Gibson HE, Edwards JG, Page RS, Van Hook MJ, Kauer JA (2008) TRPV1 channels mediate
long-term depression at synapses on hippocampal interneurons. Neuron 57(5):746–759
Goligorsky MS, Brodsky SV, Noiri E (2002) Nitric oxide in acute renal failure: NOS versus NOS.
Kidney Int 61(3):855–861
Guirgis HM (2015) The value of anticancer drugs in metastatic castrate-resistant prostate cancer:
economic tools for the community oncologist. J Commun Support Oncol 13(10):362–366
Gunasekar PG, Kanthasamy AG, Borowitz JL, Isom GE (1995) NMDA receptor activation
produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell
death. J Neurochem 65(5):2016–2021
Gupta M, Mazumder UK, Pal D, Bhattacharya S and Chakrabarty S (2003) Studies on brain
biogenic amines in methanolic extract of Cuscuta reflexa Roxb stem and Corchorus olitorius
Linn. seed treated mice, Acta-Polon Pharm Drug Res 60(3):207–210
Gupta SK, Velpandian T, Sengupta S, Mathur P, Sapra P (1998) Influence of piperine on
nimesulide induced antinociception. Phytother Res 12(4):266–269
Gupta V, Jain UK (2011a) Estimation of piperine by UV-spectrophotometric method in herbal
formulation, Pippli Churna. Int J Res Pharmaceut Biomed Sci 2(2):550–553
Gupta V, Jain UK (2011b) Quantitative analysis of piperine in ayurvedic formulation by UV
Spectrophotometry. Int J Pharmaceut Sci Res 2(2):58–61
Gupta V, Jain UK (2011c) Status of piperine content in ayurvedic formulation: method
standardization by HPTLC. Res J Pharmaceut Biol Chem Sci 2(2):524–532
Hunt JV, Dean RT, Wolff SP (1988) Hydroxyl radical production and autoxidative glycosylation.
Glucose autoxidation as the cause of protein damage in the experimental glycation model of
diabetes mellitus and ageing. Biochem J 256(1): 205–212
Hwang YP, Yun HJ, Kim HG, Han EH, Choi JH, Chung YC, Jeong HG (2011) Suppression of
phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of
PKCa/ERK1/2-dependent matrix metalloproteinase-9 expression. Toxicol Lett 203(1):9–19
Janakiraman K, Manavalan R (2008) Studies on effect of piperine on oral bioavailability of
ampicillin and norfloxacin. Afr J Tradit Complement Altern Med 5(3):257–262
Joe B, Lokesh BR (1994) Role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the
generation of reactive oxygen species in rat peritoneal macrophages. Biochim Biophys Acta
1224(2):255–263
Johri RK, Thusu N, Khajuria A, Zutshi U (1992) Piperine-mediated changes in the permeability of
rat intestinal epithelial cells. The status of gamma-glutamyl transpeptidase activity, uptake of
amino acids and lipid peroxidation. Biochem Pharmacol 43(7): 1401–1407
Kachel DL, Moyer TP, Martin WJ 2nd (1990) Amiodarone-induced injury of human pulmonary
artery endothelial cells: protection by alpha-tocopherol. J Pharmacol Exp Ther 254(3):1107–
1112
Karan RS, Bhargava VK, Garg SK (1988) Effect of trikatu (PIPERINE) on the pharmacokinetic
profile of isoniazid in rabbits. Ind J Pharmacol 30(4):254–256
Karan S, Mishra S, Pal D (2012) Isolation of beta sitosterol and evaluation of antidiabetic activity
of Aristolochia indica in alloxan induced diabetic mice with a special reference to in vitro
antioxidant activity. J Med Plant Res 6(7):1219–1223
Kasibhatta R, Naidu MU (2007) Influence of piperine on the pharmacokinetics of nevirapine under
fasting conditions: a randomised, crossover, placebo-controlled study. Drugs R D 8(6):383–
391
Kauer JA, Gibson HE (2009) Hot flash: TRPV channels in the brain. Trends Neurosci 32(4):215–
224
Kehrer JP, Klotz LO (2015) Free radicals and related reactive species as mediators of tissue injury
and disease: implications for Health. Crit Rev Toxicol 45(9):765–798
Kerr BM, Thummel KE, Wurden CJ, Klein SM, Kroetz DL, Gonzalez FJ, Levy RH (1994) Human
liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation.
