440
Maeda H, Hosokawa M, Sahima T, Funayama K, Miyashita K (2005) Fucoxanthin from edible
seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in whiteadipose tissue. Biochem Biophys Res Comm 332:392–397
Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, Miyashita K (2006) Fucoxanthin
and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. Int J Mol
Med 18:147–152
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K (2007a) Effect of medium-chain
Triacylglycerols on anti-obesity effect of Fucoxanthin. J Oleo Sci 56(12):615–621
Maeda H, Hosokawa M, Sashima T, Miyashita K (2007b) Dietary combination of Fucoxanthin and
fish oil attenuates the weight gain of white Adopose tissue and decrease blood glucose in obese/
diabetic KK-Ay mice. J Agric Food Chem 55:7701–7706
Maeda H, Hosokawa M, Sashima T, Murakami-Funayama K, Miyashita K (2009) Anti-obesity
and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model.
Mol Med Rep 2:897–902
Masetto A, Flores-Cotera LB, Diaz C, Langley E, Sanchez S (2001) Application of a complete
factorial design for the production of Zeaxanthin by Flavobacterium sp. J Biosci Bioeng
92(1):55–58
Mattea F, Martin A, Cocero MJ (2009) Carotenoid processing with supercritical fluids. J Food Eng
93:255–265
Mezzomo N, Ferreira SRS (2016) Carotenoids functionality, sources, and processing by supercritical technology: a review. J Chem, Article ID 3164312
Michael MD, Kulkarni RN, Postic C et al (2000) Loss of insulin signaling in hepatocytes leads to
severe insulin resistance and progressive hepatic dysfunction. Mol Cell 6:87–97
Mitri K, Shegokar R, Gohla S, Anselmi C, Müller RH (2011) Lipid nanocarriers for dermal
delivery of lutein: preparation, characterization, stability and performance. Int J Pharm
414(1–2):267–275
Miyashita K (2006) Seaweed carotenoid, Fucoxanthin, with highly bioactive and nutritional activities. J Mar Biosci Biotechnol 1(1):48–58
Nagarajan J, Ramanan RN, Raghunandan ME, Galanakis CM Krishnamurth NP (2017). Chapter
8: Nutraceutical and functional food components. Elsevier Inc., pp 259–296
Najm W, Lie D (2008) Dietary supplements commonly used for prevention. Prim Care 35:749–767
Naziri D, Hamidi M, Hassanzadeh S, Tarhriz V, Zanjani BM, Nazemyieh H, Hejazi MS (2014)
Analysis of carotenoid production by Halorubrum sp. TBZ126; an extremely halophilic
archeon from Urmia Lake. Adv Pharm Bull 4(1):61
Nelis JH, DeLeenheer PA (1991) Microbial sources of carotenoid pigments used in foods and
feeds. J Appl Bacteriol 70:181–191
Nishikawa S, Hosokawa M, Miyashita K (2012) Fucoxanthin promotes translocation and induction
of glucose transporter 4 in skeletal muscles of diabetic/obese KK-A(y) mice. Phytomedicine
19:389–394
Nishino H, Murakoshi M, Ii T, Takemura M, Kuchide M, Kanazawa M, Mou XY, Wada S, Masuda
M, Ohsaka Y, Yogosawa S, Satomi Y, Jinno K (2002) Carotenoids in cancer chemoprevention.
Cancer Metastasis Rev 21:257–264
Nishino H, Murakoshi M, Tokuda H, Satomi Y (2009) Cancer prevention by carotenoids. Arch
Biochem Biophys 483:165–168
Ohgami K, Shiratori K, Kotake S, Nishida T, Mizuki N, Yazawa K, Ohno S (2003) Effects of astaxanthin on lipopolysaccharide induced inflammation in vitro and in vivo. Investig Ophthalmol
Vis Sci 44:2694–2701
Okada T, Nakai M, Maeda H, Hosokawa M, Sashima T, Miyashita K (2008) Suppressive effect of
Neoxanthin on the differentiation of 3T3-L1 adipose cells. J Oleo Sci 57(6):345–351
Olson JA (1987) Recommended dietary intakes (RDI) of vitamin A in humans. Am J Clin Nutr
45(4):704–7l6
Ondrey F (2009) Peroxisome proliferator-activated receptor-γ pathway targeting in carcinogenesis: implications for chemoprevention. Clin Cancer Res 15:2–8
