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Fig. 8 SEM of various nucleic acid-nanoparticle constructs; a MNP-APTES, b MNP-APTESGLU, c MNP-APTES-N3, d MNP-APTES-TWJ1, e MNP-APTES-TWJ1-AVIDIN and f MNPAPTES-TWJ2-AVIDIN (5 kV, 100,000 magnification)
(MNP-APTES-TWJ1) (Fig. 8d) to AVIDIN-conjugated matrix (Fig. 8e) manifested
in greater particle sizes (from 45–54 nm to 55–80 nm) and change in morphology
(spherical to cubical). The more complex network accomplished via MTWJ2 is evident from the wider size range of 100–190 nm for the MNP-APTES-TWJ2-AVIDIN
(Fig. 8f).
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