Biochem Pharmacol 47(11):1969–1979
Khan WN, Wright JA, Kleiman E, Boucher JC, Castro I, Clark ES (2013) B-lymphocyte tolerance
and effector function in immunity and autoimmunity. Immunol Res 57(1–3):335–353
786
N. Sachan et al.
long-term depression at synapses on hippocampal interneurons. Neuron 57(5):746–759
Goligorsky MS, Brodsky SV, Noiri E (2002) Nitric oxide in acute renal failure: NOS versus NOS.
Kidney Int 61(3):855–861
Guirgis HM (2015) The value of anticancer drugs in metastatic castrate-resistant prostate cancer:
economic tools for the community oncologist. J Commun Support Oncol 13(10):362–366
Gunasekar PG, Kanthasamy AG, Borowitz JL, Isom GE (1995) NMDA receptor activation
produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell
death. J Neurochem 65(5):2016–2021
Gupta M, Mazumder UK, Pal D, Bhattacharya S and Chakrabarty S (2003) Studies on brain
biogenic amines in methanolic extract of Cuscuta reflexa Roxb stem and Corchorus olitorius
Linn. seed treated mice, Acta-Polon Pharm Drug Res 60(3):207–210
Gupta SK, Velpandian T, Sengupta S, Mathur P, Sapra P (1998) Influence of piperine on
nimesulide induced antinociception. Phytother Res 12(4):266–269
Gupta V, Jain UK (2011a) Estimation of piperine by UV-spectrophotometric method in herbal
formulation, Pippli Churna. Int J Res Pharmaceut Biomed Sci 2(2):550–553
Gupta V, Jain UK (2011b) Quantitative analysis of piperine in ayurvedic formulation by UV
Spectrophotometry. Int J Pharmaceut Sci Res 2(2):58–61
Gupta V, Jain UK (2011c) Status of piperine content in ayurvedic formulation: method
standardization by HPTLC. Res J Pharmaceut Biol Chem Sci 2(2):524–532
Hunt JV, Dean RT, Wolff SP (1988) Hydroxyl radical production and autoxidative glycosylation.
Glucose autoxidation as the cause of protein damage in the experimental glycation model of
diabetes mellitus and ageing. Biochem J 256(1): 205–212
Hwang YP, Yun HJ, Kim HG, Han EH, Choi JH, Chung YC, Jeong HG (2011) Suppression of
phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of
PKCa/ERK1/2-dependent matrix metalloproteinase-9 expression. Toxicol Lett 203(1):9–19
Janakiraman K, Manavalan R (2008) Studies on effect of piperine on oral bioavailability of
ampicillin and norfloxacin. Afr J Tradit Complement Altern Med 5(3):257–262
Joe B, Lokesh BR (1994) Role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the
generation of reactive oxygen species in rat peritoneal macrophages. Biochim Biophys Acta
1224(2):255–263
Johri RK, Thusu N, Khajuria A, Zutshi U (1992) Piperine-mediated changes in the permeability of
rat intestinal epithelial cells. The status of gamma-glutamyl transpeptidase activity, uptake of
amino acids and lipid peroxidation. Biochem Pharmacol 43(7): 1401–1407
Kachel DL, Moyer TP, Martin WJ 2nd (1990) Amiodarone-induced injury of human pulmonary
artery endothelial cells: protection by alpha-tocopherol. J Pharmacol Exp Ther 254(3):1107–
1112
Karan RS, Bhargava VK, Garg SK (1988) Effect of trikatu (PIPERINE) on the pharmacokinetic
profile of isoniazid in rabbits. Ind J Pharmacol 30(4):254–256
Karan S, Mishra S, Pal D (2012) Isolation of beta sitosterol and evaluation of antidiabetic activity
of Aristolochia indica in alloxan induced diabetic mice with a special reference to in vitro
antioxidant activity. J Med Plant Res 6(7):1219–1223
Kasibhatta R, Naidu MU (2007) Influence of piperine on the pharmacokinetics of nevirapine under
fasting conditions: a randomised, crossover, placebo-controlled study. Drugs R D 8(6):383–
391
Kauer JA, Gibson HE (2009) Hot flash: TRPV channels in the brain. Trends Neurosci 32(4):215–
224
Kehrer JP, Klotz LO (2015) Free radicals and related reactive species as mediators of tissue injury
and disease: implications for Health. Crit Rev Toxicol 45(9):765–798
Kerr BM, Thummel KE, Wurden CJ, Klein SM, Kroetz DL, Gonzalez FJ, Levy RH (1994) Human
liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation.
Biochem Pharmacol 47(11):1969–1979
Khan WN, Wright JA, Kleiman E, Boucher JC, Castro I, Clark ES (2013) B-lymphocyte tolerance
and effector function in immunity and autoimmunity. Immunol Res 57(1–3):335–353
786
N. Sachan et al.