alginate to prepare ionotropically-gelled microbeads of metformin HCl. These
Assam bora rice starch-alginate microbeads showed a sustained drug releasing
profile over a longer period.
3.3.7 Nanoparticles
The utilization of plant polysaccharides in the designing of nanoparticles is still in
its infancy and relatively few studies are reported where plant polysaccharides have
been investigated for the preparation of nanoparticles. Pitombeira et al. (2015)
prepared nanoparticles using acetylated cashew gum via the self-assembled technique by dialysis. These self-assembled cashew gum-based nanoparticles were
Fig. 3.10 In vitro drug release from various zinc alginate-carboxymethyl cashew gum microbeads
containing isoxsuprine HCl [mean ± S.D., n = 3] (Das et al. 2014; Copyright @ 2014, with
permission from Elsevier B.V.)
Fig. 3.11 The percentages inhibition of paw oedema swelling in carageenan induced rat paw
oedema model for the standard and chitosan-based interpenetrating polymeric network microparticles of aceclofenac at various time intervals (Jana et al. 2013; Copyright @ 2013, with permission
from Elsevier B.V.)
110
A. K. Nayak et al.
Assam bora rice starch-alginate microbeads showed a sustained drug releasing
profile over a longer period.
3.3.7 Nanoparticles
The utilization of plant polysaccharides in the designing of nanoparticles is still in
its infancy and relatively few studies are reported where plant polysaccharides have
been investigated for the preparation of nanoparticles. Pitombeira et al. (2015)
prepared nanoparticles using acetylated cashew gum via the self-assembled technique by dialysis. These self-assembled cashew gum-based nanoparticles were
Fig. 3.10 In vitro drug release from various zinc alginate-carboxymethyl cashew gum microbeads
containing isoxsuprine HCl [mean ± S.D., n = 3] (Das et al. 2014; Copyright @ 2014, with
permission from Elsevier B.V.)
Fig. 3.11 The percentages inhibition of paw oedema swelling in carageenan induced rat paw
oedema model for the standard and chitosan-based interpenetrating polymeric network microparticles of aceclofenac at various time intervals (Jana et al. 2013; Copyright @ 2013, with permission
from Elsevier B.V.)
110
A. K. Nayak et al.