Moorthi C, Krishnan K, Manavalan R, Kathiresan K (2012) Preparation and characterization of
curcumin-piperine dual drug loaded nanoparticles. Asian Pac J Trop Biomed 2(11):841–848
Mujumdar AM, Dhuley JN, Deshmukh VK, Raman PH, Thorat SL, Naik SR (1990) Effect of
piperine on pentobarbitone induced hypnosis in rats. Indian J Exp Biol 28(5):486–487
Neumann M, Fries H, Scheicher C, Keikavoussi P, Kolb-Mäurer A, Bröcker E, Serfling E,
Kämpgen E (2000) Differential expression of Rel/NF-kappaB and octamer factors is a hallmark
of the generation and maturation of dendritic cells. Blood 95(1):277–285
Nimse SB, Pal D (2015) Free radicals, natural antioxidants and their reaction mechanisms. RSC
Adv 5(35):27986–28006
Oberley LW (1988) Free radicals and diabetes. Free Radic Biol Med 5(2):113–124
Ochi H, Morita I, Murota S (1992) Mechanism for endothelial cell injury induced by
15-hydroperoxyeicosatetraenoic acid, an arachidonate lipoxygenase product. Biochim
Biophys Acta 1136(3):247–252
Ouadid-Ahidouch H, Ahidouch A (2008) K+ channel expression in human breast cancer cells:
involvement in cell cycle regulation and carcinogenesis. J Membr Biol 221(1):1–6
Ouadid-Ahidouch H, Ahidouch A (2013) K(+) channels and cell cycle progression in tumor cells.
Front Physiol 4:220
Pal D, Nandi M (2005) CNS activities of Celsia coromandeliane Vahl in mice. Acta Polon Pharm
Drug Res 62(5):355–361
Pal D, Kumar M, Chakrabarty P, Kumar S (2008) Evaluation of the antioxidant activity of aerial
parts of Cynodon dacvtylon. Asian J Chem 20(3):2479–2481
Pal D, Sannigrahi S, Mazumder UK (2009) Analgesic and anticonvulsant effects of isolated
saponin from the leaves of Clerodendrum infortunatum Linn. in mice. Indian J Exp Biol
47:743–747
Pal D (2013) Comparative analysis of in vitro antioxidant activity of two selected plants with a
reference to antidiabetic profile. Asian J Chem 25(4):2165–2169
Pal D, Mazumder UK (2014) Isolation of compound and studies on CNS depressant activities of
Mikania scandens Wild with special emphasis to brain biogenic amines in mice. Indian J Exp
Biol 52:1186–1194
Paarakh PM, Sreeram DC, D SS, Ganapathy SP, (2015) In vitro cytotoxic and in silico activity of
piperine isolated from Piper nigrum fruits Linn. Silico Pharmacol 3(1):9
Patel SG, Patel JK, Patel K (2012) Comparison and quantification of marker compound of triphala
guggulu by using HPTLC method. Am J Pharm Tech Res 2(4):999–1013
Pei YQ (1983) A Review of Pharmacology and Clinical Use of Piperine and Its Derivatives.
Epilepsia 24(2):177–182
Pooja S, Agrawal RP, Nyati P, Savita V, Phadnis P (2007) Analgesic activity of Piper nigrum
extract per se and its interaction with diclofenac sodium and pentazocine in albino mice. Int J
Pharmacol 5(1):30
Pradeep CR, Kuttan G (2003) Effect of piperine on the inhibition of nitric oxide (NO) and
TNF-alpha production. Immunopharm Immun 25(3):337–346
Pradeep CR, Kuttan G (2004) Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB),
c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F–10 melanoma
cells. Int Immunopharm 4(14):1795–1803
Prevarskaya N, Skryma R, Bidaux G, Flourakis M, Shuba Y (2007) Ion channels in death and
differentiation of prostate cancer cells. Cell Death Differ 14(7):1295–1304
Quéméneur L, Gerland LM, Flacher M, Ffrench M, Revillard JP, Genestier L (2003) Differential
control of cell cycle, proliferation, and survival of primary T lymphocytes by purine and
pyrimidine nucleotides. J Immunol 170(10):4986–4995
Rabb H, Griffin MD, McKay DB, Swaminathan S, Pickkers P, Rosner MH, Kellum JA, Ronco C
(2016) Inflammation in AKI: current understanding, key questions, and knowledge gaps. J Am
Soc Nephrol 27(2):371–379
Raman G, Gaikar VG (2002) Microwave-Assisted Extraction of Piperine from Piper nigrum.
