172
56. Kurita H, Yoshioka W, Nishimura N, Kubota N, Kadowaki T, Tohyama C. Aryl hydrocarbon
receptor-mediated effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on glucose-stimulated
insulin secretion in mice. J Appl Toxicol. 2009;29(8):689–94.
57. Novelli M, Piaggi S, De Tata V. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin-induced impairment of glucose-stimulated insulin secretion in isolated rat pancreatic islets. Toxicol Lett.
2005;156(2):307–14.
58. Wassermann D, Wassermann M, Lemesch C. Ultrastructure of beta-cells of the endocrine pancreas in rats receiving polychlorinated biphenyls. Environ Physiol Biochem.
1975;5(5):322–40.
59. Fischer LJ, Zhou H-R, Wagner MA. Polychlorinated biphenyls release insulin from RINm5F
cells. Life Sci. 1996;59(24):2041–9.
60. Kim Y-H, Shim Y-J, Shin Y-J, Sul D, Lee E, Min B-H. 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
(TCDD) induces calcium influx through T-type calcium channel and enhances lysosomal
exocytosis and insulin secretion in INS-1 cells. Int J Toxicol. 2009;28(3):151–61.
61. Wahlang B, Song M, Beier JI, Falkner KC, Al-Eryani L, Clair HB, et al. Evaluation of
Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty
liver disease. Toxicol Appl Pharmacol. 2014;279(3):380–90.
62. Loiola RA, Dos Anjos FM, Shimada AL, Cruz WS, Drewes CC, Rodrigues SF, et al. Longterm in vivo polychlorinated biphenyl 126 exposure induces oxidative stress and alters proteomic profile on islets of Langerhans. Sci Rep. 2016;6:27882.
63. Aoki Y. Polychlorinated biphenyls, polychloronated dibenzo-p-dioxins, and polychlorinated
dibenzofurans as endocrine disrupters—what we have learned from Yusho disease. Environ
Res. 2001;86(1):2–11.
64. Barsotti D, Allen J. Effects Of polychlorinated biphenyls on reproduction in primate.
Bethesda: Federation of American Societies for Experimental Biology; 1975. p. 20814–3998.
65. Kamarianos A, Karamanlis X, Goulas P, Theodosiadou E, Smokovitis A. The presence of
environmental pollutants in the follicular fluid of farm animals (cattle, sheep, goats, and
pigs). Reprod Toxicol. 2003;17(2):185–90.
66. Bergman A. Pathological changes in seals in Swedish waters: the relation to environmental
pollution. Doctoral thesis; 2007.
67. Bryce F, Hayward S, Stapley R, Arnold D. Consequences of Aroclor® 1254 ingestion on the menstrual cycle of rhesus (Macaca mulatta) monkeys. Food Chem Toxicol.
2000;38(11):1053–64.
68. Mukerjee D, Ruiz P. Halogenated biphenyls. Patty’s Toxicol. 2001;60:247–332.
69. Goldman D, Yawetz A. The interference of Aroclor 1254 with progesterone metabolism in
guinea pig adrenal and testes microsomes. J Biochem Toxicol. 1990;5(2):99–107.
70. BYRNE JJ, CARBONE JP, HANSON EA. Hypothyroidism and abnormalities in the kinetics
of thyroid hormone metabolism in rats treated chronically with polychlorinated biphenyl and
polybrominated biphenyl. Endocrinology. 1987;121(2):520–7.
71. Brouwer A, Morse DC, Lans MC, Gerlienke Schuur A, Murk AJ, Klasson-Wehler E, et al.
Interactions of persistent environmental organohalogens with the thyroid hormone system:
mechanisms and possible consequences for animal and human health. Toxicol Ind Health.
1998;14(1–2):59–84.
72. Hulbert A. Thyroid hormones and their effects: a new perspective. Biol Rev.
2000;75(4):519–631.
73. Bertazzi PA, Zocchetti C, Pesatori AC, Guercilena S, Sanarico M, Radice L. Ten-year mortality study of the population involved in the Seveso incident in 1976. Am J Epidemiol.
1989;129(6):1187–200.
74. Emmett EA, Maroni M, Jefferys J, Schmith J, Levin BK, Alvares A. Studies of transformer
repair workers exposed to PCBs: II. Results of clinical laboratory investigations. Am J Ind
Med. 1988;14(1):47–62.
