409
Garjani A, Tila D, Hamedeyazdan S, Vaez H, Rameshrad M, Pashaii M, Fathiazad F (2017) An
investigation on cardioprotective potential of Marrubium vulgare aqueous fraction against
ischaemia-reperfusion injury in isolated rat heart. Folia Morphol (Warsz) 76:361–371
Gordon NC, Wareham DW (2010) Antimicrobial activity of the green tea polyphenols
(−)-epigallocatechin- 3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia. Int J Antimicrob Agents 36:129–131
Guillermo-Gormaz J, Quintremil S, Rodrigo R (2015) Cardiovascular disease: a target for the
pharmacological effects of quercetin. Curr Top Med Chem 15(17):1735–1742
Han X, Shen T, Lou H (2007) Dietary polyphenols and their biological significance. Int J Mol Sci
8:950–988
Han X, Gao S, Cheng Y, Sun Y, Liu W, Tang L, Ren D (2012) Protective effect of naringenin-7O- glucoside against oxidative stress induced by doxorubicin in H9c2 cardiomyocytes. Biosci
Trends 6:19–25
Harikumar KB, Aggarwal BB (2008) Resveratrol: a multitargeted agent for age-associated chronic
diseases. Cell Cycle 7(8):1020–1035
Hashemzaei M, Far AD, Yari A, Heravi RE, Tabrizian K, Taghdisi SM, Sadegh SE, Tsarouhas K,
Kouretas D, Tzanakakis G (2017) Anticancer and apoptosis-inducing effects of quercetin in
vitro and in vivo. Oncol Rep 38:819–828
Heim KE, Tagliaferro AR, Bobilya DJ (2002) Flavonoid antioxidants: chemistry, metabolism and
structure-activity relationships. J Nutr Biochem 13:572–584
Hisanaga A, Mukai R, Sakao K, Terao J, Hou DX (2016) Anti-inflammatory effects and molecular
mechanisms of 8-Prenyl quercetin. Mol Nutr Food Res 60(5):1020–1032
Hong J, Smith TJ, Ho CT, August DA, Yang C (2001) Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in
human colon mucosa and colon tumor tissues. Biochem Pharmacol 62:1175–1183
Hooper L, Kroon PA, Rimm EB, Cohn JS, Harvey I, Le Cornu KA, Ryder JJ, Hall WL, Cassidy A
(2008) Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials. Am J Clin Nutr 88:38–50
Hosseinzadeh H, Nassiri-Asl M (2014) Review of the protective effects of Rutin on the metabolic
function as an important dietary flavonoid. J Endocrinol Investig 37(9):783–788
Huang C-Y, Ju D-T, Chang C-F, Reddy PM, Velmurugan BK (2017) A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer. Biomedicine
(Taipei) 7(4):23
Ichihashi M, Ueda M, Budiyanto A, Bito T, Oka M, Fukunaga M, Tsuru K, Horikawa T (2003)
UV-induced skin damage. Toxicology 189:21–39
Ide H, Lu Y, Noguchi T, Muto S, Okada H, Kawato S, Horie S (2018) Modulation of AKR1C2
by curcumin decreases testosterone production in prostate cancer. Cancer Sci 109:1230–1238
Jarial R, Thakur S, Sakinah M, Zularisam AW, Sharad A, Kanwar SS, Singh L (2018) Potent anticancer, antioxidant and antibacterial activities of isolated flavonoids from Asplenium nidus. J
King Saud Univ-Sci 30:185–192
Kano M, Kubota N, Masuoka N, Hori T, Miyazaki K, Ishikawa F (2016) Oral administration
of fermented soymilk products protects the skin of hairless mice against ultraviolet damage.
