173
75. Huffman MD, Lloyd-Jones DM, Ning H, Labarthe DR, Guzman Castillo M, O’Flaherty M,
et al. Quantifying options for reducing coronary heart disease mortality by 2020. Circulation.
2013;127(25):2477–84.
76. Martin SS, Blaha MJ, Blankstein R, Agatston A, Rivera JJ, Virani SS, et al. Dyslipidemia,
coronary artery calcium, and incident atherosclerotic cardiovascular disease: implications for
statin therapy from the multi-ethnic study of atherosclerosis. Circulation. 2014;129(1):77–86.
77. Riche DM, McClendon KS. Role of statins for the primary prevention of cardiovascular disease in patients with type 2 diabetes mellitus. Am J Health Syst Pharm. 2007;64(15):1603–10.
78. Carloni S, Girelli S, Buonocore G, Longini M, Balduini W. Simvastatin acutely reduces
ischemic brain damage in the immature rat via Akt and CREB activation. Exp Neurol.
2009;220(1):82–9.
79. Stancu C, Sima A. Statins: mechanism of action and effects. J Cell Mol Med. 2001;5(4):378–87.
80. Bell FP, Iverson F, Arnold D, Vidmar TJ. Long-term effects of Aroclor 1254 (PCBs) on
plasma lipid and carnitine concentrations in rhesus monkey. Toxicology. 1994;89(2):139–53.
81. Hitomi Y, Yoshida A. Effect of methionine and threonine on the hypercholesterolemia
induced by polychlorinated biphenyls in rats fed a nonprotein diet. J Nutr Sci Vitaminol.
1989;35(6):589–96.
82. Nagaoka S, Kato M, Aoyama Y, Yoshida A. Comparative studies on the hypercholesterolaemia induced by excess dietary tyrosine or polychlorinated biphenyls in rats. Br J Nutr.
1986;56(2):509–17.
83. Arsenescu V, Arsenescu RI, King V, Swanson H, Cassis LA. Polychlorinated biphenyl-77
induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and
atherosclerosis. Environ Health Perspect. 2008;116(6):761–8.
84. Goncharov A, Pavuk M, Foushee HR, Carpenter DO. Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticides. Environ Health Perspect.
2010;119(3):319–25.
85. Lee D-H, Lee I-K, Song K, Steffes M, Toscano W, Baker BA, et al. A strong doseresponse relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999–2002. Diabetes Care.
2006;29(7):1638–44.
86. Baker NA, Karounos M, English V, Fang J, Wei Y, Stromberg A, et al. Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice. Environ Health Perspect.
2012;121(1):105–10.
87. Chase KH, Wong O, Thomas D, Berney B, Simon RK. Clinical and metabolic abnormalities
associated with occupational exposure to polychlorinated biphenyls (PCBs). J Occup Med.
1982;24(2):109–14.
88. Smith A, Schloemer J, Lowry L, Smallwood A, Ligo R, Tanaka S, et al. Metabolic and health
consequences of occupational exposure to polychlorinated biphenyls. Occup Environ Med.
1982;39(4):361–9.
89. Uemura H, Arisawa K, Hiyoshi M, Kitayama A, Takami H, Sawachika F, et al. Prevalence
of metabolic syndrome associated with body burden levels of dioxin and related compounds
among Japan’s general population. Environ Health Perspect. 2008;117(4):568–73.
90. Tokunaga S, Kataoka K. A longitudinal analysis on the association of serum lipids and
lipoproteins concentrations with blood polychlorinated biphenyls level in chronic "Yusho"
patients. Fukuoka Acta Medica. 2003;94(5):32–9.
91. Stehr-Green PA, Welty E, Steele G, Steinberg K. Evaluation of potential health effects associated with serum polychlorinated biphenyl levels. Environ Health Perspect. 1986;70:255–9.
92. Hardesty J. Epidermal growth factor receptor (EGFR) inhibition by polychlorinated biphenyls
contributes to non-alcoholic fatty liver disease (NAFLD). Doctoral dissertation, University of
Louisville; 2018.
