438
Gärtner C, Stahl W, Sies H (1997) Lycopene is more bioavailable from tomato paste than from
fresh tomatoes. Am J Clin Nutr 66:116–122
Gijsbers L, van Eekelen HD, de Haan LH et al (2013) Induction of peroxisome proliferatoractivated receptor γ (PPARγ)-mediated gene expression by tomato (Solanum lycopersicum L.)
extracts. J Agric Food Chem 61:3419–3427
Granado F, Olmedilla B, Blanco I (2003) Nutritional and clinical relevance of lutein in human
health. Br J Nutr 90(3):487–502
Grether-Beck S, Marini A, Jaenicke T, Stahl W, Krutmann J (2017) Molecular evidence that
oral supplementation with lycopene or lutein protects human skin against ultraviolet radiation: results from a double-blinded, placebo-controlled, crossover study. Br J Dermatol
176(5):1231–1240
Hammond BR Jr, Renz LM (2013) Carotenoids. Adv Nutr 4:474–476. https://doi.org/10.3945/
an.113.004028
Han S, Roman J (2007) Peroxisome proliferator-activated receptor γ: a novel target for cancer
therapeutics? Anti-Cancer Drugs 18:237–244
Handelman GJ (2001) The evolving role of carotenoids in human biochemistry. Nutrition
17(10):818–822
Harari A, Harats D, Marko D, Shaish A (2008) A 9-cis β-carotene-enriched diet inhibits atherogenesis and fatty liver formation in LDL receptor knockout mice. J Nutr 138:1923–1930
Heber D, Lu QY (2002) Overview of mechanisms of action of lycopene. Exp Biol Med (Maywood)
227:920–923
Hosokawa M, Wanazaki S, Miyauchi K, Kurihara H, Kohno H, Kawabata J, Odashima S,
Takahashi K (1999) Apoptosis-inducing effect of Fucoxanthin on human Leukemia cell Line
HL-60. Food Sci Technol Res 5(3):243–246
Hosokawa M, Kudo M, Maeda H, Kohno H, Tanaka T, Miyashita K (2004) Fucoxanthin induces
apoptosis and enhances the antiproliverative effect of the PPARγ ligand, troglitazone, on colon
cancer cells. Biochim Biophys Acta 1675:113–119
Hosokawa M, Miyashita T, Nishikawa S, Emi S, Tsukui T, Beppu F, Okada T, Miyashita K (2010)
Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/
obese KK-Ay mice. Arch Biochem Biophys 504:17–25
Hozawa A, Steffes DR Jr, Jacobs MW, Gross MD, Steffen LM, Lee DH (2006) Associations
of serum carotenoid concentrations with the development of diabetes and with insulin concentration: interaction with smoking: the coronary artery risk development in young adults
(CARDIA) study. Am J Epidemiol 163:929–937
Hozawa A, Jacobs JDR, Steffes MW, Gross MD, Steffen LM, Lee DH (2009) Circulating carotenoid concentrations and incident hypertension: the coronary artery risk development in young
adults (CARDIA) study. J Hypertens 27:237–224
Hozumi M, Murata T, Morinobu T, Manago M, Kuno T, Tokuda M, Konishi K, Mingci Z, Tamai H
(1998) Plasma beta-carotene retinol, and alpha-tocopherol levels in relation to glycemic control of children with insulin-dependent diabetes mellitus. J Nutr Sci Vitaminol 44:1–9
Hu MY, Li YL, Jiang CH, Liu ZQ, Qu SL, Huang YM (2008) Comparison of lycopene and fluvastatin effects on atherosclerosis induced by a high-fat diet in rabbits. Nutrition 24:1030–1038
Hubacek JA, Bobkova D (2006) Role of cholesterol 7alpha-hydroxylase (CYP7A1) in nutrigenetics and pharmacogenetics of cholesterol lowering. Mol Diagn Ther 10:93–10
Hussein G, Nakagawa T, Goto H, Shimada Y, Matsumoto K, Sankawa U, Watanabe H (2007)
Astaxanthin ameliorates features of metabolic syndrome in SHR/NDmcr-cp. Life Sci
80:522–529
Ikeuchi M, Koyama T, Takahashi J, Yazawa K (2007) Effects of Astaxanthin in obese mice fed a
high-fat diets. Biosci Biotechnol Biochem 71(4):839–899
Imamura T, Bando N, Yamanishi R (2006) β-carotene modulates the immunological function of
RAW264, a murine macrophage cell Line, by enhancing the level of intracellular glutathione.
