Table 12.3
(continued)
Active
constituent
Nanocarrier
Disease/microbe(s)
Remark
References
Allicin
–
Trichophyton rubrum
Pure allicin extract was more efficient than garlic extract to
impede the h0yphae cell growth
Aala et al. (2014)
Allicin
–
Antibacterial and antifungal
activity
The various thiosulfonates analogous of allicin were tested.
The more volatile compounds exhibited substantial
antimicrobial properties
Leontiev et al.
(2018)
Ajoene
–
Antimycobacterial activity
When the ajoene was treated with macrophage. Ajoene
stimulated the JNK followed by the initiation of ROS
production and accumulation resulted in stimulation of ER
stress and autophagy
Choi et al. (2018)
Allicin,
s-allyl
cysteine,
–
Various gram-positive species
Both allicin and s-allyl cysteine showed better antimicrobial
activity to treat ear canal and middle ear infections against a
wide range of bacteria
Uzun et al. (2019)
Curcumin
–
Antibacterial activity against
Escherichia coli
and
Staphylococcus aureus
A combination of curcumin with tetracycline showed a
synergistic effect by rupture of the bacterial cell wall
Sukandar et al.
(2018)
424
S. K. Prajapati et al.