Nutrients 8:514
Katiyar SK, Mantena SK, Meeran SM (2011) Silymarin protects epidermal keratinocytes from
ultraviolet radiation-induced apoptosis and DNA damage by nucleotide excision repair mechanism. PLoS One 6:e21410
Khoo HE, Azlan A, Tang ST, Lim SM (2017) Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits. Food Nutr Res
61(1):1361779
Kim JA, Jung WS, Chun SC, Yu CY, Ma KH, Gwag JG, Chung IM (2006) A correlation between
the level of phenolic compounds and the antioxidant capacity in cooked-with-rice and vegetable soybean (Glycine max L.) varieties. Eur. Food Res Technol 224:259–270
19 Polyphenols: Classifications, Biosynthesis and Bioactivities
Garjani A, Tila D, Hamedeyazdan S, Vaez H, Rameshrad M, Pashaii M, Fathiazad F (2017) An
investigation on cardioprotective potential of Marrubium vulgare aqueous fraction against
ischaemia-reperfusion injury in isolated rat heart. Folia Morphol (Warsz) 76:361–371
Gordon NC, Wareham DW (2010) Antimicrobial activity of the green tea polyphenols
(−)-epigallocatechin- 3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia. Int J Antimicrob Agents 36:129–131
Guillermo-Gormaz J, Quintremil S, Rodrigo R (2015) Cardiovascular disease: a target for the
pharmacological effects of quercetin. Curr Top Med Chem 15(17):1735–1742
Han X, Shen T, Lou H (2007) Dietary polyphenols and their biological significance. Int J Mol Sci
8:950–988
Han X, Gao S, Cheng Y, Sun Y, Liu W, Tang L, Ren D (2012) Protective effect of naringenin-7O- glucoside against oxidative stress induced by doxorubicin in H9c2 cardiomyocytes. Biosci
Trends 6:19–25
Harikumar KB, Aggarwal BB (2008) Resveratrol: a multitargeted agent for age-associated chronic
diseases. Cell Cycle 7(8):1020–1035
Hashemzaei M, Far AD, Yari A, Heravi RE, Tabrizian K, Taghdisi SM, Sadegh SE, Tsarouhas K,
Kouretas D, Tzanakakis G (2017) Anticancer and apoptosis-inducing effects of quercetin in
vitro and in vivo. Oncol Rep 38:819–828
Heim KE, Tagliaferro AR, Bobilya DJ (2002) Flavonoid antioxidants: chemistry, metabolism and
structure-activity relationships. J Nutr Biochem 13:572–584
Hisanaga A, Mukai R, Sakao K, Terao J, Hou DX (2016) Anti-inflammatory effects and molecular
mechanisms of 8-Prenyl quercetin. Mol Nutr Food Res 60(5):1020–1032
Hong J, Smith TJ, Ho CT, August DA, Yang C (2001) Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in
human colon mucosa and colon tumor tissues. Biochem Pharmacol 62:1175–1183
Hooper L, Kroon PA, Rimm EB, Cohn JS, Harvey I, Le Cornu KA, Ryder JJ, Hall WL, Cassidy A
(2008) Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials. Am J Clin Nutr 88:38–50
Hosseinzadeh H, Nassiri-Asl M (2014) Review of the protective effects of Rutin on the metabolic
function as an important dietary flavonoid. J Endocrinol Investig 37(9):783–788
Huang C-Y, Ju D-T, Chang C-F, Reddy PM, Velmurugan BK (2017) A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer. Biomedicine
(Taipei) 7(4):23
Ichihashi M, Ueda M, Budiyanto A, Bito T, Oka M, Fukunaga M, Tsuru K, Horikawa T (2003)
UV-induced skin damage. Toxicology 189:21–39
Ide H, Lu Y, Noguchi T, Muto S, Okada H, Kawato S, Horie S (2018) Modulation of AKR1C2
by curcumin decreases testosterone production in prostate cancer. Cancer Sci 109:1230–1238
Jarial R, Thakur S, Sakinah M, Zularisam AW, Sharad A, Kanwar SS, Singh L (2018) Potent anticancer, antioxidant and antibacterial activities of isolated flavonoids from Asplenium nidus. J
King Saud Univ-Sci 30:185–192
Kano M, Kubota N, Masuoka N, Hori T, Miyazaki K, Ishikawa F (2016) Oral administration
of fermented soymilk products protects the skin of hairless mice against ultraviolet damage.
Nutrients 8:514
Katiyar SK, Mantena SK, Meeran SM (2011) Silymarin protects epidermal keratinocytes from
ultraviolet radiation-induced apoptosis and DNA damage by nucleotide excision repair mechanism. PLoS One 6:e21410
Khoo HE, Azlan A, Tang ST, Lim SM (2017) Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits. Food Nutr Res
61(1):1361779
Kim JA, Jung WS, Chun SC, Yu CY, Ma KH, Gwag JG, Chung IM (2006) A correlation between
the level of phenolic compounds and the antioxidant capacity in cooked-with-rice and vegetable soybean (Glycine max L.) varieties. Eur. Food Res Technol 224:259–270
19 Polyphenols: Classifications, Biosynthesis and Bioactivities