11 Role of Polychlorinated Biphenyls as EDCs in Metabolic Disorders
75. Huffman MD, Lloyd-Jones DM, Ning H, Labarthe DR, Guzman Castillo M, O’Flaherty M,
et al. Quantifying options for reducing coronary heart disease mortality by 2020. Circulation.
2013;127(25):2477–84.
76. Martin SS, Blaha MJ, Blankstein R, Agatston A, Rivera JJ, Virani SS, et al. Dyslipidemia,
coronary artery calcium, and incident atherosclerotic cardiovascular disease: implications for
statin therapy from the multi-ethnic study of atherosclerosis. Circulation. 2014;129(1):77–86.
77. Riche DM, McClendon KS. Role of statins for the primary prevention of cardiovascular disease in patients with type 2 diabetes mellitus. Am J Health Syst Pharm. 2007;64(15):1603–10.
78. Carloni S, Girelli S, Buonocore G, Longini M, Balduini W. Simvastatin acutely reduces
ischemic brain damage in the immature rat via Akt and CREB activation. Exp Neurol.
2009;220(1):82–9.
79. Stancu C, Sima A. Statins: mechanism of action and effects. J Cell Mol Med. 2001;5(4):378–87.
80. Bell FP, Iverson F, Arnold D, Vidmar TJ. Long-term effects of Aroclor 1254 (PCBs) on
plasma lipid and carnitine concentrations in rhesus monkey. Toxicology. 1994;89(2):139–53.
81. Hitomi Y, Yoshida A. Effect of methionine and threonine on the hypercholesterolemia
induced by polychlorinated biphenyls in rats fed a nonprotein diet. J Nutr Sci Vitaminol.
1989;35(6):589–96.
82. Nagaoka S, Kato M, Aoyama Y, Yoshida A. Comparative studies on the hypercholesterolaemia induced by excess dietary tyrosine or polychlorinated biphenyls in rats. Br J Nutr.
1986;56(2):509–17.
83. Arsenescu V, Arsenescu RI, King V, Swanson H, Cassis LA. Polychlorinated biphenyl-77
induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and
atherosclerosis. Environ Health Perspect. 2008;116(6):761–8.
84. Goncharov A, Pavuk M, Foushee HR, Carpenter DO. Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticides. Environ Health Perspect.
2010;119(3):319–25.
85. Lee D-H, Lee I-K, Song K, Steffes M, Toscano W, Baker BA, et al. A strong doseresponse relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999–2002. Diabetes Care.
2006;29(7):1638–44.
86. Baker NA, Karounos M, English V, Fang J, Wei Y, Stromberg A, et al. Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice. Environ Health Perspect.
2012;121(1):105–10.
87. Chase KH, Wong O, Thomas D, Berney B, Simon RK. Clinical and metabolic abnormalities
associated with occupational exposure to polychlorinated biphenyls (PCBs). J Occup Med.
1982;24(2):109–14.
88. Smith A, Schloemer J, Lowry L, Smallwood A, Ligo R, Tanaka S, et al. Metabolic and health
consequences of occupational exposure to polychlorinated biphenyls. Occup Environ Med.
1982;39(4):361–9.
89. Uemura H, Arisawa K, Hiyoshi M, Kitayama A, Takami H, Sawachika F, et al. Prevalence
of metabolic syndrome associated with body burden levels of dioxin and related compounds
among Japan’s general population. Environ Health Perspect. 2008;117(4):568–73.
90. Tokunaga S, Kataoka K. A longitudinal analysis on the association of serum lipids and
lipoproteins concentrations with blood polychlorinated biphenyls level in chronic "Yusho"
patients. Fukuoka Acta Medica. 2003;94(5):32–9.
91. Stehr-Green PA, Welty E, Steele G, Steinberg K. Evaluation of potential health effects associated with serum polychlorinated biphenyl levels. Environ Health Perspect. 1986;70:255–9.
92. Hardesty J. Epidermal growth factor receptor (EGFR) inhibition by polychlorinated biphenyls
contributes to non-alcoholic fatty liver disease (NAFLD). Doctoral dissertation, University of
Louisville; 2018.
11 Role of Polychlorinated Biphenyls as EDCs in Metabolic Disorders