References
Abdul M, Hoosein N (2002) Expression and activity of potassium ion channels in human prostate
cancer. Cancer Lett 186(1):99–105
Abuelo JG (2007) Normotensive ischemic acute renal failure. N Engl J Med 357(8):797–805
Ashour EA, Majumdar S, Alsheteli A, Alshehri S, Alsulays B, Feng X, Gryczke A, Kolter K,
Langley N, Repka MA (2016) Hot melt extrusion as an approach to improve solubility,
permeability and oral absorption of a psychoactive natural product, piperine. J Pharm
Pharmacol 68(8):989–998
Atal CK, Dubey RK, Singh J (1985) Biochemical basis of enhanced drug bioavailability by
piperine: evidence that piperine is a potent inhibitor of drug metabolism. J Pharmacol Exp Ther
232(1):258–262
Bae GS, Kim JJ, Park KC, Koo BS, Jo IJ, Choi SB, Lee CH, Jung WS, Cho JH, Hong SH,
Song HJ, Shin YK, Park SJ (2012) Piperine inhibits lipopolysaccharide-induced maturation of
bone-marrow-derived dendritic cells through inhibition of ERK and JNK activation. Phytother
Res 26(12):1893–1897
Balakrishnan V, Varma S, Chatterji D (2001) Piperine augments transcription inhibitory activity of
rifampicin by severalfold in Mycobacterium smegmatis. Curr Sci 80(10):1302–1305
Bang JS, Oh DH, Choi HM, Sur BJ, Lim SJ, Kim JY, Yang HI, Yoo MC, Hahm DH, Kim KS
(2009) Anti-inflammatory and antiarthritic effects of piperine in human interleukin
1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models. Arthritis Res Ther
11(2):R49
Bano G, Amla V, Raina RK, Zutshi U, Chopra CL (1987) The effect of piperine on
pharmacokinetics of phenytoin in healthy volunteers. Planta Med 53(6):568–569
Bari SB, Adhikari S, Surana SJ (2012) Tyrosine kinase receptor inhibitors: A new target for
anticancer drug development. J Pharma Sci Tech 1(2):36–45
Basile DP, Yoder MC (2014) Renal endothelial dysfunction in acute kidney ischemia reperfusion
injury. Cardiovasc Hematol Disord Drug Targets 14(1):3–14
Bialer M, Levy RH, Perucca E (1998) Does carbamazepine have a narrow therapeutic plasma
concentration range? Ther Drug Monit 20(1):56–59
Bolaños JP, Heales SJ, Land JM, Clark JB (1995) Effect of peroxynitrite on the mitochondrial
respiratory chain: differential susceptibility of neurones and astrocytes in primary culture.
J Neurochem 64(5):1965–1972
Browning RA, Smith JK, Brandon MT (1983) Comparison of regional brain 5-HT and 5-HIAA
content in flexor and extensor rats. Pharmacol Biochem Behav 18(4):525–528
Bukhari IA, Pivac N, Alhumayyd MS, Mahesar AL, Gilani AH (2013) The analgesic and
anticonvulsant effects of piperine in mice. J Physiol Pharmacol 64(6):789–794
Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA (2007) IL-2 receptor beta-dependent
STAT5 activation is required for the development of Foxp3+ regulatory T cells. J Immunol 178
(1):280–290
Chatterjee PK, Patel NS, Sivarajah A, Kvale EO, Dugo L, Cuzzocrea S, Brown PA, Stewart KN,
Mota-Filipe H, Britti D, Yaqoob MM, Thiemermann C (2003) GW274150, a potent and highly
selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Kidney Int
63(3):853–865
Chavarria D, Silva T, Magalhães e Silva D, Remião F, Borges F, (2016) Lessons from black
pepper: piperine and derivatives thereof. Expert Opin Ther Pat 26(2):245–264
Chávez AE, Chiu CQ, Castillo PE (2010) TRPV1 activation by endogenous anandamide triggers
postsynaptic long-term depression in dentate gyrus. Nat Neurosci 13(12):1511–1518
Chen CY, Li W, Qu KP, Chen CR (2013) Piperine exerts anti-seizure effects via the TRPV1
receptor in mice. Eur J Pharmacol 714(1–3):288–294
Chen GY, Nuñez G (2010) Sterile inflammation: sensing and reacting to damage. Nat Rev
