Chem Toxicol. 2008;46(1):286–92.
77. Altaki M, Santos F, Galceran M. Occurrence of furan in coffee from Spanish market: contribution of brewing and roasting. Food Chem. 2011;126(4):1527–32.
78. Wang E, Chen F, Hu X, Yuan Y. Protective effects of apigenin against furan-induced toxicity
in mice. Food Funct. 2014;5(8):1804–12.
79. Atkin M, Laight D, Cummings MH. The effects of garlic extract upon endothelial function,
vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at
high cardiovascular risk. A pilot double blind randomized placebo controlled trial. J Diabet
Complicat. 2016;30(4):723–7.
80. Campbell PT, Newton CC, Patel AV, Jacobs EJ, Gapstur SM. Diabetes and cause-specific mortality in a prospective cohort of one million US adults. Diabetes Care. 2012;35(9):1835–44.
81. Lü Q, Tong N, Liu Y, Li N, Tang X, Zhao J, et al. Community-based population data indicates the significant alterations of insulin resistance, chronic inflammation and urine ACR
in IFG combined IGT group among prediabetic population. Diabetes Res Clin Pract.
2009;84(3):319–24.
82. Perticone F, Maio R, Sciacqua A, Andreozzi F, Iemma G, Perticone M, et al. Endothelial
dysfunction and C-reactive protein are risk factors for diabetes in essential hypertension.
Diabetes. 2008;57(1):167–71.
83. Shanmugam KR, Mallikarjuna K, Nishanth K, Kuo CH, Reddy KS. Protective effect of
dietary ginger on antioxidant enzymes and oxidative damage in experimental diabetic rat
tissues. Food Chem. 2011;124(4):1436–42.
84. Suresh S, Prithiviraj E, Lakshmi NV, Ganesh MK, Ganesh L, Prakash S. Effect of Mucuna
pruriens (Linn.) on mitochondrial dysfunction and DNA damage in epididymal sperm of
streptozotocin induced diabetic rat. J Ethnopharmacol. 2013;145(1):32–41.
85. Hickling K, Hitchcock J, Oreffo V, Mally A, Hammond T, Evans J, et al. Evidence of oxidative stress and associated DNA damage, increased proliferative drive, and altered gene
12 Role of Furans as EDCs in Metabolic Disorders