Deshpande AA, Shah NH, Rhodes CT, Malick W (1997) Development of a novel
controlled-release system for gastric retention. Pharm Res 14:815–819
Doyle JP, Lyons G, Morris ER (2009) New proposals on “hyperentanglement” of galactomannans:
solution viscosity of fenugreek gum under neutral and alkaline conditions. Food Hydrocoll
23:1501–1510
Eidi A, Eidi M, Sokhteh M (2007) Effect of fenugreek (Trigonella foenum-graecum L) seeds on
serum parameters in normal and streptozotocin-induced diabetic rats. Nutr Res 27:728–733
El Nasri NA, El Tinay AH (2007) Functional properties of fenugreek (Trigonella foenum graecum)
protein concentrate. Food Chem 103:582–589
Elbetieha A, Al-Hamood MH, Al-Kofahi A (1996) Anti-implantation potential of some medicinal
plants in female rats. Arch STD HIV Res 10:181–187
Elzoghby OA, Abd-Elwakil MM, Abd-Elsalam K, Elsayed TM, Hashem Y, Mohamed O (2016)
Natural polymeric nanoparticles for brain-targeting: implications on drug and gene delivery.
Curr Pharm Des 22:3305–3323
Gade R, Murthy TEGK (2014) Effect of hydrophilic and hydrophobic polymers on release kinetics
of metoprolol succinate extended release tablets. AJP 5:101–106
Garg RC (2016) Fenugreek: multiple health benefits. In: Nutraceuticals. Academic Press,
pp 599–617
Garg S, Vermani K, Garg A, Anderson RA, Rencher WB, Zaneveld LJ (2005) Development and
characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel
contraceptive antimicrobial agent. Phar Res 22:584–595
Goyal S, Gupta N, Chatterjee S (2016) Investigating therapeutic potential of Trigonella
foenum-graecum L. as our defense mechanism against several human diseases. J Toxicol
2016:1–10
Haghshenas B, Abdullah N, Nami Y, Radiah D, Rosli R, Khosroushahi Yari (2015a) A
Microencapsulation of probiotic bacteria L actobacillus plantarum 15 HN using
alginate-psyllium-fenugreek polymeric blends. J Appl Microbiol 118:1048–1057
Haghshenas B, Nami Y, Haghshenas M, Barzegari A, Sharifi S, Radiah D, Abdullah N (2015b)
Effect of addition of inulin and fenugreek on the survival of microencapsulated Enterococcus
durans 39C in alginate-psyllium polymeric blends in simulated digestive system and yogurt.
Asian J Pharm Sci 10:350–361
Hao S, Wang Y, Wang B (2014) Sinking-magnetic microparticles prepared by the electrospray
method for enhanced gastric antimicrobial delivery. Mol Pharm 11:1640–1650
He Y, Ding C, Wang X, Wang H, Suo Y (2015) Using response surface methodology to optimize
countercurrent chromatographic separation of polyphenol compounds from fenugreek
(Trigonella foenum-graecum L.) seeds. J Liq Chromatogr Relat Technol 38:29–35
Hefnawy HTM, Ramadan MF (2011) Physicochemical characteristics of soy protein isolate and
fenugreek gum dispersed systems. Int J Food Sci Tech 48:371–377
Hoozemans JJ, O’Banion MK (2005) The role of COX-1 and COX-2 in Alzheimer’s disease
pathology and the therapeutic potentials of non-steroidal anti-inflammatory drugs. CNS Neurol
Disord-Dr 4:307–315
Iurian S, Dinte E, Iuga C, Bogdan C, Spiridon I, Barbu-Tudoran L, Leucuţa SE (2017) The
pharmaceutical applications of a biopolymer isolated from Trigonella foenum-graecum seeds:
focus on the freeze-dried matrix forming capacity. Saudi Pharm J 25:1217–1225
Jian HL, Lin XJ, Zhang WA, Zhang WM, Sun DF, Jiang JX (2014) Characterization of fractional
precipitation behavior of galactomannan gums with ethanol and isopropanol. Food Hydrocoll
40:115–121
Jiang JX, Zhu LW, Zhang WM, Sun RC (2007) Characterization of galactomannan gum from
fenugreek (Trigonella foenum-graecum) seeds and its rheological properties. Int J Polym Mater