Immunol 10(12):826–837
784
N. Sachan et al.
Abdul M, Hoosein N (2002) Expression and activity of potassium ion channels in human prostate
cancer. Cancer Lett 186(1):99–105
Abuelo JG (2007) Normotensive ischemic acute renal failure. N Engl J Med 357(8):797–805
Ashour EA, Majumdar S, Alsheteli A, Alshehri S, Alsulays B, Feng X, Gryczke A, Kolter K,
Langley N, Repka MA (2016) Hot melt extrusion as an approach to improve solubility,
permeability and oral absorption of a psychoactive natural product, piperine. J Pharm
Pharmacol 68(8):989–998
Atal CK, Dubey RK, Singh J (1985) Biochemical basis of enhanced drug bioavailability by
piperine: evidence that piperine is a potent inhibitor of drug metabolism. J Pharmacol Exp Ther
232(1):258–262
Bae GS, Kim JJ, Park KC, Koo BS, Jo IJ, Choi SB, Lee CH, Jung WS, Cho JH, Hong SH,
Song HJ, Shin YK, Park SJ (2012) Piperine inhibits lipopolysaccharide-induced maturation of
bone-marrow-derived dendritic cells through inhibition of ERK and JNK activation. Phytother
Res 26(12):1893–1897
Balakrishnan V, Varma S, Chatterji D (2001) Piperine augments transcription inhibitory activity of
rifampicin by severalfold in Mycobacterium smegmatis. Curr Sci 80(10):1302–1305
Bang JS, Oh DH, Choi HM, Sur BJ, Lim SJ, Kim JY, Yang HI, Yoo MC, Hahm DH, Kim KS
(2009) Anti-inflammatory and antiarthritic effects of piperine in human interleukin
1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models. Arthritis Res Ther
11(2):R49
Bano G, Amla V, Raina RK, Zutshi U, Chopra CL (1987) The effect of piperine on
pharmacokinetics of phenytoin in healthy volunteers. Planta Med 53(6):568–569
Bari SB, Adhikari S, Surana SJ (2012) Tyrosine kinase receptor inhibitors: A new target for
anticancer drug development. J Pharma Sci Tech 1(2):36–45
Basile DP, Yoder MC (2014) Renal endothelial dysfunction in acute kidney ischemia reperfusion
injury. Cardiovasc Hematol Disord Drug Targets 14(1):3–14
Bialer M, Levy RH, Perucca E (1998) Does carbamazepine have a narrow therapeutic plasma
concentration range? Ther Drug Monit 20(1):56–59
Bolaños JP, Heales SJ, Land JM, Clark JB (1995) Effect of peroxynitrite on the mitochondrial
respiratory chain: differential susceptibility of neurones and astrocytes in primary culture.
J Neurochem 64(5):1965–1972
Browning RA, Smith JK, Brandon MT (1983) Comparison of regional brain 5-HT and 5-HIAA
content in flexor and extensor rats. Pharmacol Biochem Behav 18(4):525–528
Bukhari IA, Pivac N, Alhumayyd MS, Mahesar AL, Gilani AH (2013) The analgesic and
anticonvulsant effects of piperine in mice. J Physiol Pharmacol 64(6):789–794
Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA (2007) IL-2 receptor beta-dependent
STAT5 activation is required for the development of Foxp3+ regulatory T cells. J Immunol 178
(1):280–290
Chatterjee PK, Patel NS, Sivarajah A, Kvale EO, Dugo L, Cuzzocrea S, Brown PA, Stewart KN,
Mota-Filipe H, Britti D, Yaqoob MM, Thiemermann C (2003) GW274150, a potent and highly
selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Kidney Int
63(3):853–865
Chavarria D, Silva T, Magalhães e Silva D, Remião F, Borges F, (2016) Lessons from black
pepper: piperine and derivatives thereof. Expert Opin Ther Pat 26(2):245–264
Chávez AE, Chiu CQ, Castillo PE (2010) TRPV1 activation by endogenous anandamide triggers
postsynaptic long-term depression in dentate gyrus. Nat Neurosci 13(12):1511–1518
Chen CY, Li W, Qu KP, Chen CR (2013) Piperine exerts anti-seizure effects via the TRPV1
receptor in mice. Eur J Pharmacol 714(1–3):288–294
Chen GY, Nuñez G (2010) Sterile inflammation: sensing and reacting to damage. Nat Rev
Immunol 10(12):826–837
784
N. Sachan et al.