3. Peng K et al (2018) The bioeconomy of microalgal biofuels. In: Energy from microalgae.
Springer, New York, pp 157–169
4. Cheng JJ, Timilsina GR (2011) Status and
barriers of advanced biofuel technologies: a
review. Renew Energy 36(12):3541–3549
5. Singh J, Gu S (2010) Commercialization
potential of microalgae for biofuels production. Renew Sustain Energy Rev 14
(9):2596–2610
6. Banerjee C, Dubey KK, Shukla P (2016) Metabolic engineering of microalgal based biofuel
production: prospects and challenges. Front
Microbiol 7:432
7. Brown LM, Zeiler KG (1993) Aquatic biomass
and carbon dioxide trapping. Energ Conver
Manage 34(9-11):1005–1013
8. Chisti Y (2008) Biodiesel from microalgae
beats bioethanol. Trends Biotechnol 26
(3):126–131
9. Schenk PM et al (2008) Second generation
biofuels: high-efficiency microalgae for biodiesel production. Bioenergy Res 1(1):20–43
10. Greenwell H et al (2010) Placing microalgae
on the biofuels priority list: a review of the
technological challenges. J R Soc Interface
7:703–726
11. Pienkos PT, Darzins A (2009) The promise
and challenges of microalgal-derived biofuels.
Biofuels Bioprod Biorefin 3(4):431–440
12. De Bhowmick G, Koduru L, Sen R (2015)
Metabolic pathway engineering towards
enhancing microalgal lipid biosynthesis for biofuel application—a review. Renew Sustain
Energy Rev 50:1239–1253
13. Ho S-H et al (2014) Perspectives on engineering strategies for improving biofuel production
from microalgae—a critical review. Biotechnol
Adv 32(8):1448–1459
14. Zhang F, Rodriguez S, Keasling JD (2011)
Metabolic engineering of microbial pathways
for advanced biofuels production. Curr Opin
Biotechnol 22(6):775–783
15. Liu D, Evans T, Zhang F (2015) Applications
and advances of metabolite biosensors for metabolic engineering. Metab Eng 31:35–43
16. Majidian P, Tabatabaei M, Zeinolabedini M,
Naghshbandi MP, Chisti Y (2018) Metabolic
engineering of microorganisms for biofuel production. Renew Sustain Energy Rev
82:3863–3885
17. Jagadevan S et al (2018) Recent developments
in synthetic biology and metabolic engineering
in microalgae towards biofuel production. Biotechnol Biofuels 11(1):185
18. Costa JAV, De Morais MG (2011) The role of
biochemical engineering in the production of
biofuels from microalgae. Bioresour Technol
102(1):2–9
19. Zorrilla Lo ´pez U et al (2013) Engineering metabolic pathways in plants by multigene transformation. Int J Dev Biol 57(6–8):565–576
20. Chisti Y (2007) Biodiesel from microalgae.
Biotechnol Adv 25(3):294–306
21. Gaurav N et al (2017) Utilization of bioresources for sustainable biofuels: a review.
Renew Sustain Energy Rev 73:205–214
22. Bellou S et al (2014) Microalgal lipids biochemistry and biotechnological perspectives.
Biotechnol Adv 32(8):1476–1493
23. Yu W-L et al (2011) Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. Microb Cell Fact 10
(1):91
24. Radakovits R et al (2010) Genetic engineering
of algae for enhanced biofuel production.
Eukaryot Cell 9(4):486–501
25. Post-Beittenmiller D, Jaworski J, Ohlrogge J
(1991) In vivo pools of free and acylated acyl
carrier proteins in spinach. Evidence for sites of
regulation of fatty acid biosynthesis. J Biol
Chem 266(3):1858–1865
26. Post-Beittenmiller D, Roughan G, Ohlrogge
JB (1992) Regulation of plant fatty acid biosynthesis: analysis of acyl-coenzyme A and acylacyl carrier protein substrate pools in spinach
and pea chloroplasts. Plant Physiol 100
(2):923–930
27. Chang W-C, Zheng H-Q, Chen C-NN (2016)
Comparative transcriptome analysis reveals a
potential photosynthate partitioning mechanism
between lipid and starch biosynthetic pathways
in green microalgae. Algal Res 16:54–62
28. Liang M-H, Jiang J-G (2013) Advancing oleaginous microorganisms to produce lipid via
metabolic engineering technology. Prog Lipid
Res 52(4):395–408
29. Dunahay TG et al (1996) Manipulation of
microalgal lipid production using genetic engineering. Appl Biochem Biotechnol 57(1):223
30. Sheehan J et al (1998) A look back at the US
Department of Energy’s aquatic species program: biodiesel from algae. National Renewable Energy Laboratory, Golden, p 328
31. Gomma AE et al (2015) Improvement in oil
production by increasing malonyl-CoA and
glycerol-3-phosphate pools in scenedesmus
quadricauda. Indian J Microbiol 55
(4):447–455
32. Zhang X, Agrawal A, San KY (2012) Improving fatty acid production in Escherichia coli
through the overexpression of malonyl
coA-Acyl carrier protein transacylase. Biotechnol Prog 28(1):60–65
Metabolic Engineering of Microalgae
169
Springer, New York, pp 157–169
4. Cheng JJ, Timilsina GR (2011) Status and
barriers of advanced biofuel technologies: a
review. Renew Energy 36(12):3541–3549
5. Singh J, Gu S (2010) Commercialization
potential of microalgae for biofuels production. Renew Sustain Energy Rev 14
(9):2596–2610
6. Banerjee C, Dubey KK, Shukla P (2016) Metabolic engineering of microalgal based biofuel
production: prospects and challenges. Front
Microbiol 7:432
7. Brown LM, Zeiler KG (1993) Aquatic biomass
and carbon dioxide trapping. Energ Conver
Manage 34(9-11):1005–1013
8. Chisti Y (2008) Biodiesel from microalgae
beats bioethanol. Trends Biotechnol 26
(3):126–131
9. Schenk PM et al (2008) Second generation
biofuels: high-efficiency microalgae for biodiesel production. Bioenergy Res 1(1):20–43
10. Greenwell H et al (2010) Placing microalgae
on the biofuels priority list: a review of the
technological challenges. J R Soc Interface
7:703–726
11. Pienkos PT, Darzins A (2009) The promise
and challenges of microalgal-derived biofuels.