56:1145–1154
Kakani RK, Anwer MM (2012) Fenugreek. In Handbook of herbs and spices. Woodhead
Publishing, pp 286–298
404
P. Mishra et al.
controlled-release system for gastric retention. Pharm Res 14:815–819
Doyle JP, Lyons G, Morris ER (2009) New proposals on “hyperentanglement” of galactomannans:
solution viscosity of fenugreek gum under neutral and alkaline conditions. Food Hydrocoll
23:1501–1510
Eidi A, Eidi M, Sokhteh M (2007) Effect of fenugreek (Trigonella foenum-graecum L) seeds on
serum parameters in normal and streptozotocin-induced diabetic rats. Nutr Res 27:728–733
El Nasri NA, El Tinay AH (2007) Functional properties of fenugreek (Trigonella foenum graecum)
protein concentrate. Food Chem 103:582–589
Elbetieha A, Al-Hamood MH, Al-Kofahi A (1996) Anti-implantation potential of some medicinal
plants in female rats. Arch STD HIV Res 10:181–187
Elzoghby OA, Abd-Elwakil MM, Abd-Elsalam K, Elsayed TM, Hashem Y, Mohamed O (2016)
Natural polymeric nanoparticles for brain-targeting: implications on drug and gene delivery.
Curr Pharm Des 22:3305–3323
Gade R, Murthy TEGK (2014) Effect of hydrophilic and hydrophobic polymers on release kinetics
of metoprolol succinate extended release tablets. AJP 5:101–106
Garg RC (2016) Fenugreek: multiple health benefits. In: Nutraceuticals. Academic Press,
pp 599–617
Garg S, Vermani K, Garg A, Anderson RA, Rencher WB, Zaneveld LJ (2005) Development and
characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel
contraceptive antimicrobial agent. Phar Res 22:584–595
Goyal S, Gupta N, Chatterjee S (2016) Investigating therapeutic potential of Trigonella
foenum-graecum L. as our defense mechanism against several human diseases. J Toxicol
2016:1–10
Haghshenas B, Abdullah N, Nami Y, Radiah D, Rosli R, Khosroushahi Yari (2015a) A
Microencapsulation of probiotic bacteria L actobacillus plantarum 15 HN using
alginate-psyllium-fenugreek polymeric blends. J Appl Microbiol 118:1048–1057
Haghshenas B, Nami Y, Haghshenas M, Barzegari A, Sharifi S, Radiah D, Abdullah N (2015b)
Effect of addition of inulin and fenugreek on the survival of microencapsulated Enterococcus
durans 39C in alginate-psyllium polymeric blends in simulated digestive system and yogurt.
Asian J Pharm Sci 10:350–361
Hao S, Wang Y, Wang B (2014) Sinking-magnetic microparticles prepared by the electrospray
method for enhanced gastric antimicrobial delivery. Mol Pharm 11:1640–1650
He Y, Ding C, Wang X, Wang H, Suo Y (2015) Using response surface methodology to optimize
countercurrent chromatographic separation of polyphenol compounds from fenugreek
(Trigonella foenum-graecum L.) seeds. J Liq Chromatogr Relat Technol 38:29–35
Hefnawy HTM, Ramadan MF (2011) Physicochemical characteristics of soy protein isolate and
fenugreek gum dispersed systems. Int J Food Sci Tech 48:371–377
Hoozemans JJ, O’Banion MK (2005) The role of COX-1 and COX-2 in Alzheimer’s disease
pathology and the therapeutic potentials of non-steroidal anti-inflammatory drugs. CNS Neurol
Disord-Dr 4:307–315
Iurian S, Dinte E, Iuga C, Bogdan C, Spiridon I, Barbu-Tudoran L, Leucuţa SE (2017) The
pharmaceutical applications of a biopolymer isolated from Trigonella foenum-graecum seeds:
focus on the freeze-dried matrix forming capacity. Saudi Pharm J 25:1217–1225
Jian HL, Lin XJ, Zhang WA, Zhang WM, Sun DF, Jiang JX (2014) Characterization of fractional
precipitation behavior of galactomannan gums with ethanol and isopropanol. Food Hydrocoll
40:115–121
Jiang JX, Zhu LW, Zhang WM, Sun RC (2007) Characterization of galactomannan gum from
fenugreek (Trigonella foenum-graecum) seeds and its rheological properties. Int J Polym Mater
56:1145–1154
Kakani RK, Anwer MM (2012) Fenugreek. In Handbook of herbs and spices. Woodhead
Publishing, pp 286–298
404
P. Mishra et al.