gum with hydroxypropylmethylcellulose to prepare matrix tablets of hydralazine
HCl. These matrix tablets showed a prolonged sustained drug releasing along with
good floating as well as bioadhesive behaviors. Kaleemullah et al. (2017) evaluated
the use of Hibiscus rosa-sinensis leaves mucilage as matrix former and release
retardant excipients in the formulations of sustained release ketoprofen matrix
tablets. The in vitro dissolution studies of formulated ketoprofen matrix tablets
exhibited sustained ketoprofen releasing up to 24 h. Gaikar and Sandhya (2012)
evaluated the tablet binding properties of Aegle marmelos fruit mucilage at different
concentrations in the formulations of paracetamol tablets. Aegle marmelos fruit
mucilage of 3% w/w was found to produce comparable results with starch paste of
10% w/w as tablet binder. Ahuja et al. (2013a) studied tablet binding and disintegrant properties of Mimosa pudica seed mucilage. The tablet binding property
was assessed via the preparation of the paracetamol tablets using Mimosa pudica
seed mucilage (6, 8 and 10% w/w) as tablet binder and compared with the standard
binders (polyvinyl pyrrolidone K25 and gum acacia). Mimosa pudica seed mucilage at 10% (w/w) concentration produced tablets possessing adequate hardness as
well as friability. The tablet disintegrant property was assessed via the preparation
of directly compressed hydrochlorothiazide tablets using Mimosa pudica seed
mucilage of 1–10% (w/w) as disintegrant and compared with the standard disintegrants (Ac-Di-Sol and starch). The Mimosa pudica seed mucilage at 3% (w/w)
concentration showed better disintegrant property of the hydrochlorothiazide
tablets. In a research, Okunlola and Odeku (2011) evaluated tablet binding properties of starches from four Dioscorea species, namely Dioscorea alata, Dioscorea
dumetorum, Dioscorea rotundata, Dioscorea oppositifolia, etc., in chloroquine
phosphate tablet. The results of the research suggested that starches of Dioscorea
alata, and Dioscorea rotundata could be functional for faster disintegration. On the
other hand, starches of Dioscorea oppositifolia and Dioscorea dumetorum could be
useful for the minimizations the tablet defects like capping and lamination in tablet
formulations. Manek et al. (2012) employed the starch extracted from Cyperus
esculentus as binder in formulation of metronidazole tablets. Metronidazole tablets
prepared using 5, 7.5 and 10% Cyperus esculentus starch were compared with
tablets prepared using 10% potato starch. Metronidazole tablets prepared using 10%
Cyperus esculentus starch showed better tablet binding property than others. In a
research, Builders et al. (2013) studied the efficacy of tiger nut starch as direct
compression excipient in the formulations of acetylsalicylic acid tablets and
reported the potential of tiger nut starch as direct compression excipient for the
compressible tablets along with enhanced flow properties and improved disintegration. Recently, Peerapattana et al. (2020) evaluated the potential of spray-dried
glutinous rice starch as direct compression excipient to prepare hydrophilic matrix
tablets of propranolol. The content of spray-dried glutinous rice starch was found to
be influenced the propranolol releasing rate from the matrix tablets, significantly.
3 Plant Polysaccharides in Pharmaceutical Applications
103
HCl. These matrix tablets showed a prolonged sustained drug releasing along with
good floating as well as bioadhesive behaviors. Kaleemullah et al. (2017) evaluated
the use of Hibiscus rosa-sinensis leaves mucilage as matrix former and release
retardant excipients in the formulations of sustained release ketoprofen matrix
tablets. The in vitro dissolution studies of formulated ketoprofen matrix tablets
exhibited sustained ketoprofen releasing up to 24 h. Gaikar and Sandhya (2012)
evaluated the tablet binding properties of Aegle marmelos fruit mucilage at different
concentrations in the formulations of paracetamol tablets. Aegle marmelos fruit
mucilage of 3% w/w was found to produce comparable results with starch paste of
10% w/w as tablet binder. Ahuja et al. (2013a) studied tablet binding and disintegrant properties of Mimosa pudica seed mucilage. The tablet binding property
was assessed via the preparation of the paracetamol tablets using Mimosa pudica
seed mucilage (6, 8 and 10% w/w) as tablet binder and compared with the standard
binders (polyvinyl pyrrolidone K25 and gum acacia). Mimosa pudica seed mucilage at 10% (w/w) concentration produced tablets possessing adequate hardness as
well as friability. The tablet disintegrant property was assessed via the preparation
of directly compressed hydrochlorothiazide tablets using Mimosa pudica seed
mucilage of 1–10% (w/w) as disintegrant and compared with the standard disintegrants (Ac-Di-Sol and starch). The Mimosa pudica seed mucilage at 3% (w/w)
concentration showed better disintegrant property of the hydrochlorothiazide
tablets. In a research, Okunlola and Odeku (2011) evaluated tablet binding properties of starches from four Dioscorea species, namely Dioscorea alata, Dioscorea
dumetorum, Dioscorea rotundata, Dioscorea oppositifolia, etc., in chloroquine
phosphate tablet. The results of the research suggested that starches of Dioscorea
alata, and Dioscorea rotundata could be functional for faster disintegration. On the
other hand, starches of Dioscorea oppositifolia and Dioscorea dumetorum could be
useful for the minimizations the tablet defects like capping and lamination in tablet
formulations. Manek et al. (2012) employed the starch extracted from Cyperus
esculentus as binder in formulation of metronidazole tablets. Metronidazole tablets
prepared using 5, 7.5 and 10% Cyperus esculentus starch were compared with
tablets prepared using 10% potato starch. Metronidazole tablets prepared using 10%
Cyperus esculentus starch showed better tablet binding property than others. In a
research, Builders et al. (2013) studied the efficacy of tiger nut starch as direct
compression excipient in the formulations of acetylsalicylic acid tablets and
reported the potential of tiger nut starch as direct compression excipient for the
compressible tablets along with enhanced flow properties and improved disintegration. Recently, Peerapattana et al. (2020) evaluated the potential of spray-dried
glutinous rice starch as direct compression excipient to prepare hydrophilic matrix
tablets of propranolol. The content of spray-dried glutinous rice starch was found to
be influenced the propranolol releasing rate from the matrix tablets, significantly.
3 Plant Polysaccharides in Pharmaceutical Applications
103