31. Gandeepan P, Müller T, Zell D, Cera G, Warratz S, Ackermann L (2019) 3d transition metals
for C–H activation. Chem Rev 119:2192–2452
32. Gensch T, Hopkinson MN, Glorius F, Wencel-Delord J (2016) Mild metal-catalyzed C–H
activation: examples and concepts. Chem Soc Rev 45:2900–2936
33. Gorunova ON, Novitskiy IM, Grishin YK, Gloriozov IP, Roznyatovsky VA, Khrustalev VN,
Kochetkov KA, Dunina VV (2018) When applying the mercury poisoning test to Palladacyclecatalyzed reactions, one should not consider the common misconception of mercury(0) selectivity. Organometallics 37:2842–2858
34. Guin S, Rout SK, Banerjee A, Nandi S, Patel BK (2012) Four tandem C–H activations: a
sequential C–C and C–O bond making via a Pd-catalyzed cross dehydrogenative coupling
(CDC) approach. Org Lett 14:5294–5297
35. Hartwig JF (2010) Organotransition metal chemistry: from bonding to catalysis. University
Science Books, Sausalito
36. Hartwig JF, Larsen MA (2016) Undirected, homogeneous C-H bond functionalization: challenges and opportunities. ACS Central Sci 2:281–292
37. Huang L, Ang TP, Wang Z, Tan J, Chen J, Wong PK (2011) On the roles of solid-bound ligand
scavengers in the removal of palladium residues and in the distinction between homogeneous
and heterogeneous catalysis. Inorg Chem 50:2094–2111
38. Hyotanishi M, Isomura Y, Yamamoto H, Kawasaki H, Obora Y (2011) Surfactant-free synthesis of palladium nanoclusters for their use in catalytic cross-coupling reactions. Chem Commun
47:5750–5752
39. Kapdi AR (2014) Organometallic aspects of transition-metal catalysed regioselective C–H bond
functionalisation of arenes and heteroarenes. Dalton Trans 43:3021–3034
40. Korwar S, Brinkley K, Siamaki AR, Gupton BF, Ellis KC (2015) Selective N-chelation-directed
C–H activation reactions catalyzed by Pd(II) nanoparticles supported on multiwalled carbon
nanotubes. Org Lett 17:1782–1785
41. Korwar S, Burkholder M, Gilliland SE, Brinkley K, Gupton BF, Ellis KC (2017) Chelationdirected C–H activation/C–C bond forming reactions catalyzed by Pd(ii) nanoparticles
supported on multiwalled carbon nanotubes. Chem Commun 53:7022–7025
42. Krasovskaya V, Krasovskiy A, Bhattacharjya A, Lipshutz BH (2011) “On water” sp3–sp2
cross-couplings between benzylic and alkenyl halides. Chem Commun 47:5717–5719
43. Krasovskiy A, Thomé I, Graff J, Krasovskaya V, Konopelski P, Duplais C, Lipshutz BH (2011)
Cross-couplings of alkyl halides with heteroaromatic halides, in water at room temperature.
Tetrahedron Lett 52:2203–2205
44. Lafrance M, Fagnou K (2006) Palladium-catalyzed benzene arylation: incorporation of catalytic
pivalic acid as a proton shuttle and a key element in catalyst design. J Am Chem Soc
128:16496–16497
45. Lafrance M, Rowley CN, Woo TK, Fagnou K (2006) Catalytic intermolecular direct arylation
of perfluorobenzenes. J Am Chem Soc 128:8754–8756
46. Leadbeater NE, Marco M (2002) Ligand-free palladium catalysis of the Suzuki reaction in water
using microwave heating. Org Lett 4:2973–2976
47. Lee AF, Ellis PJ, Fairlamb IJS, Wilson K (2010) Surface catalysed Suzuki–Miyaura crosscoupling by Pd nanoparticles: an operando XAS study. Dalton Trans 39:10473–10482
48. Liu W, Ali SZ, Ammann SE, White MC (2018) Asymmetric Allylic C–H alkylation via
palladium(II)/cis-ArSOX catalysis. J Am Chem Soc 140:10658–10662
49. Liu W, Huang X, Placzek MS, Krska SW, McQuade P, Hooker JM, Groves JT (2018) Siteselective 18F fluorination of unactivated C–H bonds mediated by a manganese porphyrin.