W. Hassan et al.
56. Kurita H, Yoshioka W, Nishimura N, Kubota N, Kadowaki T, Tohyama C. Aryl hydrocarbon
receptor-mediated effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on glucose-stimulated
insulin secretion in mice. J Appl Toxicol. 2009;29(8):689–94.
57. Novelli M, Piaggi S, De Tata V. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin-induced impairment of glucose-stimulated insulin secretion in isolated rat pancreatic islets. Toxicol Lett.
2005;156(2):307–14.
58. Wassermann D, Wassermann M, Lemesch C. Ultrastructure of beta-cells of the endocrine pancreas in rats receiving polychlorinated biphenyls. Environ Physiol Biochem.
1975;5(5):322–40.
59. Fischer LJ, Zhou H-R, Wagner MA. Polychlorinated biphenyls release insulin from RINm5F
cells. Life Sci. 1996;59(24):2041–9.
60. Kim Y-H, Shim Y-J, Shin Y-J, Sul D, Lee E, Min B-H. 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
(TCDD) induces calcium influx through T-type calcium channel and enhances lysosomal
exocytosis and insulin secretion in INS-1 cells. Int J Toxicol. 2009;28(3):151–61.
61. Wahlang B, Song M, Beier JI, Falkner KC, Al-Eryani L, Clair HB, et al. Evaluation of
Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty
liver disease. Toxicol Appl Pharmacol. 2014;279(3):380–90.
62. Loiola RA, Dos Anjos FM, Shimada AL, Cruz WS, Drewes CC, Rodrigues SF, et al. Longterm in vivo polychlorinated biphenyl 126 exposure induces oxidative stress and alters proteomic profile on islets of Langerhans. Sci Rep. 2016;6:27882.
63. Aoki Y. Polychlorinated biphenyls, polychloronated dibenzo-p-dioxins, and polychlorinated
dibenzofurans as endocrine disrupters—what we have learned from Yusho disease. Environ
Res. 2001;86(1):2–11.
64. Barsotti D, Allen J. Effects Of polychlorinated biphenyls on reproduction in primate.
Bethesda: Federation of American Societies for Experimental Biology; 1975. p. 20814–3998.
65. Kamarianos A, Karamanlis X, Goulas P, Theodosiadou E, Smokovitis A. The presence of
environmental pollutants in the follicular fluid of farm animals (cattle, sheep, goats, and
pigs). Reprod Toxicol. 2003;17(2):185–90.
66. Bergman A. Pathological changes in seals in Swedish waters: the relation to environmental
pollution. Doctoral thesis; 2007.
67. Bryce F, Hayward S, Stapley R, Arnold D. Consequences of Aroclor® 1254 ingestion on the menstrual cycle of rhesus (Macaca mulatta) monkeys. Food Chem Toxicol.
2000;38(11):1053–64.
68. Mukerjee D, Ruiz P. Halogenated biphenyls. Patty’s Toxicol. 2001;60:247–332.
69. Goldman D, Yawetz A. The interference of Aroclor 1254 with progesterone metabolism in
guinea pig adrenal and testes microsomes. J Biochem Toxicol. 1990;5(2):99–107.
70. BYRNE JJ, CARBONE JP, HANSON EA. Hypothyroidism and abnormalities in the kinetics
of thyroid hormone metabolism in rats treated chronically with polychlorinated biphenyl and
polybrominated biphenyl. Endocrinology. 1987;121(2):520–7.
71. Brouwer A, Morse DC, Lans MC, Gerlienke Schuur A, Murk AJ, Klasson-Wehler E, et al.
Interactions of persistent environmental organohalogens with the thyroid hormone system:
mechanisms and possible consequences for animal and human health. Toxicol Ind Health.
1998;14(1–2):59–84.
72. Hulbert A. Thyroid hormones and their effects: a new perspective. Biol Rev.
2000;75(4):519–631.
73. Bertazzi PA, Zocchetti C, Pesatori AC, Guercilena S, Sanarico M, Radice L. Ten-year mortality study of the population involved in the Seveso incident in 1976. Am J Epidemiol.
1989;129(6):1187–200.
74. Emmett EA, Maroni M, Jefferys J, Schmith J, Levin BK, Alvares A. Studies of transformer
repair workers exposed to PCBs: II. Results of clinical laboratory investigations. Am J Ind
Med. 1988;14(1):47–62.
W. Hassan et al.