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Foreword
Ciarán Martin Fitzpatrick, PhD
Molecular Neuropharmacology
and Genetics Laboratory
Department of Drug Design and Pharmacology
Faculty of Health and Medical Sciences
University of Copenhagen
Copenhagen, Denmark
Endocrine Disrupting Chemicals-Induced Metabolic
Disorders
We live in a world surrounded by environmental pollutants and toxicants, including
endocrine-disrupting chemicals (EDCs) which pose a significant health risk to current and future generations of humans and animals alike. Some of these EDCs are
understudied or, even more frightening, undiscovered. Other chemicals currently
deemed safe may be dangerous, and their adverse outcomes are not yet measurable.
Therefore, high-quality research and publications are necessary to raise awareness
and guide scientists, policymakers, and the public.
This book introduces the normal and maladaptive processes of the endocrine system, glands, and associated disorders, including EDCs-induced metabolic ones. The
essential material detailed within is the preventive and intervention treatment strategies potential in combating these illnesses. The many authors of these different
chapters have contributed to highlighting the therapeutic impact of these bioactive
compounds, further adding to this work’s importance and educational value.
Enduring damaging effects of EDCs is something that will arouse interest in readers, herein debating hot topics from alterations in the gut microbiota to enhanced
antibiotic resistance. Discussion to positive lifestyle changes in metabolic disorders are given relating to intermittent fasting and some bioactive compounds present in food, is of interest to the layperson. This may reveal candidate targets for
pharmaceutical drug development, as responsivity is needed to fight our widening
obesity pandemic.
The dual basic/clinical nature of this book allows researchers from both ends of the
spectrum to read and learn. Providing knowledge and understanding based on studies thus far allows this book to act as a companion resource for both undergraduate
and post-graduate students in the Health Sciences.
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