Biofuels Bioprod Biorefin 3(4):431–440
12. De Bhowmick G, Koduru L, Sen R (2015)
Metabolic pathway engineering towards
enhancing microalgal lipid biosynthesis for biofuel application—a review. Renew Sustain
Energy Rev 50:1239–1253
13. Ho S-H et al (2014) Perspectives on engineering strategies for improving biofuel production
from microalgae—a critical review. Biotechnol
Adv 32(8):1448–1459
14. Zhang F, Rodriguez S, Keasling JD (2011)
Metabolic engineering of microbial pathways
for advanced biofuels production. Curr Opin
Biotechnol 22(6):775–783
15. Liu D, Evans T, Zhang F (2015) Applications
and advances of metabolite biosensors for metabolic engineering. Metab Eng 31:35–43
16. Majidian P, Tabatabaei M, Zeinolabedini M,
Naghshbandi MP, Chisti Y (2018) Metabolic
engineering of microorganisms for biofuel production. Renew Sustain Energy Rev
82:3863–3885
17. Jagadevan S et al (2018) Recent developments
in synthetic biology and metabolic engineering
in microalgae towards biofuel production. Biotechnol Biofuels 11(1):185
18. Costa JAV, De Morais MG (2011) The role of
biochemical engineering in the production of
biofuels from microalgae. Bioresour Technol
102(1):2–9
19. Zorrilla Lo ´pez U et al (2013) Engineering metabolic pathways in plants by multigene transformation. Int J Dev Biol 57(6–8):565–576
20. Chisti Y (2007) Biodiesel from microalgae.
Biotechnol Adv 25(3):294–306
21. Gaurav N et al (2017) Utilization of bioresources for sustainable biofuels: a review.
Renew Sustain Energy Rev 73:205–214
22. Bellou S et al (2014) Microalgal lipids biochemistry and biotechnological perspectives.
Biotechnol Adv 32(8):1476–1493
23. Yu W-L et al (2011) Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. Microb Cell Fact 10
(1):91
24. Radakovits R et al (2010) Genetic engineering
of algae for enhanced biofuel production.
Eukaryot Cell 9(4):486–501
25. Post-Beittenmiller D, Jaworski J, Ohlrogge J
(1991) In vivo pools of free and acylated acyl
carrier proteins in spinach. Evidence for sites of
regulation of fatty acid biosynthesis. J Biol
Chem 266(3):1858–1865
26. Post-Beittenmiller D, Roughan G, Ohlrogge
JB (1992) Regulation of plant fatty acid biosynthesis: analysis of acyl-coenzyme A and acylacyl carrier protein substrate pools in spinach
and pea chloroplasts. Plant Physiol 100
(2):923–930
27. Chang W-C, Zheng H-Q, Chen C-NN (2016)
Comparative transcriptome analysis reveals a
potential photosynthate partitioning mechanism
between lipid and starch biosynthetic pathways
in green microalgae. Algal Res 16:54–62
28. Liang M-H, Jiang J-G (2013) Advancing oleaginous microorganisms to produce lipid via
metabolic engineering technology. Prog Lipid
Res 52(4):395–408
29. Dunahay TG et al (1996) Manipulation of
microalgal lipid production using genetic engineering. Appl Biochem Biotechnol 57(1):223
30. Sheehan J et al (1998) A look back at the US
Department of Energy’s aquatic species program: biodiesel from algae. National Renewable Energy Laboratory, Golden, p 328
31. Gomma AE et al (2015) Improvement in oil
production by increasing malonyl-CoA and
glycerol-3-phosphate pools in scenedesmus
quadricauda. Indian J Microbiol 55
(4):447–455
32. Zhang X, Agrawal A, San KY (2012) Improving fatty acid production in Escherichia coli
through the overexpression of malonyl
coA-Acyl carrier protein transacylase. Biotechnol Prog 28(1):60–65
Metabolic Engineering of Microalgae
169