Chem Sci 9:1168–1172
50. Lyons TW, Sanford MS (2010) Palladium-catalyzed ligand-directed CÀH functionalization
reactions. Chem Rev 110:1147–1169
51. Martínez AV, Leal-Duaso A, García JI, Mayoral JA (2015) An extremely highly recoverable
clay-supported Pd nanoparticle catalyst for solvent-free Heck–Mizoroki reactions. RSC Adv
5:59983–59990
202
I. J. S. Fairlamb and N. W. J. Scott
for C–H activation. Chem Rev 119:2192–2452
32. Gensch T, Hopkinson MN, Glorius F, Wencel-Delord J (2016) Mild metal-catalyzed C–H
activation: examples and concepts. Chem Soc Rev 45:2900–2936
33. Gorunova ON, Novitskiy IM, Grishin YK, Gloriozov IP, Roznyatovsky VA, Khrustalev VN,
Kochetkov KA, Dunina VV (2018) When applying the mercury poisoning test to Palladacyclecatalyzed reactions, one should not consider the common misconception of mercury(0) selectivity. Organometallics 37:2842–2858
34. Guin S, Rout SK, Banerjee A, Nandi S, Patel BK (2012) Four tandem C–H activations: a
sequential C–C and C–O bond making via a Pd-catalyzed cross dehydrogenative coupling
(CDC) approach. Org Lett 14:5294–5297
35. Hartwig JF (2010) Organotransition metal chemistry: from bonding to catalysis. University
Science Books, Sausalito
36. Hartwig JF, Larsen MA (2016) Undirected, homogeneous C-H bond functionalization: challenges and opportunities. ACS Central Sci 2:281–292
37. Huang L, Ang TP, Wang Z, Tan J, Chen J, Wong PK (2011) On the roles of solid-bound ligand
scavengers in the removal of palladium residues and in the distinction between homogeneous
and heterogeneous catalysis. Inorg Chem 50:2094–2111
38. Hyotanishi M, Isomura Y, Yamamoto H, Kawasaki H, Obora Y (2011) Surfactant-free synthesis of palladium nanoclusters for their use in catalytic cross-coupling reactions. Chem Commun
47:5750–5752
39. Kapdi AR (2014) Organometallic aspects of transition-metal catalysed regioselective C–H bond
functionalisation of arenes and heteroarenes. Dalton Trans 43:3021–3034
40. Korwar S, Brinkley K, Siamaki AR, Gupton BF, Ellis KC (2015) Selective N-chelation-directed
C–H activation reactions catalyzed by Pd(II) nanoparticles supported on multiwalled carbon
nanotubes. Org Lett 17:1782–1785
41. Korwar S, Burkholder M, Gilliland SE, Brinkley K, Gupton BF, Ellis KC (2017) Chelationdirected C–H activation/C–C bond forming reactions catalyzed by Pd(ii) nanoparticles
supported on multiwalled carbon nanotubes. Chem Commun 53:7022–7025
42. Krasovskaya V, Krasovskiy A, Bhattacharjya A, Lipshutz BH (2011) “On water” sp3–sp2
cross-couplings between benzylic and alkenyl halides. Chem Commun 47:5717–5719
43. Krasovskiy A, Thomé I, Graff J, Krasovskaya V, Konopelski P, Duplais C, Lipshutz BH (2011)
Cross-couplings of alkyl halides with heteroaromatic halides, in water at room temperature.
Tetrahedron Lett 52:2203–2205
44. Lafrance M, Fagnou K (2006) Palladium-catalyzed benzene arylation: incorporation of catalytic
pivalic acid as a proton shuttle and a key element in catalyst design. J Am Chem Soc
128:16496–16497
45. Lafrance M, Rowley CN, Woo TK, Fagnou K (2006) Catalytic intermolecular direct arylation
of perfluorobenzenes. J Am Chem Soc 128:8754–8756
46. Leadbeater NE, Marco M (2002) Ligand-free palladium catalysis of the Suzuki reaction in water
using microwave heating. Org Lett 4:2973–2976
47. Lee AF, Ellis PJ, Fairlamb IJS, Wilson K (2010) Surface catalysed Suzuki–Miyaura crosscoupling by Pd nanoparticles: an operando XAS study. Dalton Trans 39:10473–10482
48. Liu W, Ali SZ, Ammann SE, White MC (2018) Asymmetric Allylic C–H alkylation via
palladium(II)/cis-ArSOX catalysis. J Am Chem Soc 140:10658–10662
49. Liu W, Huang X, Placzek MS, Krska SW, McQuade P, Hooker JM, Groves JT (2018) Siteselective 18F fluorination of unactivated C–H bonds mediated by a manganese porphyrin.
Chem Sci 9:1168–1172
50. Lyons TW, Sanford MS (2010) Palladium-catalyzed ligand-directed CÀH functionalization
reactions. Chem Rev 110:1147–1169
51. Martínez AV, Leal-Duaso A, García JI, Mayoral JA (2015) An extremely highly recoverable
clay-supported Pd nanoparticle catalyst for solvent-free Heck–Mizoroki reactions. RSC Adv
5:59983–59990
202
I. J. S. Fairlamb and N. W. J. Scott