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Polyvinyl Alcohol (PVA/CH) at 5 and 10% w/v and employing different PVA/CH
relations of 30/70, 50/50 and 70/30 (v/v) and embed them in a 2% (v/v) Aloe vera
solution to create hydrogels. The crosslinking matrix developed from PVA/CH led
to the formation of good mechanical properties, enhance absorption capacity, and
control the release of the active compounds present in the Aloe vera gel.
18.5.13 Laxative Effects
Anthrones in aloe are a class of compounds mainly responsible for producing laxation and purgation effects (Cock 2015). Also anthraquinones have been reported to
have laxative and purgative abilities as they have been found to increases intestinal
motility, mucus secretion while also enhancing intestinal water content. Alloin A
and B have been observed to increase intestinal motility as they are reduced by
colonic flora into active compounds which irritate the GIT wall and increase motility (Sahu et al. 2013).
18.5.14 Antiseptic Activity
Presence of salicylic acid, lupeol, urea nitrogen, phenols, cinnamonic acid, and sulphur attributes to the plant’s antiseptic properties (Sahu et al. 2013).
18.5.15 Analgesic Activity
Aloe rupestris Baker’s root has been used in making decoctions that are used to get
relief from painful menstruation in infertile women. The decoctions are either
administered orally or are injected in womb (Amoo et al. 2014).
18.5.16 Antiosteoporosis Activity of the Aloe vera
Osteoporosis is a skeletal condition caused by low bone density and disorganized
bone architecture (Sun et al. 2017). This is a result of excessive rate of bone resorption activity of the osteoclast compared to the rate of bone formation of the osteoblast (Jahanian et  al. 2016). Excessive research has noted that antioxidants and
levels of ROS are significantly correlated to osteoporosis (Jia et  al. 2012; Mody
et  al. 2001; Zhao et  al. 2015). In one study, the antioxidant and antiosteoporotic
activities of 25 compounds isolated from Aloe exudates based on TRAP’s contribution on bone resorption of osteoclasts by producing ROS (Sun et al. 2017). It was
18 Aloe Species as Valuable Sources of Functional Bioactives
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