491
that the crude extract containing a concentration of 225 8 g/mL exhibited the highest zone of inhibition of 27 mm against Klebsilla pneumonia while concentration
containing 75 8 g/mL exhibited the least antibacterial effect on Staphylococcus epidermidis. Their study shows that the methanolic root extract of Caesalpinia pulcherrima could be used as an antibacterial agent.
Sultana et al. (2010), reported the antimicrobial, cytotoxicity and free radical
scavenging potential of methanolic extract of Glycyrrhiza glabra which belong to
the family of Fabaceae. The result obtained shows that the extract of Glycyrrhiza
glabra inhibited all the test microorganisms with the exception of Pseudomonas
aeruginosa. The highest sensitivity was observed on Staphylococcus aureus with a
zone of inhibition of 22 mm while cytotoxic activity had LC 50 value of 0.771 μg/ml
and free radical scavenging activity had IC 50 values of 87.152 μg/ml.
Chanda et al. (2010) evaluated the antibacterial effectiveness of fruit rind and the
seeds of nutraceutical plants which belongs to Fabaceae family. The antimicrobial
assessment was performed using agar well diffusion techniques against four gramnegative and four gram-positive bacteria. The result shows that the crude extract
obtained from the Fabaceae family exhibited a higher antibacterial activity on grampositive bacteria when compared to gram-negative bacteria.
Arabi and Sardari (2010) evaluated the antifungal effect of a medicinal plant that
belongs to the family of Fabaceae obtained from South and north of Iran. Some of
the medicinal plants that belong to Fabaceae used during this study were Astragalus
stepporum, Taverniera cuneifolia, Dalbergia sissoo, Ammodendron persicum,
Lathyrus pratensis, Sophora alopecuroides, Oreophysa microphyalla respectively.
The active component was extracted using the Percolation technique with 80% ethanol. The antifungal effect was performed using broth microdilution against
Aspergillus fumigatus AF 293, Candida albicans ATCC 10231, and Asperigillus
niger ATCC 16404 respectively. The result revealed that all the plants from Fabaceae
utilized during this experiment exhibited an antimicrobial effect against at least one
of the tested isolates. The study validates the significant of the Fabaceae plant as a
therapeutic agent for the management of pathogenic fungi.
Aung (2011) assessed the antimicrobial effectiveness and the level of the phytochemical component present in Sesbania grandiflora L. from the family Fabaceae.
The chloroform extract exhibit more antimicrobial activity against all the tested
isolates most importantly on Pseudomonas aeruginosa. The antimicrobial activity
demonstrated by the crude extract from the leaves of Sesbania grandiflora might be
linked to the presence of various phytochemical constituents like α-amino acid,
reducing sugar, phenolic compound, terpenoid/steroid, carbohydrate, tannin, flavonoid, saponin, glycoside, and glycoside.
Chaurasia and Saxena (2012), reported the antibacterial effectiveness of 4 different green beans. The aqueous extract from the various green beans were extracted
from Vicia faba (broad beans; stem), Vigna unguiculata (cowpea; lobia), Phaseolus
vulgaris (French beans), Cyamopsis tetragonoloba (cluster beans; guar) and were
evaluated against two human pathogenic bacteria which were Bacillus subtilis
(gram positive) and Escherichia coli (gram negative). The antimicrobial assay was
performed using disc diffusion techniques. The effectiveness of the aqueous extract
22 Health Benefits of Isoflavones Found Exclusively of Plants of the Fabaceae Family
that the crude extract containing a concentration of 225 8 g/mL exhibited the highest zone of inhibition of 27 mm against Klebsilla pneumonia while concentration
containing 75 8 g/mL exhibited the least antibacterial effect on Staphylococcus epidermidis. Their study shows that the methanolic root extract of Caesalpinia pulcherrima could be used as an antibacterial agent.
Sultana et al. (2010), reported the antimicrobial, cytotoxicity and free radical
scavenging potential of methanolic extract of Glycyrrhiza glabra which belong to
the family of Fabaceae. The result obtained shows that the extract of Glycyrrhiza
glabra inhibited all the test microorganisms with the exception of Pseudomonas
aeruginosa. The highest sensitivity was observed on Staphylococcus aureus with a
zone of inhibition of 22 mm while cytotoxic activity had LC 50 value of 0.771 μg/ml
and free radical scavenging activity had IC 50 values of 87.152 μg/ml.
Chanda et al. (2010) evaluated the antibacterial effectiveness of fruit rind and the
seeds of nutraceutical plants which belongs to Fabaceae family. The antimicrobial
assessment was performed using agar well diffusion techniques against four gramnegative and four gram-positive bacteria. The result shows that the crude extract
obtained from the Fabaceae family exhibited a higher antibacterial activity on grampositive bacteria when compared to gram-negative bacteria.
Arabi and Sardari (2010) evaluated the antifungal effect of a medicinal plant that
belongs to the family of Fabaceae obtained from South and north of Iran. Some of
the medicinal plants that belong to Fabaceae used during this study were Astragalus
stepporum, Taverniera cuneifolia, Dalbergia sissoo, Ammodendron persicum,
Lathyrus pratensis, Sophora alopecuroides, Oreophysa microphyalla respectively.
The active component was extracted using the Percolation technique with 80% ethanol. The antifungal effect was performed using broth microdilution against
Aspergillus fumigatus AF 293, Candida albicans ATCC 10231, and Asperigillus
niger ATCC 16404 respectively. The result revealed that all the plants from Fabaceae
utilized during this experiment exhibited an antimicrobial effect against at least one
of the tested isolates. The study validates the significant of the Fabaceae plant as a
therapeutic agent for the management of pathogenic fungi.
Aung (2011) assessed the antimicrobial effectiveness and the level of the phytochemical component present in Sesbania grandiflora L. from the family Fabaceae.
The chloroform extract exhibit more antimicrobial activity against all the tested
isolates most importantly on Pseudomonas aeruginosa. The antimicrobial activity
demonstrated by the crude extract from the leaves of Sesbania grandiflora might be
linked to the presence of various phytochemical constituents like α-amino acid,
reducing sugar, phenolic compound, terpenoid/steroid, carbohydrate, tannin, flavonoid, saponin, glycoside, and glycoside.
Chaurasia and Saxena (2012), reported the antibacterial effectiveness of 4 different green beans. The aqueous extract from the various green beans were extracted
from Vicia faba (broad beans; stem), Vigna unguiculata (cowpea; lobia), Phaseolus
vulgaris (French beans), Cyamopsis tetragonoloba (cluster beans; guar) and were
evaluated against two human pathogenic bacteria which were Bacillus subtilis
(gram positive) and Escherichia coli (gram negative). The antimicrobial assay was
performed using disc diffusion techniques. The effectiveness of the aqueous extract
22 Health Benefits of Isoflavones Found Exclusively of Plants of the Fabaceae Family