Indus. Eng Chem Res 41:2521–2528
788
N. Sachan et al.
curcumin-piperine dual drug loaded nanoparticles. Asian Pac J Trop Biomed 2(11):841–848
Mujumdar AM, Dhuley JN, Deshmukh VK, Raman PH, Thorat SL, Naik SR (1990) Effect of
piperine on pentobarbitone induced hypnosis in rats. Indian J Exp Biol 28(5):486–487
Neumann M, Fries H, Scheicher C, Keikavoussi P, Kolb-Mäurer A, Bröcker E, Serfling E,
Kämpgen E (2000) Differential expression of Rel/NF-kappaB and octamer factors is a hallmark
of the generation and maturation of dendritic cells. Blood 95(1):277–285
Nimse SB, Pal D (2015) Free radicals, natural antioxidants and their reaction mechanisms. RSC
Adv 5(35):27986–28006
Oberley LW (1988) Free radicals and diabetes. Free Radic Biol Med 5(2):113–124
Ochi H, Morita I, Murota S (1992) Mechanism for endothelial cell injury induced by
15-hydroperoxyeicosatetraenoic acid, an arachidonate lipoxygenase product. Biochim
Biophys Acta 1136(3):247–252
Ouadid-Ahidouch H, Ahidouch A (2008) K+ channel expression in human breast cancer cells:
involvement in cell cycle regulation and carcinogenesis. J Membr Biol 221(1):1–6
Ouadid-Ahidouch H, Ahidouch A (2013) K(+) channels and cell cycle progression in tumor cells.
Front Physiol 4:220
Pal D, Nandi M (2005) CNS activities of Celsia coromandeliane Vahl in mice. Acta Polon Pharm
Drug Res 62(5):355–361
Pal D, Kumar M, Chakrabarty P, Kumar S (2008) Evaluation of the antioxidant activity of aerial
parts of Cynodon dacvtylon. Asian J Chem 20(3):2479–2481
Pal D, Sannigrahi S, Mazumder UK (2009) Analgesic and anticonvulsant effects of isolated
saponin from the leaves of Clerodendrum infortunatum Linn. in mice. Indian J Exp Biol
47:743–747
Pal D (2013) Comparative analysis of in vitro antioxidant activity of two selected plants with a
reference to antidiabetic profile. Asian J Chem 25(4):2165–2169
Pal D, Mazumder UK (2014) Isolation of compound and studies on CNS depressant activities of
Mikania scandens Wild with special emphasis to brain biogenic amines in mice. Indian J Exp
Biol 52:1186–1194
Paarakh PM, Sreeram DC, D SS, Ganapathy SP, (2015) In vitro cytotoxic and in silico activity of
piperine isolated from Piper nigrum fruits Linn. Silico Pharmacol 3(1):9
Patel SG, Patel JK, Patel K (2012) Comparison and quantification of marker compound of triphala
guggulu by using HPTLC method. Am J Pharm Tech Res 2(4):999–1013
Pei YQ (1983) A Review of Pharmacology and Clinical Use of Piperine and Its Derivatives.
Epilepsia 24(2):177–182
Pooja S, Agrawal RP, Nyati P, Savita V, Phadnis P (2007) Analgesic activity of Piper nigrum
extract per se and its interaction with diclofenac sodium and pentazocine in albino mice. Int J
Pharmacol 5(1):30
Pradeep CR, Kuttan G (2003) Effect of piperine on the inhibition of nitric oxide (NO) and
TNF-alpha production. Immunopharm Immun 25(3):337–346
Pradeep CR, Kuttan G (2004) Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB),
c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F–10 melanoma
cells. Int Immunopharm 4(14):1795–1803
Prevarskaya N, Skryma R, Bidaux G, Flourakis M, Shuba Y (2007) Ion channels in death and
differentiation of prostate cancer cells. Cell Death Differ 14(7):1295–1304
Quéméneur L, Gerland LM, Flacher M, Ffrench M, Revillard JP, Genestier L (2003) Differential
control of cell cycle, proliferation, and survival of primary T lymphocytes by purine and
pyrimidine nucleotides. J Immunol 170(10):4986–4995
Rabb H, Griffin MD, McKay DB, Swaminathan S, Pickkers P, Rosner MH, Kellum JA, Ronco C
(2016) Inflammation in AKI: current understanding, key questions, and knowledge gaps. J Am
Soc Nephrol 27(2):371–379
Raman G, Gaikar VG (2002) Microwave-Assisted Extraction of Piperine from Piper nigrum.
Indus. Eng Chem Res 41:2521–2528
788
N. Sachan et al.