A. Olatunde et al.
Maeda H, Hosokawa M, Sahima T, Funayama K, Miyashita K (2005) Fucoxanthin from edible
seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in whiteadipose tissue. Biochem Biophys Res Comm 332:392–397
Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, Miyashita K (2006) Fucoxanthin
and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. Int J Mol
Med 18:147–152
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K (2007a) Effect of medium-chain
Triacylglycerols on anti-obesity effect of Fucoxanthin. J Oleo Sci 56(12):615–621
Maeda H, Hosokawa M, Sashima T, Miyashita K (2007b) Dietary combination of Fucoxanthin and
fish oil attenuates the weight gain of white Adopose tissue and decrease blood glucose in obese/
diabetic KK-Ay mice. J Agric Food Chem 55:7701–7706
Maeda H, Hosokawa M, Sashima T, Murakami-Funayama K, Miyashita K (2009) Anti-obesity
and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model.
Mol Med Rep 2:897–902
Masetto A, Flores-Cotera LB, Diaz C, Langley E, Sanchez S (2001) Application of a complete
factorial design for the production of Zeaxanthin by Flavobacterium sp. J Biosci Bioeng
92(1):55–58
Mattea F, Martin A, Cocero MJ (2009) Carotenoid processing with supercritical fluids. J Food Eng
93:255–265
Mezzomo N, Ferreira SRS (2016) Carotenoids functionality, sources, and processing by supercritical technology: a review. J Chem, Article ID 3164312
Michael MD, Kulkarni RN, Postic C et al (2000) Loss of insulin signaling in hepatocytes leads to
severe insulin resistance and progressive hepatic dysfunction. Mol Cell 6:87–97
Mitri K, Shegokar R, Gohla S, Anselmi C, Müller RH (2011) Lipid nanocarriers for dermal
delivery of lutein: preparation, characterization, stability and performance. Int J Pharm
414(1–2):267–275
Miyashita K (2006) Seaweed carotenoid, Fucoxanthin, with highly bioactive and nutritional activities. J Mar Biosci Biotechnol 1(1):48–58
Nagarajan J, Ramanan RN, Raghunandan ME, Galanakis CM Krishnamurth NP (2017). Chapter
8: Nutraceutical and functional food components. Elsevier Inc., pp 259–296
Najm W, Lie D (2008) Dietary supplements commonly used for prevention. Prim Care 35:749–767
Naziri D, Hamidi M, Hassanzadeh S, Tarhriz V, Zanjani BM, Nazemyieh H, Hejazi MS (2014)
Analysis of carotenoid production by Halorubrum sp. TBZ126; an extremely halophilic
archeon from Urmia Lake. Adv Pharm Bull 4(1):61
Nelis JH, DeLeenheer PA (1991) Microbial sources of carotenoid pigments used in foods and
feeds. J Appl Bacteriol 70:181–191
Nishikawa S, Hosokawa M, Miyashita K (2012) Fucoxanthin promotes translocation and induction
of glucose transporter 4 in skeletal muscles of diabetic/obese KK-A(y) mice. Phytomedicine
19:389–394
Nishino H, Murakoshi M, Ii T, Takemura M, Kuchide M, Kanazawa M, Mou XY, Wada S, Masuda
M, Ohsaka Y, Yogosawa S, Satomi Y, Jinno K (2002) Carotenoids in cancer chemoprevention.
Cancer Metastasis Rev 21:257–264
Nishino H, Murakoshi M, Tokuda H, Satomi Y (2009) Cancer prevention by carotenoids. Arch
Biochem Biophys 483:165–168
Ohgami K, Shiratori K, Kotake S, Nishida T, Mizuki N, Yazawa K, Ohno S (2003) Effects of astaxanthin on lipopolysaccharide induced inflammation in vitro and in vivo. Investig Ophthalmol
Vis Sci 44:2694–2701
Okada T, Nakai M, Maeda H, Hosokawa M, Sashima T, Miyashita K (2008) Suppressive effect of
Neoxanthin on the differentiation of 3T3-L1 adipose cells. J Oleo Sci 57(6):345–351
Olson JA (1987) Recommended dietary intakes (RDI) of vitamin A in humans. Am J Clin Nutr
45(4):704–7l6
Ondrey F (2009) Peroxisome proliferator-activated receptor-γ pathway targeting in carcinogenesis: implications for chemoprevention. Clin Cancer Res 15:2–8
A. Olatunde et al.