Biosci Biotechnol Biochem 70(9):2112–2120
A. Olatunde et al.
Gärtner C, Stahl W, Sies H (1997) Lycopene is more bioavailable from tomato paste than from
fresh tomatoes. Am J Clin Nutr 66:116–122
Gijsbers L, van Eekelen HD, de Haan LH et al (2013) Induction of peroxisome proliferatoractivated receptor γ (PPARγ)-mediated gene expression by tomato (Solanum lycopersicum L.)
extracts. J Agric Food Chem 61:3419–3427
Granado F, Olmedilla B, Blanco I (2003) Nutritional and clinical relevance of lutein in human
health. Br J Nutr 90(3):487–502
Grether-Beck S, Marini A, Jaenicke T, Stahl W, Krutmann J (2017) Molecular evidence that
oral supplementation with lycopene or lutein protects human skin against ultraviolet radiation: results from a double-blinded, placebo-controlled, crossover study. Br J Dermatol
176(5):1231–1240
Hammond BR Jr, Renz LM (2013) Carotenoids. Adv Nutr 4:474–476. https://doi.org/10.3945/
an.113.004028
Han S, Roman J (2007) Peroxisome proliferator-activated receptor γ: a novel target for cancer
therapeutics? Anti-Cancer Drugs 18:237–244
Handelman GJ (2001) The evolving role of carotenoids in human biochemistry. Nutrition
17(10):818–822
Harari A, Harats D, Marko D, Shaish A (2008) A 9-cis β-carotene-enriched diet inhibits atherogenesis and fatty liver formation in LDL receptor knockout mice. J Nutr 138:1923–1930
Heber D, Lu QY (2002) Overview of mechanisms of action of lycopene. Exp Biol Med (Maywood)
227:920–923
Hosokawa M, Wanazaki S, Miyauchi K, Kurihara H, Kohno H, Kawabata J, Odashima S,
Takahashi K (1999) Apoptosis-inducing effect of Fucoxanthin on human Leukemia cell Line
HL-60. Food Sci Technol Res 5(3):243–246
Hosokawa M, Kudo M, Maeda H, Kohno H, Tanaka T, Miyashita K (2004) Fucoxanthin induces
apoptosis and enhances the antiproliverative effect of the PPARγ ligand, troglitazone, on colon
cancer cells. Biochim Biophys Acta 1675:113–119
Hosokawa M, Miyashita T, Nishikawa S, Emi S, Tsukui T, Beppu F, Okada T, Miyashita K (2010)
Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/
obese KK-Ay mice. Arch Biochem Biophys 504:17–25
Hozawa A, Steffes DR Jr, Jacobs MW, Gross MD, Steffen LM, Lee DH (2006) Associations
of serum carotenoid concentrations with the development of diabetes and with insulin concentration: interaction with smoking: the coronary artery risk development in young adults
(CARDIA) study. Am J Epidemiol 163:929–937
Hozawa A, Jacobs JDR, Steffes MW, Gross MD, Steffen LM, Lee DH (2009) Circulating carotenoid concentrations and incident hypertension: the coronary artery risk development in young
adults (CARDIA) study. J Hypertens 27:237–224
Hozumi M, Murata T, Morinobu T, Manago M, Kuno T, Tokuda M, Konishi K, Mingci Z, Tamai H
(1998) Plasma beta-carotene retinol, and alpha-tocopherol levels in relation to glycemic control of children with insulin-dependent diabetes mellitus. J Nutr Sci Vitaminol 44:1–9
Hu MY, Li YL, Jiang CH, Liu ZQ, Qu SL, Huang YM (2008) Comparison of lycopene and fluvastatin effects on atherosclerosis induced by a high-fat diet in rabbits. Nutrition 24:1030–1038
Hubacek JA, Bobkova D (2006) Role of cholesterol 7alpha-hydroxylase (CYP7A1) in nutrigenetics and pharmacogenetics of cholesterol lowering. Mol Diagn Ther 10:93–10
Hussein G, Nakagawa T, Goto H, Shimada Y, Matsumoto K, Sankawa U, Watanabe H (2007)
Astaxanthin ameliorates features of metabolic syndrome in SHR/NDmcr-cp. Life Sci
80:522–529
Ikeuchi M, Koyama T, Takahashi J, Yazawa K (2007) Effects of Astaxanthin in obese mice fed a
high-fat diets. Biosci Biotechnol Biochem 71(4):839–899
Imamura T, Bando N, Yamanishi R (2006) β-carotene modulates the immunological function of
RAW264, a murine macrophage cell Line, by enhancing the level of intracellular glutathione.
Biosci Biotechnol Biochem 70(9):2112–2120
A. Olatunde et al.