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Preface
Metabolic disorders (MDs) are promptly aggregating in the increasing population
globally. This is greatly affecting the social and financial status of individuals particularly of developing and/or underdeveloped countries. Unfortunately, specifically
these countries are also victims of environmental contaminants and habitual impurities that can be considered as the foremost keystones not only for initiating the
occurrence but also for flourishing the progress of MDs. These contaminants include
a major contribution of endocrine-disrupting chemicals (EDCs). According to the
World Health Organization (WHO), these EDCs are “mostly man-made, found in
various materials such as pesticides, metals, additives or contaminants in food, and
personal care products” and that “Human exposure to EDCs occurs via ingestion of
food, dust, and water, via inhalation of gases and particles in the air, and through the
skin.” This accentuates the urge to better comprehend the principal disease mechanisms, which will not only help in eradicating these underpinning causative factors
but may also propose targeted therapy for the MDs caused by EDCs.
This book entitled “Endocrine-Disrupting Chemicals-induced Metabolic
Disorders and Treatment Strategies” is envisioned to first provide an introduction to
the endocrine system and MDs followed by a profound discussion on the role of
various EDCs and/or sources of EDCs in causing the induction, prevalence, and
even progression of MDs. Lastly, in the third part of this book, we have deliberated
the potential account of prevention and therapeutic intervention by elaborating the
treatment strategies of EDCs-induced metabolic disorders.
We considered writing this book as till now, there is no such comprehensive text
available in a compiled book format that can actually provide the broad notion of
EDCs-induced MDs under one roof in a co-jointed manner. Nevertheless, existing
books on the said topic seem to be presented in a fragmented way limited to the
introduction of either endocrine or MDs. They deliver more like a repetition of basic
endocrinology rather than a rational staircase compiling the physiology of the endocrine system and related metabolic disorders which comprehensively provide endocrine gland’s physiology; moreover, we have also discussed in detail all the
associated endocrine metabolic disorders, i.e. hyperthyroidism, hypothyroidism,
iodine deficiency, hypoparathyroidism, adrenal insufficiency, Cushing’s syndrome,
Preface
Metabolic disorders (MDs) are promptly aggregating in the increasing population
globally. This is greatly affecting the social and financial status of individuals particularly of developing and/or underdeveloped countries. Unfortunately, specifically
these countries are also victims of environmental contaminants and habitual impurities that can be considered as the foremost keystones not only for initiating the
occurrence but also for flourishing the progress of MDs. These contaminants include
a major contribution of endocrine-disrupting chemicals (EDCs). According to the
World Health Organization (WHO), these EDCs are “mostly man-made, found in
various materials such as pesticides, metals, additives or contaminants in food, and
personal care products” and that “Human exposure to EDCs occurs via ingestion of
food, dust, and water, via inhalation of gases and particles in the air, and through the
skin.” This accentuates the urge to better comprehend the principal disease mechanisms, which will not only help in eradicating these underpinning causative factors
but may also propose targeted therapy for the MDs caused by EDCs.
This book entitled “Endocrine-Disrupting Chemicals-induced Metabolic
Disorders and Treatment Strategies” is envisioned to first provide an introduction to
the endocrine system and MDs followed by a profound discussion on the role of
various EDCs and/or sources of EDCs in causing the induction, prevalence, and
even progression of MDs. Lastly, in the third part of this book, we have deliberated
the potential account of prevention and therapeutic intervention by elaborating the
treatment strategies of EDCs-induced metabolic disorders.
We considered writing this book as till now, there is no such comprehensive text
available in a compiled book format that can actually provide the broad notion of
EDCs-induced MDs under one roof in a co-jointed manner. Nevertheless, existing
books on the said topic seem to be presented in a fragmented way limited to the
introduction of either endocrine or MDs. They deliver more like a repetition of basic
endocrinology rather than a rational staircase compiling the physiology of the endocrine system and related metabolic disorders which comprehensively provide endocrine gland’s physiology; moreover, we have also discussed in detail all the
associated endocrine metabolic disorders, i.e. hyperthyroidism, hypothyroidism,
iodine deficiency, hypoparathyroidism, adrenal insufficiency, Cushing’s syndrome,